139 hasil
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Postępy Mikrobiologii
ISSN 2545-3149 · Sciendo · 139 artikel di indeks
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Artikel Jurnal
Pathogenic Bacteria Variation in Hydroelectric Reservoirs: Case of Kossou, Taabo and Faé in Côte D'ivoire
Recent studies have shown that the Taabo, Kossou, and Faé reservoirs are contaminated by faecal pollutants, which could pose health risks to users due to a potentially high abundance of pathogenic bacteria. Accordingly, a monitoring study was planned to assess variation in pathogen abundance…
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Artikel Jurnal
Detection of Virulence Genes and ABC Genotypes in Candida Albicans Isolates from Candidemia Patients
Candidemia is the most common form of invasive fungal infection, and is associated with high mortality rates particularly in intensive care patients. In this study, 50 C. albicans strains isolated from blood samples were genotyped by 25S intron analysis, and the presence of virulence genes was…
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Trypsin-Activated Parasporal Proteins from Native Bacillus thuringiensis Isolates Reduce Staphylococcus aureus Virulence and Biofilm Formation In vitro
Antibiotics are pivotal for treating Staphylococcus aureus infections, but overuse has led to multidrug-resistant (MDR) strains, necessitating alternative strategies. Targeting virulence factors, rather than bacterial survival, offers a promising approach to combat resistance. This study evaluated…
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Artikel Jurnal
Antimicrobial Resistance in Klebsiella pneumoniae: Mechanisms, Epidemiology, and Emerging Threats
Currently, one of the most serious threats to public health is the rapid spread of multidrug–resistant (MDR) and highly virulent Klebsiella pneumoniae (hvKp). In these strains, various antibiotic resistance genes (ARGs) are frequently detected, including several novel ones first identified in this…
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Artikel Jurnal
Pilot Study of the Microbiological Diversity of the Urinary Tract of Healthy Young Men in Poland
The urinary tract microbiota (urobiota) in healthy individuals remains understudied, particularly in men. Methods: Expanded quantitative urine cultures were performed on 40 asymptomatic, presumably healthy males (18–40 years). Results: 88% of samples showed bacterial growth, predominated by…
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Artikel Jurnal
The Role of Sialidases in the Development of Bacterial Vaginosis and their Use as Potential Markers in the Diagnosis of Vaginal Infections
Bacterial vaginosis (BV) is an inflammatory condition of the vagina with a polyetiological origin, most commonly associated with an overgrowth of anaerobic bacteria such as Gardnerella vaginalis or Prevotella spp. Pathogens compromise the protective barrier of the vagina through multiple…
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Artikel Jurnal
MALDI-TOF MS-Based Detection of Antimicrobial Resistance: Biomarkers, Assays and Clinical Applications – A Critical Review
The MALDI-TOF MS technique is now playing a major role in improving microbial diagnostics by enabling rapid and accurate identification of pathogens from minimal amounts of biological material. In recent years, its application has been extended to the detection of antimicrobial resistance trough…
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Artikel Jurnal
Microbial Hazards in Post-Flood Soils – An Overview
Becoming increasingly common across Poland and Europe. However, to date, microbiological studies have primarily focused on water intakes and the presence of indicator bacteria (i.e., fecal bacteria) in flood sediments. Data on soil microbial loads are lacking. This short review synthesizes the…
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Artikel Jurnal
Parasporal δ-Endotoxins of Bacillus Thuringiensis: Potentials and Challenges as a New Frontier in the Fight Against Cancer
Parasporins (PSs), also known as delta endotoxins or Mammalian Pore-forming Proteins (Mpp), are non-hemolytic, non-insecticidal proteins secreted by Bacillus thuringiensis. They exhibit selective anticancer activities against various human tumor cell lines by recognizing and binding to specific…
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Artikel Jurnal
Octenidine Dihydrochloride – Antimicrobial Activity, Adaptation and Clinical Application
Octenidine dihydrochloride (OCT) is an antiseptic used for the prevention of wound infections, treatment of wounds and for treating oral infections. The spectrum of OCT’s activity includes Gram-positive and Gram-negative bacteria, as well as fungi, including multidrug-resistant (MDR) strains. For…
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Artikel Jurnal
Antiseptics: Their Characteristics, Application and Challenges in the 21St Century Resulting from the Spread of Antimicrobial Resistance (AMR)
In the context of escalating microbial resistance to antibiotics, antiseptics are gaining prominence as a critical component of infection prevention. Concurrently, the widespread and increasing use of these biocides, particularly within healthcare settings, has prompted concerns regarding their…
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Artikel Jurnal
Akkermansia Muciniphila is Associated with Human Health: What Should we Know?
