552 hasil
Menampilkan 1–20 · 0,13 detik · RSS
Advances in Rheumatology
Scopus
ISSN 2523-3106 · BMC · 552 artikel di indeks
-
Artikel Jurnal
Review of fibromyalgia treatment guidelines: part 2 – pharmacological treatment
Abstract Fibromyalgia is a complex condition characterized by widespread chronic pain, fatigue, and sleep disturbances, which significantly affect quality of life. Its pathophysiology involves central sensitization (CS) and changes in neurotransmitters. Management is challenging and requires a…
-
Artikel Jurnal
Multidimensional contributors to disease burden in axial spondyloarthritis: role of central sensitization, catastrophizing and sleep disturbance
Abstract Introduction Axial spondyloarthritis (axSpA) imposes a multidimensional burden that is not fully explained by inflammation. Central sensitization (CS), pain catastrophizing (PC), and sleep disturbance may amplify symptoms and worsen outcomes. This study aimed to assess the prevalence and…
-
Artikel Jurnal
Blood levels of brain-derived neurotrophic factor (BDNF) in psoriasis: a systematic review and meta-analysis
Abstract Introduction Psoriasis is a chronic inflammatory skin condition affecting 0.1–1.5% of the global population. The condition is linked to impaired quality of life and increased morbidity. Brain-derived neurotrophic factor (BDNF) is a neurotrophin associated with neuronal development and…
-
Artikel Jurnal
Brazilian Society of Rheumatology’s fibromyalgia treatment guidelines – part I: monitoring and non-pharmacological management
Abstract Fibromyalgia is one of the most prevalent rheumatologic conditions, affecting millions of individuals worldwide. It is characterized by widespread chronic pain accompanied by symptoms such as fatigue, sleep disturbances, and cognitive impairments. In Brazil, fibromyalgia is the second most…
-
Artikel Jurnal
Registry of idiopathic inflammatory myopathies (REMAS) from nine Brazilian research centers linked to tertiary care and teaching hospitals
Abstract Objectives Idiopathic inflammatory myopathies (IIMs) are a group of rare chronic inflammatory diseases that affect the muscle, skin, and other organs. There is a severe lack of evidence for current treatment protocols for IIMs. The rarity of these conditions requires multicenter…
-
Artikel Jurnal
Impact of male sex in clinical and laboratory features of systemic sclerosis
Abstract Background Although systemic sclerosis (SSc) predominantly affects the female sex, male patients tend to present a more severe visceral profile and worse prognosis. This study aims to analyze the clinical and laboratory characteristics of male patients in a large single SSc cohort. Methods…
-
Artikel Jurnal
Brazilian Society of Rheumatology – 2025 recommendations on vaccination in immune-mediated rheumatic diseases
Abstract Background Patients with immune-mediated rheumatic diseases (IMRD) are at increased risk for infections due to both disease-related immune dysregulation and immunosuppressive therapy. Despite the benefits of vaccination, immunization rates in this population remain suboptimal, often due to…
-
Artikel Jurnal
Diagnostic accuracy of synovial fluid progranulin vs. C-reactive protein in septic arthritis: a comparative biomarker study
Abstract Background Septic arthritis (SA) is a rapidly progressive joint disease that can lead to cartilage damage if not treated promptly. A prompt and accurate distinction between SA and inflammatory arthritis (IA) is essential for establishing an optimal treatment plan. Progranulin (PRGN), an…
-
Artikel Jurnal
Nutritional screening and extraglandular manifestations in Sjögren disease: a cross-sectional study using the controlling nutritional status score and prognostic nutritional index
Abstract Background Sjögren disease (SjD) is an autoimmune disorder marked by exocrine gland dysfunction and systemic extraglandular manifestations (EGM). While nutritional status plays a key role in chronic diseases, its association with EGM in SjD remains underexplored. Aims This study aims to…
-
Artikel Jurnal
Glial fibrillary acidic protein in fibromyalgia: its serum levels and antibodies
