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Aging Medicine
Scopus
ISSN 2475-0360 · Wiley · 379 artikel di indeks
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Artikel Jurnal
Impact of Acute Functional Decline on Frailty and Mortality in Acutely Hospitalized Older Persons
ABSTRACT Objectives Older persons are often referred to emergency departments due to acute functional decline, that is, reduced activities of daily living occurring in the days before hospitalization, frequently driven by acute medical conditions. We aimed to describe frailty in the oldest…
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Artikel Jurnal
Association Between Hair Cortisol, Sarcopenia, and Sarcopenic Obesity: Results From the ELSA‐Brasil Study
ABSTRACT Objectives Hair cortisol has been increasingly used as an important biomarker of chronic stress, as it reflects prolonged systemic exposure to cortisol over time. Such exposure has been associated with alterations in body composition; however, the associations with sarcopenia and…
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Artikel Jurnal
Advancing Geriatric Hospice Care in China: An Interpretation and Critical Analysis of the New National Standard WS/T 844–2024
ABSTRACT China's demographic landscape is undergoing a dramatic transformation. With over 297 million people aged 60 and above—comprising 21.1% of the total population—the nation faces unprecedented challenges in providing adequate end‐of‐life care for its elderly citizens. It is against this…
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Evaluation and Ranking for Scientific, Transparent and Applicable of Chinese Geriatrics Guidelines and Consensus Published in 2023
ABSTRACT Objectives This study aims to evaluate the Scientific, Transparent, and Applicable Rankings (STAR) of guidelines and consensus published in Chinese geriatric medicine journals in 2023. Methods The working group conducted a systematic search in eight major Chinese and English databases for…
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Shared Metabolic–Proteinopathy Axis in Alzheimer's Disease and Parkinson's Disease: Evidence for a Convergent but Not Identical Disease Spectrum
ABSTRACT Alzheimer's disease (AD) and Parkinson's disease (PD) are the two most prevalent neurodegenerative disorders globally and have long been classified as clinically and pathologically distinct syndromes. AD is defined by amyloid‐β (Aβ) plaques and tau‐positive neurofibrillary tangles, whereas…
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Artikel Jurnal
Long Noncoding RNAs in Aortic Dissection: Mechanistic Roles and Therapeutic Potential
ABSTRACT Aortic dissection (AD) is a life‐threatening vascular disorder characterized by separation of the layers of the aortic wall, primarily triggered by an intimal tear or an intramural hemorrhage. Age is a well‐recognized and critical risk factor for AD. Epidemiological evidence consistently…
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Expert Consensus on the Management of Obesity in Older Adults (2026 Edition)
ABSTRACT Obesity in older adults has become a prominent public health issue. Owing to age‐related physiological changes and multimorbidity, obesity in this population is associated with complex clinical manifestations and markedly increased difficulty in management. Based on this, a…
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Insights Into the Mechanisms of Biological Aging That Guide Translational and Clinical Research
ABSTRACT Understanding the molecular mechanisms of aging guides the development of prevention, intervention, and treatment strategies to reduce the incidence of common age‐associated diseases. Over the past decades, the proposed key features (hallmarks) of aging cells have directly or indirectly…
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Beneficial Body Mass Index for Age‐Related Kidney Function in Males and Females
ABSTRACT Objectives Kidney function declines with aging, leading to a high prevalence of age‐related disease. Concurrently, the increasing prevalence of overweight and obesity may influence age‐related kidney changes. This study aims to clarify the relationship between body mass index (BMI) and…
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Artikel Jurnal
Expert Consensus on Influenza Vaccine and Pneumococcal Vaccination in Elderly People With Chronic Respiratory Diseases (2024)
ABSTRACT Chronic respiratory diseases pose a serious threat to the health of the population due to their high incidence, high disability rate, and poor prognosis. It is necessary to improve the prevention and treatment status of chronic respiratory diseases. Vaccination against influenza and…