Akkermansia muciniphila is a gut bacterium that has recently attracted considerable attention in microbiota research. Its presence in the gut is associated with improved metabolic health, enhanced gut barrier integrity, and modulation of the immune system. However, potential risks related to its…
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Linking Gut Microbiota and Irritable Bowel Syndrome (Ibs): A Review
Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder with an increasing global prevalence. The International Classification of Diseases (ICD) system typically categorizes IBS into four subtypes based on symptomatology. The objective of this review is to provide a concise synthesis…
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Artikel Jurnal
Understanding Probiotics, Prebiotics, Synbiotics, and Postbiotics: A Comprehensive Review of the Newest Definitions, Selected Strains and Products
In recent years the field of probiotics, prebiotics, synbiotics and postbiotics has been extensively studied. Preparations including live and inanimate microorganisms, their parts and substances that selectively stimulate their growth, are promising in treatment or amelioration of symptoms in many…
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Porphyromonas Gingivalis Virulence Factors and their Role in Undermining Antimicrobial Defenses and Host Cell Death Programs in the Pathobiology of Chronic Periodontal Disease
Periodontitis (PD) is a chronic inflammatory disease that affects a significant portion of the global population. In susceptible individuals, the disease is driven by dysbiotic microbiota on the tooth surface below the gum line, progressively eroding the tooth--supporting structures of the…
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Artikel Jurnal
Description of Methodology for Testing the Synergistic and Additive Effects of Antibiotics in Vitro
Given the dynamic growth of antibiotic resistance observed over the past few decades, new therapeutic methods for life-threatening infections are crucial. Effective treatment of infections caused by multidrug-resistant microorganisms increasingly requires the use of last resort drugs, and new…
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Rare Case of Psychrobacter Sanguinis Bacteremia in a Homeless Patient with Thigh Phlegmon
Psychrobacter sanguinis is an emerging opportunistic pathogen predominantly isolated from cold environments that is increasingly recognized for its clinical relevance. This case report documents a rare instance of P. sanguinis bacteremia in a 69-year-old homeless patient presenting with thigh…
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Overview of Aga Genes and their Role in Utilization of N-Acetyl-D-Galactosamine and D-Galactosamine by Bacteria
Bacteria use a variety of mechanisms in order to successfully survive in hosts. To support proliferation sophisticated means of maintenance in host especially metabolism of carbon and nitrogen is needed. One metabolic mechanism is the metabolism of amino sugars which are being used simultaneously…
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Artikel Jurnal
Chemotherapy Resistance Status of Common Human Pathogenic Protozoa
Protozoal infections exert significant health, community, and economic impact globally, primarily in tropical and subtropical regions. Due to the absence or inefficacy of vaccines for deadly protozoal illnesses, chemotherapy is a primary means for preventing such diseases. Growing drug resistance…
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Artikel Jurnal
Narlx Two-Component Signaling System as a Key Mechanism of Bacterial Adaptation
The two-component NarLX signaling system is a key mechanism for bacterial adaptation to changing environmental conditions. Composed of a histidine kinase (NarX) and a response regulator (NarL), it enables bacteria to accurately detect and respond to environmental changes, particularly in nitrate…