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Sokoto Journal of Medical Laboratory Science
ISSN 2536-7153 · Hammer Head Production Limited · 531 artikel di indeks
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Artikel Jurnal
Neisseria gonorrhoea and associated risk factors among the residents of Kwali Area Council, FCT, Abuja, Nigeria.
Sexually transmitted infections pose significant Public Health concern in Nigeria, impacting individuals and communities across the nation and Neisseria gonorrhoea, commonly known as gonorrhoea remains a prevalent yet often silent sexually transmitted infection that has threatened the populace all…
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Artikel Jurnal
Vertical Transmission of Hepatitis E Virus Infection Among Antenatal Attendees in Ekiti, Nigeria: A Longitudinal Cohort Study
Hepatitis E virus (HEV) infection in pregnancy is a serious health issue associated with spontaneous miscarriage, preterm labour and also accounts for 30% maternal mortality in the third trimester. This study was carried out to determine the anti-HEV prevalence, HEV vertical transmission and…
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Artikel Jurnal
Effects of Aqueous Extract of Syzygium aromaticum (Clove) On Mercury Chloride-Induced Toxicity in The Hippocampus of Adult Wistar Rats
Mercury is a neurotoxic substance that crosses the blood-brain barrier and disrupts neuronal functions by inducing oxidative stress (OS), impairment of neurotransmission, and neuronal damage, resulting in cognitive and motor dysfunction. Since OS is one of the mechanisms of actions of mercury…
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Artikel Jurnal
Histological and Biochemical Changes in The Uteri; Centella Asiatica as an Antifertility Agent
This research investigated the adverse effect of Centella asiatica on the female reproductive system, particularly the uterus. The use of alternative medicine has gained more attention in recent years. Plants such as Centella are reported to possess several medicinal benefits, especially in nervous…
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Artikel Jurnal
Dose-Dependent Progression and Physiological Impact of Salmonella Typhi Infection in Albino Rats
The progression of typhoid fever was investigated in Albino rats experimentally infected with Salmonella typhi at Ebonyi State University, Abakaliki. A total of 20 albino rats were divided into five groups, each containing four rats. Group A served as the negative control, while Groups B, C, D, and…
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Artikel Jurnal
The Relationship Between Body Mass Index (BMI) and Reproductive Hormone Levels and Sperm Parameters in Relatively Healthy Individuals
Infertility affects approximately 13% to 15% of couples worldwide, with 1 in 5 couples unable to achieve pregnancy within the first year of trying. Obesity is recognized as a significant modifier of reproductive hormones, with evidence suggesting its role in declining sperm parameters, given the…
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Artikel Jurnal
Jatropha Tanjorensis Leaf Extract Modulation on Glycoprotein IX, 1B Alpha and 1B Beta in Albino WistarRats
Jatropha tanjorensis leave extract is a common vegetable in Southern Nigeria use in the stoppage of bleeding in open injuries. Glycoprotein IX, 1Bá and 1Bâ complex plays a significant role in platelet physiology and pathology. It is observed to interact with von Willibrand factor (vWF) on the…
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Artikel Jurnal
Histopathologic Pattern of Oropharyngeal Tumours Among Patients Seen in National Ear Care Centre, Kaduna: A 10 Year Retrospective Study From 2014-2023
Oropharyngeal tumours including squamous cell carcinoma, tonsil cancer, benign and inflammatory lesions are a group of diseases with abnormal cells that have potential to grow locally and spread to other parts of the body mainly found in the oral cavity. Oral and pharyngeal cancer, grouped…
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Artikel Jurnal
Prediction of antibiotic target proteins of streptococcus pyogenes using network pharmacology approach
Many extracellular components secreted by Group A Streptococcus, also called S. pyogenes, are believed to be virulence factors. Therefore, this study aimed to predict antibiotic target proteins from S. pyogenes, rank the proteins based on their text-mining scores using the network pharmacology…
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Artikel Jurnal
Pathophysiology and Current Laboratory Investigations of Glucose-6-Phosphate Dehydrogenase Deficiency.
