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International Journal of Reproductive BioMedicine
Scopus
ISSN 2476-4108 · Shahid Sadoughi University of Medical Sciences · 974 artikel di indeks
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Artikel Jurnal Teks lengkap
The effect of intrauterine injection of autologous peripheral blood mononuclear cells on clinical pregnancy in women with recurrent implantation failure
This is a Letter to the Editor and does not have an abstract. Please download the PDF or view the article in HTML.
Juga tersedia di: DOAJ
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Artikel Jurnal Teks lengkap
Effects of supplementation with two probiotic strains on metabolic profile, hormonal status, oxidative stress, and quality of life in women with polycystic ovary syndrome: A study protocol for a randomized clinical trial
Background: Polycystic ovarian syndrome (PCOS) is a common endocrine disorder in women, associated with insulin resistance, ovulatory dysfunction, hyperandrogenism, and inflammation. Current treatments often focus on symptoms rather than underlying causes, emphasizing the need for comprehensive…
Juga tersedia di: DOAJ
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Artikel Jurnal
Unveiling the molecular nexus: Long non-coding RNAs, RNA-binding proteins, and DNA damage in ovarian ischemia-reperfusion injury: A narrative review
Ovarian ischemia-reperfusion injury (IRI) is a pathology that entails the interruption of blood supply to the ovary and subsequent restoration of flow, causing tissue damage and dysfunction. Therefore, the identification of cisternal components, long non-coding RNAs (lncRNAs), and RNA-binding…
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Protective effects of selenium nanoparticles against X-ray-induced testicular damage in rats: An integrated experimental and Monte Carlo simulation study
Background: Ionizing radiation induces oxidative damage in biological tissues, particularly in sensitive organs such as the testes. Selenium nanoparticles (SeNPs), known for their antioxidant properties, may help mitigate this damage. Objective: This study investigated the protective effects of…
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Artikel Jurnal
Integrative RNA-seq analysis reveals immune-related hub genes NR4A1 and FOSB in recurrent spontaneous abortion: A bioinformatics study
Background: Recurrent spontaneous abortion (RSA) impacts 1–5% of women of reproductive age, constituting a significant health issue. Despite advances in our understanding of RSA, the fundamental molecular mechanisms remain inadequately defined. Examining differentially expressed genes (DEGs) in RSA…
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A special perspective on human fertilization: The role of sperm capacitation proteins and channels: A narrative review
Sperm undergo a last step of maturation known as capacitation in the female reproductive system, which prepares themselves to fertilize the ovum. Mechanisms of capacitation include changes in membrane composition, electrolyte concentration, pH levels, cellular and molecular pathways, signaling…
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Fimbria torsion as a rare cause of lower abdominal pain: A case report and literature review
Background: Isolated fimbrial torsion is a rare gynecological emergency that can lead to severe complications if not promptly diagnosed. Its clinical presentation often mimics more common causes of abdominal pain, creating a significant diagnostic challenge. Case Presentation: This case report…
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An experimental study on shrimp bioactive peptides restoring testicular function in a rat model of fatty liver disease via autophagy, redox balance, and energy transporters
Background: Non-alcoholic fatty liver disease is a widely prevalent condition in the modern era, with potential adverse effects on fertility and the reproductive system. Objective: This experimental study investigated the adverse effects of non-alcoholic fatty liver disease induced by a high-fat…
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Complex in vitro fertilization laboratory factors affecting sperm DNA integrity: A narrative review
Sperm DNA fragmentation (SDF) is increasingly recognized as a key biomarker of male fertility, influencing natural conception and assisted reproduction clinical outcomes. Unlike conventional semen parameters, SDF directly reflects chromatin integrity and the sperm’s genetic potential…
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Comparison of frozen embryo transfer outcomes in hormonal vs. mild stimulation protocols in polycystic ovary syndrome women: A randomized controlled trial
Background: Polycystic ovary syndrome (PCOS) is a leading cause of anovulatory infertility. In women undergoing frozen embryo transfer, the method of endometrial preparation (hormone replacement therapy [HRT] or mild ovarian stimulation [MOS]) can affect pregnancy outcomes. Letrozole-based MOS…
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Association of polymorphic loci of the matrix metalloproteinase genes with the development of fetal growth retardation: A case-control study
Background: Matrix metalloproteinases (MMPs) play a crucial role in successful pregnancy as molecular regulatory factors of the developing organism. Additional studies focusing on MMPs activity and function in fetal growth retardation (FGR) may help in the search for diagnostic markers of this…
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Determining factors associated with the number of oocytes with appropriate morphology in infertile women: A cross-sectional study
Background: Infertility affects millions of couples worldwide. The number of morphologically normal oocytes (MNO) is a key determinant of assisted reproductive technology success. Accurate identification of influencing factors is limited by excess zeros in real-world clinical data. Objective: This…
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Artikel Jurnal
Expression of TGFB1 and ERK in cumulus cells: Implications for oocyte maturation in women with polycystic ovary syndrome: A cross-sectional study
Background: Polycystic ovary syndrome (PCOS) is an endocrine disorder that negatively influences oocyte developmental competence. In vitro maturation (IVM) is an approach to reduce complications in the treatment of PCOS-related infertility. The genes regulating oocyte maturation should be…
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Comparison of intracytoplasmic sperm injection and in vitro fertilization outcomes in double stimulation with conventional protocol in participants with poor ovarian response with minimal injection: An RCT
Background: In women with poor ovarian response (POR), the quantity and quality of oocytes produced by the ovaries decrease, resulting in poor-quality embryos. Ovarian stimulation, by increasing the number of oocytes and embryos, improves in vitro fertilization (IVF) outcomes. Objective: The aim of…
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A novel homozygous growth differentiation factor 9 variant associated with premature ovarian insufficiency: A case report
Background: Premature ovarian insufficiency (POI) is a condition marked by reduced ovarian function. The variants in several genes have been identified in association with POI. Growth differentiation factor 9 (GDF9) is one of these genes, which encodes a secreted protein with an essential role in…
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When 105% is too much: Reflections on boundaries and statistical methods in diagnostic test accuracy meta-analytical modeling: A letter to the editor
This is a Letter to the Editor and does not have an abstract. Please download the PDF or view the article in HTML.
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Artikel Jurnal
Artificial intelligence in infertility treatment: Applications, challenges, and future directions: A narrative review
The application of artificial intelligence (AI) is expanding in all fields of medicine, including infertility treatment. This article examines the different uses of AI in reproductive healthcare. This article focuses on predictive models, imaging processing, and personalized therapeutic strategies…
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Artikel Jurnal
Clinician-related variability as an independent determinant of in vitro fertilization success: A retrospective cohort study of intracytoplasmic sperm injection cycles
Background: In vitro fertilization (IVF) outcomes are shaped by individual factors, laboratory conditions, and clinician performance; however, while embryologists and laboratory conditions are well studied, clinician-related variables remain less explored. Objective: This study aims to evaluate…