280 results
Showing 1–20 · 0.65 seconds · RSS
J
ISSN 2571-8800 · MDPI AG · 280 articles in the index
-
Journal Article Full text
Nicotinamide Mononucleotide Suppresses α-MSH-Induced Melanogenesis via Downregulation of Tyrosinase in B16F10 Cells
Skin hyperpigmentation caused by excessive melanin production has led to increasing interest in the development of effective anti-melanogenic agents. In this study, the anti-melanogenic effects and underlying mechanisms of nicotinamide mononucleotide (NMN) were investigated using α-MSH-induced…
-
Journal Article Full text
Initial Development Through Serial Pilot Studies of the Pickleball Power and Placement Test
There are no widely used standardized tests of pickleball skill. The purpose of this research was to develop a test to represent general paddle-stroke ability via evaluation of the serve. This paper describes multiple phases of sequential exploratory research studies that iteratively developed the…
-
Journal Article Full text
Climate Changes and Socio-Economic Sustainability: A Case Study of the Roman Province of Dalmatia
The study of the conceptual framework examined climate change, water civilization, and socio-economic development in ancient Dalmatia (Croatia). The study examined the cultural and social development centered on managing and depending on water from 350 BCE to 900 CE. Significance was highlighted on…
-
Journal Article Full text
Generation Mean Analysis of Gene Action for Photosystem II Fluorescence Parameters in Two Bread Wheat Crosses
Chlorophyll fluorescence parameters are sensitive indicators of photosystem II (PSII) functionality and overall photosynthetic performance; however, their genetic architecture in wheat remains poorly understood. This study aimed to elucidate the gene action governing chlorophyll fluorescence traits…
-
Journal Article Full text
Machine Learning and Deep Learning for EEG-Based Dementia Prediction: A Comprehensive Survey
Dementia-related disorders, particularly Alzheimer’s disease (AD), represent a growing global health challenge, increasing the need for early and reliable detection. Electroencephalography (EEG), a non-invasive and cost-effective neurophysiological modality, has emerged as a promising tool for…
-
Journal Article Full text
Simultaneous Visual Detection of 12 Pathogenic Bacteria Based on Multiplex PCR-Gene Membrane Chip Technology
Rapid and accurate detection of pathogenic bacteria is of critical concern in the food and pharmaceutical sectors. In this study, a gene membrane chip detection method combining multiplex PCR with reverse dot blot hybridization was developed to enable visual, high-throughput simultaneous…
-
Journal Article Full text
Valorization of Oilseed Agro-Industrial Coproducts Through Optimized Lipase Production by Trichoderma sp. in Submerged Fermentation
This study integrates microbial biotechnology, bioprocess optimization, and circular bioeconomy principles to valorize oilseed agro-industrial coproducts as low-cost inducing substrates for lipase production. Palm kernel cake (PKC), canola cake, andiroba cake, and brewer’s spent grain were…
-
Journal Article Full text
Social Determinants of Health Analysis of Athletic Trainers’ Perspectives on Student-Athlete Food Security Constraints and Drivers: A Qualitative Study
Background: This study explored the observations and experiences of athletic trainers (ATs) regarding food security constraints and drivers among collegiate student-athletes through the framework of the social determinants of health (SDOH). Methods: Seventeen ATs from nine public Mountain West…
-
Journal Article Full text
Clinical Text De-Identification Beyond PHI Detection: A Scoping Review
Background: Removing explicit protected health information (PHI) does not necessarily make a clinical narrative non-identifiable. Rare diagnoses, social circumstances, locations, temporal patterns, and treatment trajectories may still permit re-identification. Methods: This PRISMA-ScR-informed…
-
Journal Article Full text
The Solution Structure of the Elenbaas–Heller Equation for Inductively Coupled Plasmas and Wall Stabilized Arcs
A numerical bifurcation analysis is presented for inductively coupled plasmas and wall-stabilized arcs for argon and hydrogen. Because of the non-linear transport and radiative properties, both problems admit multiple solutions, up to three for argon and up to four for hydrogen. The multiplicity…