Abstract Background Fibromyalgia is a stress-related disorder in which dorsal root ganglia (DRG) may play an important pathogenic role. DRG exhibit unique stress-induced, pro-algesic physio-anatomy, where each pain-sensing nerve fiber soma is encased and interacts with immune-competent satellite…
-
Artikel Jurnal
Diagnostic accuracy of the leukocyte esterase test for native joint septic arthritis and prosthetic joint infections: a systematic review and meta-analysis
Abstract Backgrounds Diagnosing infectious arthritis, including native joint septic arthritis (NJSA) and prosthetic joint infections (PJI), is challenging but critical due to significant morbidity and mortality risks. The leukocyte esterase (LE) test shows promise as a quick, inexpensive diagnostic…
-
Artikel Jurnal
The distinct musculoskeletal phenotypes of Type 1 and Type 2 diabetes: a sonographic characterization of enthesopathy burden
Abstract Objective Musculoskeletal complications represent a significant burden in diabetes, yet the distinct presentation between Type 1 (T1DM) and Type 2 Diabetes Mellitus (T2DM) remains under-characterized. This study aimed to evaluate and quantify the burden of rheumatic manifestations and…
-
Artikel Jurnal
Irisin and myostatin serum levels in patients with established rheumatoid arthritis: correlation with radiographic progression and lean body mass
Abstract Background The myokines irisin and myostatin participate in bone and skeletal muscle homeostasis and may characterize the clinical status of these tissues. The study aimed to evaluate the association of myokines serum levels with one-year radiographic progression and lean mass in…
-
Artikel Jurnal
Validation of a semi-quantitative ultrasonography score for knee synovitis in juvenile idiopathic arthritis and its association with clinical findings
Abstract Background Ultrasonography is an important tool for assessing synovitis in juvenile idiopathic arthritis (JIA), but the reproducibility of semi-quantitative scores and their relationship with clinical findings still need clarification. We aimed to evaluate the intra- and inter-observer…
-
Artikel Jurnal
Psychosocial and behavioral correlates of persistent pain post disease-modifying treatment change in rheumatoid arthritis: a 12-month cohort study
Abstract Background Pain is a debilitating and persistent symptom of rheumatoid arthritis (RA), associated with impaired functional capacity and reduced quality of life. Despite targeted disease-modifying treatments, many RA patients experience persistent pain, suggesting mechanisms operating…
-
Artikel Jurnal
Post-publication corrections of rheumatology articles: a comprehensive analysis
Abstract Objectives With the growing volume of scientific publications in recent years, both unintentional errors and instances of scientific misconduct have become increasingly common. These errors may include typographical mistakes, inaccuracies in author information, and issues in figures…
-
Artikel Jurnal
Do ethnoracial differences exist among antiphospholipid antibody-positive patients with no other systemic autoimmune diseases: results from the APS ACTION registry
Abstract Objective The APS ACTION Registry was created to study long-term outcomes in persistently antiphospholipid antibody (aPL)-positive patients. The objectives of this study were to examine the ethnoracial differences in clinical and laboratory characteristics of aPL-positive patients with no…
-
Artikel Jurnal
Evaluation of the prevalence of overactive bladder syndrome in patients with rheumatoid arthritis
Abstract Introduction The aim of this study was to evaluate the frequency of overactive bladder syndrome (OAB) in patients with rheumatoid arthritis (RA) and its relationship with clinical parameters and central sensitization (CS). Methods This cross-sectional study included 95 patients diagnosed…
-
Artikel Jurnal
Home-based transcranial direct current stimulation for persistent pain state in rheumatoid arthritis: a randomized trial
Abstract Background Although effectively controlling inflammation, up to 50% of patients with rheumatoid arthritis (RA) experience persistent pain, associated with central sensitization and neuroinflammation. Home-based transcranial direct current stimulation (tDCS) has shown efficacy in chronic…