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Artikel Jurnal
Biomarkers of Sarcopenia: Current Status and Future Perspectives
ABSTRACT Sarcopenia is an age‐related skeletal muscle disorder characterized by progressive declines in muscle mass, strength, and physical function, which profoundly impair quality of life in older adults. Although current clinical guidelines propose various diagnostic approaches and cutoff…
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Artikel Jurnal
Lymph Node Metastasis Pattern and Influencing Factors in Esophageal Squamous Cell Carcinoma
ABSTRACT Objectives To investigate the lymph node metastasis (LNM) pattern of esophageal squamous cell carcinoma (ESCC) and identify factors associated with LNM: Methods A retrospective study was conducted including 388 patients with ESCC who underwent curative resection at the First Affiliated…
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Artikel Jurnal
Effect of Lactulose on the Intestinal Flora of Elderly Constipation Patients With Chronic Renal Insufficiency
ABSTRACT Objectives To evaluate the efficacy of lactulose in the treatment of elderly constipation patients with chronic renal insufficiency and its influence on renal function. Methods They were divided into the lactulose group (n = 30) and polyethyleneglycol (PEG) group (n = 26). The lactulose…
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The Effect of Resistance Training and Ursolic Acid on the PI3K‐AKT‐mTOR Pathway in Aged Diabetic Rats: A Comparative Study
ABSTRACT Objectives Sarcopenia, characterized by age‐related muscle loss, worsens in diabetes due to anabolic resistance. Ursolic acid (UA), a natural compound with anabolic and anti‐catabolic effects, may mitigate sarcopenia by enhancing anabolic pathways. This study examined the effects of 8…
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Artikel Jurnal
Morbidity Among the Aging Population in Northern Bangladesh: An Epidemiological Study
ABSTRACT Objective Morbidity is a prevalent public health issue especially among the aging population worldwide. As the risks of morbidity increase with age, aging populations increasingly become a socioeconomic burden on their families. However, studies on morbidity among aging populations in…
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Validation of the Patient Health Questionnaire‐2 (PHQ‐2) in Detecting Depression Among Older Adults
ABSTRACT Objectives Depression screening tools like the Patient Health Questionnaire‐2 (PHQ‐2) are commonly used to detect depression. However, its performance in elderly populations has been less extensively studied compared to its broader adult use. This study evaluates the PHQ‐2's ability to…
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The Impact of Early Postoperative Blood Pressure Variability and Hypertension Status on 90‐Day Functional Outcomes in Acute Ischemic Stroke due to Large Vessel Occlusion Patients Treated With Mechanical Thrombectomy
ABSTRACT Objectives To investigate the impact of early postoperative blood pressure variability (BPV) on 90‐day functional outcomes in patients with acute ischemic stroke due to large vessel occlusion (AIS‐LVO) undergoing mechanical thrombectomy, and to assess its interaction with pre‐existing…
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Artikel Jurnal
The Spectrum of Biopsy‐Proven Renal Diseases in Chinese Elderly Patients and Its Temporal Shift Over 20 Years: A Retrospective Cohort Study
ABSTRACT Objective To investigate the longitudinal pathological changes in the spectrum of biopsy‐proven renal diseases among elderly patients over the past 20 years at a single center in China. Methods We retrospectively enrolled patients aged ≥ 60 years who underwent renal biopsy at Beijing…
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Factors Affecting Recollapse of the Augmented Vertebrae After Percutaneous Vertebral Augmentation: A Prospective Study
ABSTRACT Objective To investigate the relevant factors of augmented vertebrae recollapse after percutaneous vertebral augmentation (PVA) for the treatment of osteoporotic vertebral compression fractures (OVCFs). Method A prospective study was performed on 116 patients who were diagnosed with…
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Artikel Jurnal
Defining Frailty in Chinese‐Language Biomedical Literature (2014–2024): A Decade of Conceptual Evolution
ABSTRACT Frailty is increasingly recognized as a central concept in aging research and clinical practice, which reflects reduced physiological reserve and heightened vulnerability to stressors. While extensively examined in Western biomedical literature, how frailty is defined and conceptualized in…