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ACR Open Rheumatology
Scopus
ISSN 2578-5745 · Wiley · 957 artikel di indeks
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Artikel Jurnal
Associations Between Smartphone‐Derived Behavioral Data and Rheumatoid Arthritis Flares
Objective Rheumatoid arthritis (RA) features sporadic symptoms that intensify during flares, significantly affecting the quality of life. This study aimed to (1) characterize flare frequency and severity, (2) assess if short‐term changes in patient‐reported outcomes (PROs) signal RA flares, and (3)…
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Artikel Jurnal
Impact of Variation in APOE on Rheumatoid Arthritis, Psoriasis, and Psoriatic Arthritis: Sequencing and Genotyping in General Population Cohorts
Objective Emerging evidence suggests that apolipoprotein E (apoE) may be involved in the immune system and diseases driven by chronic inflammation. The impact of the full range of structural genetic variation in APOE for risk of rheumatoid arthritis, psoriasis, and psoriatic arthritis in the…
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Artikel Jurnal
Transitions in Psychological Distress Phenotypes and Patient‐Reported Outcomes Among Patients Undergoing Total Joint Arthroplasty
Psychological distress is common in individuals undergoing total joint arthroplasty (TJA). Understanding psychological phenotypes and their transitions from before to after surgery can inform risk stratification and targeted care. This study aimed to characterize psychological phenotypes, examine…
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Artikel Jurnal
Prevalence and Clinical Characteristics of Systemic Sclerosis in Alaska Native and American Indian Peoples in Alaska
Objective Systemic sclerosis (SSc) is known to exhibit significant epidemiologic and clinical variation. This study aimed to describe the clinical and epidemiologic characteristics of SSc in Alaska Native and American Indian (AN/AI) individuals in Alaska. Methods Adults with a potential diagnosis…
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Artikel Jurnal
Similar Pain Scores in Rheumatoid Arthritis and Osteoarthritis Over 45 Years Despite Dramatically Fewer Swollen Joints in Rheumatoid Arthritis: Are Scores Based as Much on Pain Sensitization and Patient Distress as on Inflammation and/or Structural Damage?
This narrative review presents five observations concerning 0 to 10 pain Visual Analog Scale (VAS)/Visual Numeric Scale (VNS) scores in routine care patients with primary diagnoses of rheumatoid arthritis (RA) or osteoarthritis (OA) over more than four decades: (1) Although median RA swollen joint…
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Artikel Jurnal
Outcomes of an Intravenous to Subcutaneous Infliximab (CT‐P13) Strategy in Takayasu Arteritis: A Proof‐of‐Concept Prospective Study
Objectives To evaluate persistence, outcomes, safety, and remission maintenance after switching from intravenous infliximab (IV‐IFX) to subcutaneous infliximab (SC‐IFX, CT‐P13) in patients with Takayasu arteritis (TA). Methods We conducted a prospective, single‐center, proof‐of‐concept…
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Artikel Jurnal
Computer‐Assisted Dynamic Contrast–Enhanced Magnetic Resonance Imaging Quantification Method for Assessment of Synovial Inflammation in Active Arthritis: Correlation With Synovial and Blood Biomarkers
Objective To investigate the correlation and association between dynamic contrast–enhanced magnetic resonance imaging (DCE‐MRI) quantification (DEMRIQ) parameters with local and systematic markers of inflammation in patients with various etiologies of acute knee arthritis. Methods In a…
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Artikel Jurnal
Rehabilitation Referral in Rheumatology: Insights From the RISE Registry
Objective The aim was to describe the percentage of patients with axial spondyloarthritis (axSpA), rheumatoid arthritis (RA), and systemic lupus erythematosus (SLE) in the Rheumatology Informatics System for Effectiveness (RISE) Registry who received a rehabilitation referral. Methods Data were…
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How Long Do People With Arthritis Stay Healthy and in Work? Analysis of Data From the Health and Retirement Study
Objective To estimate healthy working life expectancy (HWLE; the average number of years that adults from age 50 years can expect to be healthy and in paid work) in the United States for people with arthritis overall and by sex, education, ethnicity, region, and obesity status. Methods Longitudinal…
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Artikel Jurnal
Impaired Generation of High‐Affinity Memory B Cells and Neutralizing Antibodies Against SARS‐CoV‐2 in Adolescents and Young Adults With Juvenile Idiopathic Arthritis Treated With Tumor Necrosis Factor Inhibitors
Objective We evaluated the immunogenicity of SARS‐CoV‐2 mRNA vaccines in patients with juvenile idiopathic arthritis (JIA), focusing on the generation of spike‐specific memory B cells (MBCs) and of neutralizing antibodies, and assessed the impact of disease‐modifying antirheumatic drugs…
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Artikel Jurnal
Lymphocyte Activation Gene 3 Regulation of Profibrotic Cytokines and Type I Collagen Production in Patients With Systemic Sclerosis
Objective Diffuse cutaneous systemic sclerosis (dcSSc) is characterized by skin and internal organ fibrosis. The regulatory aspects of the immune system involved in maintaining tolerance are still poorly understood in dcSSc. The late checkpoint inhibitory lymphocyte activation gene 3 (LAG‐3) is…
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Artikel Jurnal
Clinical Characteristics and Evolution of Interstitial Lung Disease in Subtypes of Idiopathic Inflammatory Myositis With Prevalent Lung Manifestation: A Retrospective Analysis
Objective Interstitial lung disease (ILD) is common in idiopathic inflammatory myositis (IIM), particularly in antisynthetase syndrome (ASyS), antimelanoma differentiation‐associated protein 5 (anti‐MDA5) syndrome, and scleromyositis. ILD can progress despite resolution of extrapulmonary symptoms…
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Rheumatoid Arthritis Diagnostic and Monitoring Testing Patterns by Physicians and Advanced Practice Providers in the United States, 2012 to 2024
Objective To investigate longitudinal trends in rheumatoid arthritis (RA) diagnosis and monitoring by physicians and advanced practice providers (APPs) as measured by laboratory testing. Methods We conducted a retrospective review of RA‐associated diagnostic and monitoring tests ordered through…
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Discordance Between Patients and Physicians on Key Determinants of Systemic Lupus Erythematosus Burden: Insights From a French Comprehensive Survey
Objective To assess differences in perception between patients and physicians regarding the determinants of the burden of systemic lupus erythematosus (SLE) in France. Methods An online survey was conducted by IPSOS, a market research company, among adult patients with SLE and physicians…
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Artikel Jurnal
Considering Pregnancy: Duality in the Reproductive Journey and Decision‐Making in Hispanic Women With Systemic Lupus Erythematosus in the United States
Objective Systemic lupus erythematosus (SLE) commonly affects women during their childbearing years, making pregnancy experiences especially important to understand. This is particularly true for US Hispanic women, who face a higher SLE burden, more unplanned pregnancies, and frequent language or…
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Artikel Jurnal
Macrophage Activation Syndrome–Associated Proteins and Enhanced Interferon‐γ Responsiveness in the Plasma Proteome of Patients With Multisystem Inflammatory Syndrome in Children in a Pretreatment Replication Single‐Center Cohort
Objective Multisystem inflammatory syndrome in children (MIS‐C) is a rare hyperinflammatory syndrome that follows SARS‐CoV‐2 infection. Prior plasma proteomic analysis from a 2020 cohort of patients with MIS‐C at our center revealed a profile characterized by thrombotic microangiopathy (TMA)…