Glucose-6-phosphate dehydrogenase catalyses the rate-determining step in the pentose phosphate pathway. Its activity is a key determinant of the reduced nicotinamide adenine dinucleotide phosphate to oxidized nicotinamide adenine dinucleotide phosphate (NADPH-to-NADP+) ratio in the cytoplasm and…
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Artikel Jurnal
Preparation of Plasma-based Medicinal Products in Combating Coagulation Factors Deficiencies by Apheresis Technique
The production of plasma-based medicinal products is vital in the treatment and management of coagulation factor deficiencies, immune diseases, and various severe medical conditions. This study focuses on the preparation of plasma-based products using the apheresis technique, with a particular…
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Artikel Jurnal
Study of Coagulation Markers in Pregnant Women at University of Port Harcourt Teaching Hospital
Pregnancy is a complex physiological condition that causes significant changes in the haematological profile of women, including changes in platelet indices and fibrinogen levels. The aim of this study was to investigate coagulation markers in pregnant women at University of Port Harcourt Teaching…
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Artikel Jurnal
Assessment of Full Blood Count and Some Iron Parameters Among Pregnant Women In Specialist Hospital, Sokoto, Nigeria.
Iron deficiency anaemia (IDA) is the single most prevalent nutritional deficiency worldwide. It is a major public health problem particularly among pregnant women in developing countries with adverse effects on the mother and the newborn. The aim of the study was to investigate the effect of…
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Artikel Jurnal
Haematological and Coagulation Parameters in Newly Diagnosed Systemic Hypertensive Patients: A Comparative Study of elevated vs. normal CRP level
Systemic hypertension is progressively acknowledged as not just a cardiovascular condition but also one associated with systemic inflammation. In recent years, growing evidence has suggested an intricate relationship between inflammation and haematological and coagulatory parameters in systemic…
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Artikel Jurnal
Evaluation of Some Hemostatic Parameter in Albino Wistar Rats Administered Tramadol
Tramadol, a synthetic analogue of codeine, is an opioid with central effects, recommended for its lower abuse potential and reduced respiratory depression compared to other opioids. It is used to manage acute and chronic pain of moderate to severe intensity. However, tramadol abuse has increased…
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Artikel Jurnal
Occurrence of Cytomegalovirus and Human Immunodeficiency Virus Among Antenatal Women in University of Port Harcourt Teaching Hospital
The potential effects of cytomegalovirus (CMV) and human immunodeficiency virus (HIV) on maternal and neonatal health make them serious public health concerns, especially for pregnant women. This study aims to determine the occurrence of CMV and HIV among antenatal women and to assess the…
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Artikel Jurnal
A Search for FDA Approved Drugs with Anti-ulcerative Effects: A computational Based Drug Repositioning Study
Peptic ulcer disease (PUD) remains a significant global health concern, with millions affected annually. Current treatments, such as proton pump inhibitors and H2 receptor antagonists, face limitations like drug resistance and side effects. Drug repurposing, utilizing FDA-approved drugs, offers a…
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Artikel Jurnal
Impact of Obesity on Hormonal Balance in Women Resident in Port-Harcourt, Rivers State, Nigeria.
Obesity, a global public health concern, disrupts hormonal balance in women, adversely affecting reproductive and metabolic health. This study aimed to evaluate the impact of obesity on key hormones such as leptin, insulin, estradiol, and testosterone, and its association with menstrual…
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Artikel Jurnal
Unveiling Alcohol's Modern Health Burden: A Comprehensive Exploration of Biological Repercussions
Alcohol's historic role in human culture contrasts with its modern health burden. This review synthesizes extensive research on the adverse effect of alcohol on organ systems, contributing to chronic diseases. Global data shows that alcohol consumption has a substantial impact on disease burden and…
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Artikel Jurnal
Effects of Aqueous Leaf Extract of Mimosa pudica on Insect Repellent–Induced Injury in the Trachea of Adult Wistar Rats
The use of insect repellent in occupational settings can lead to insecticide poisoning, a serious health hazard that can have severe consequences, including morbidity and mortality, if left untreated. The aim of this study was to investigate the effects of aqueous leaf extract of Mimosa pudica on…