-
Journal Article Full text
Comparison of Cyclic Triaxial Tests with Constant and Variable Cell Pressure
Cyclic triaxial tests are often used to evaluate the behavior of soils under seismic loads. The stress conditions imposed on a soil specimen during a cyclic triaxial test, however, are very different than those acting on an element of soil during an earthquake. One major difference is that the…
-
Journal Article Full text
Decoding the Shear Strength of Sand–Concrete Interfaces: The Role of Surface Texture and Bentonite
Bentonite slurry is frequently used as a support fluid in the construction of drilled shafts. During the piling process, the slurry acts as a sealant and slightly penetrates the nearby soil. However, the degree to which bentonite slurry penetrates the soil affects the resulting frictional capacity…
-
Journal Article Full text
Factors Associated with Frailty Risk Based on Admission Information Using Diagnosis Procedure Combination Data: A Single-Center Retrospective Study
Frailty is a geriatric syndrome associated with adverse outcomes, particularly in super-aged societies. Hospitalization-related inactivity may contribute to frailty progression and worsen prognosis and post-discharge quality of life; however, frailty identification at admission is challenging. This…
-
Journal Article Full text
Mechanistic Insights into Off-the-Shelf vs. Personalized mRNA Cancer Vaccines: A Comparative Review of BNT111 and BNT122
mRNA vaccines are a relevant approach in cancer immunotherapy, using messenger RNA to induce immune responses against tumor-associated antigens. In this review, BNT111 and BNT122 are compared as representative off-the-shelf and personalized models. BNT111 is a fixed mRNA vaccine that has…
-
Journal Article Full text
The Impact of Precision Livestock Farming Technologies on Productivity, Animal Welfare, and Environmental Sustainability
Precision Livestock Farming (PLF) has emerged as an approach in modern animal production, integrating advanced technologies such as sensors, automation, data analytics, and artificial intelligence to enable continuous, individualised monitoring of livestock and their environment. This review…
-
Journal Article Full text
Assessing Scaling Tendencies by Mixing Seawater and Aquifer Water in Reservoirs and Porous Media
Waterflooding in oilfields for oil displacement and reservoir pressure maintenance has led to the production of scale in several reservoirs. The formation of scale occurs both in the porous media of the reservoir and in the production equipment, leading to production disruptions that result in a…
-
Journal Article Full text
Mining Patient Narratives to Analyze Lifestyle–Blood Glucose Relationships: An LLM-Based Text Mining Framework
Lifestyle-related diseases such as diabetes are closely influenced by daily habits, yet the complex interactions between lifestyle factors and blood glucose variation remain insufficiently quantified. This study proposes a natural language processing (NLP) framework that analyzes long-form illness…
-
Journal Article Full text
Residual Dp71 Expression Is Sufficient to Preserve Retinal Vascular Homeostasis in a Mouse Model of Duchenne Muscular Dystrophy
The dystrophin gene encodes multiple dystrophin isoforms with tissue-specific functions, including several shorter isoforms expressed in the central nervous system and retina. While Duchenne muscular dystrophy (DMD) has historically been characterized as a primary myopathy resulting from loss of…
-
Journal Article Full text
CsPbI3 Perovskites at the Edge of Commercialization: Persistent Barriers, Multidisciplinary Solutions, and the Emerging Role of AI
All-inorganic cesium lead iodide (CsPbI3) has been investigated for more than a decade as an absorber for perovskite photovoltaics thanks to its attractive bandgap, thermal robustness compared with hybrid perovskites, and compatibility with tandem concepts. Yet, despite remarkable efficiency…
-
Journal Article Full text
Melt Damage and Prevention of Gas Nozzle Tip in Close-Coupled Gas Atomization
Gas atomization is one method for producing fine metal powder. In close-coupled gas atomization, a high-speed gas jet is ejected near the molten metal, and the molten metal is further broken down in the shear layer at the outer edge of the jet, producing fine metal powder of several micrometers to…