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Journal of Cutaneous Immunology and Allergy
Scopus
ISSN 2574-4593 · Frontiers Media S.A. · 325 articles in the index
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Journal Article
The epidemiological and clinical association between primary focal hyperhidrosis and various skin disease in Japanese patients: outpatient questionnaire analysis
Hyperhidrosis, defined as excessive sweating beyond physiological needs. It impairs the quality of life (QOL) of patients. While there are many studies on the relationship between sweating and skin diseases, however few studies have been conducted from epidemiological perspective of hyperhidrosis…
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Journal Article
Case Report: Sjögren’s disease diagnosed following generalized anhidrosis
Sjögren’s disease typically presents with initial symptoms such as dry mouth, dry eyes, fatigue, and joint pain. This report describes a case of Sjögren’s disease diagnosed following the onset of generalized anhidrosis. The patient had experienced anhidrosis and elevated body temperature for the…
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Journal Article
Cross-species gene expression analysis identifies a type I interferon-associated transcriptional signature in Tregs from atopic dermatitis
Although regulatory T cells (Tregs) maintain immune tolerance, disease-relevant Treg molecular states in atopic dermatitis (AD) remain unclear. This study used an inducible mouse model of spontaneous AD-like dermatitis caused by combined Foxp3 and Bcl6 gene deletion and established a bacterial…
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Journal Article
Pruritogenic mediators in atopic dermatitis: mechanisms of neurogenic crosstalk
Pruritus is the most burdensome and persistent symptom of atopic dermatitis (AD), often impairing quality of life more profoundly than visible skin inflammation. Emerging evidence indicates that itch in AD is not merely a downstream consequence of inflammation but an active disease driver that…
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Journal Article
Efficacy and safety of tapinarof cream once daily in Japanese pediatric patients with atopic dermatitis: a 60-week phase 3 trial consisting of an 8-week, double-blind, vehicle-controlled period and a 52-week, open-label extension period
BackgroundIn Japan, tapinarof cream (an aryl hydrocarbon receptor agonist) is approved for the treatment of atopic dermatitis (AD) in patients aged ≥12 years.MethodsIn Japanese pediatric patients aged 2–11 years with AD, we conducted a 60-week phase 3 trial of tapinarof cream, consisting of an…
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Journal Article
Antinuclear antibody positivity rate and clinical characteristics in prurigo chronica multiformis: a retrospective study of 26 patients
BackgroundPrurigo chronica multiformis is a refractory chronic pruritic dermatosis that predominantly affects older adults, but the frequency and significance of antinuclear antibody (ANA) positivity remain unclear.MethodsThis retrospective single-center study included 26 patients with prurigo…
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Journal Article
Case Report: Successful dupilumab treatment for refractory atopic dermatitis-like eczema in a patient with Costello syndrome
Costello syndrome is a rare RASopathy caused by pathogenic variants in HRAS and is characterized by distinctive craniofacial features, growth failure, cardiac abnormalities, tumor predisposition, and various cutaneous manifestations. Although eczema has been reported in patients with Costello…