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Journal of Biosafety and Biosecurity
Scopus
ISSN 2588-9338 · KeAi Communications Co., Ltd. · 184 artikel di indeks
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Artikel Jurnal
Green-synthesised bimetallic nanomaterials: plant-derived solutions for antibacterial challenges
Background: Nosocomial pneumonia caused by multidrug-resistant (MDR) respiratory pathogens remains a major threat to patient safety and hospital biosafety, necessitating the development of sustainable and effective antimicrobial alternatives. Objective: This study aimed to synthesise and evaluate…
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Artikel Jurnal
Scientific and experimental assessment of the biosafety of a recombinant cytokine-producing strain as part of a biocorrective agent
Introduction: Recombinant probiotic microorganisms that express immunoregulatory proteins are considered promising tools for the local correction of inflammatory bowel diseases. However, their practical application requires a comprehensive biosafety assessment, including an analysis of…
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Artikel Jurnal
Foundation of biosecurity education: biosecurity glossary
Background: One of the persistent challenges in biosecurity education is the lack of common vocabulary among key stakeholders − including scientists, educators, policymakers, diplomats, regulators, industry actors, and civil society − which can hinder effective communication, awareness-raising, and…
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Artikel Jurnal
Strategies to strengthen biosecurity regulation in the ASEAN region and the United States: Approaches and implications
The rise of biological threats, such as new infectious diseases, including coronavirus disease (COVID-19), bioterrorism and unregulated biotechnology use, shows that it is critical for the Association of Southeast Asian Nations (ASEAN) region to have strong biosecurity laws, especially to safeguard…
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Mirror-image biology: perspectives and challenges
Mirror-image biology is an emerging frontier in synthetic biology that uses chirally inverted biomolecules—D-proteins and L-nucleic acids—to construct orthogonal biological systems. Rapid advances in biomedicine, bioengineering, environmental protection and information technology underscore the…
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Artikel Jurnal
Regulating synthetic biology and advanced genetic interventions: biosecurity frameworks, gene therapy oversight, stem-cell manufacturing risks and future policy directions
Gene editing (CRISPR-Cas9, base and prime editing), viral-vector therapies (adeno-associated virus [AAV] and lentiviral systems) and engineered stem cell platforms (induced pluripotent stem cells and mesenchymal lines) have transformed disease treatment but also introduced profound biosafety risks…
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Bioinformatic assessment of the potential for harm to humans via horizontal gene transfer from the planned release of genetically modified mosquito vectors
Genetic biocontrol is a novel strategy that may one day be used to combat the spread of invasive species and infectious diseases. A comprehensive assessment of potential ecological and human health risks was recently completed for a proposed field study of Anopheles coluzzii mosquitoes genetically…
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Artikel Jurnal
Mathematical analysis and numerical simulation of campylobacteriosis dynamics: assessing the roles of house flies and contaminated food products as mechanical vectors
Globally, food-borne campylobacteriosis is a major cause of bacterial gastroenteritis, disproportionately affecting impoverished areas. Inadequate sanitation infrastructure in these settings leads to abundant house flies, potentially contaminating food and surfaces and increasing the spread of…
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Design, establishment and accreditation of biosafety Level 3 laboratory using the Egyptian experience for sustainable high-containment capacity in national biological defence structure
BSL-3 laboratories are crucial for global health security because they provide a basis for the research and diagnostics of new and known infectious agents. Yet few such facilities have been established, and those that do exist struggle to remain due to technical, regulatory and financial…
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Artikel Jurnal
Exploring the photodynamic antifungal efficacy and mechanism of red-emissive carbon dots
Carbon dots (CDs), a rapidly emerging class of carbon-based nanomaterials with exceptional photophysical properties and excellent biocompatibility, have demonstrated significant potential in the biomedical field, particularly in photodynamic therapy (PDT). Given that fungi exhibit…
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Artikel Jurnal
Integrated assessment of biosafety, biosecurity and cyber-biosecurity in clinical microbiology laboratories in Lubumbashi, Democratic Republic of the Congo
Clinical microbiology laboratories in low-resource settings face increasing biological and digital risks, yet integrated evaluations of biosafety, biosecurity and cyberbiosecurity remain scarce in sub-Saharan Africa. This study assessed the operational profiles of laboratories in Lubumbashi…
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Optimal strategies for containing infectious disease spread in mass gatherings with crowd mobility
The risk of infectious diseases is considerably high during Hajj rituals due to overcrowding. The general application of a framework that describes Hajj can be limited as the characteristics of mass gatherings differ from one site to another. Therefore, there is a call for studies that focus on…
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Artikel Jurnal
Estimating the time-varying effectiveness of COVID-19 preparedness in WHO European Region: A biorisk-focused wavelength (BFW) model approach
This study analyses how the time-varying predictive power of national preparedness capacities over the impact of the coronavirus disease 2019 (COVID-19) pandemic has changed over time. Building on the ‘preparedness paradox’ in the literature, the hypothesis that preparedness is a dynamic process…
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Artikel Jurnal
New methods for the assessment and prediction of vector-borne infectious diseases
This study, which demonstrates that the single-population Susceptible-Exposed-Infectious-Recovered (SEIR) model is also applicable to the assessment and prediction of vector-borne infectious disease outbreaks, provides a reliable model tool for the future prevention and control of vector-borne…
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Artikel Jurnal
Patent-based analysis of biosafety trends in synthetic biology
This study explored biosafety trends in synthetic biology through patent analysis. As an interdisciplinary field, synthetic biology brings innovation opportunities to society, but it is accompanied by risks, such as the leakage of biological materials and genetic contamination. The Derwent…
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Artikel Jurnal
Forecasting tuberculosis prevalence in Afghanistan until 2032: a mathematical modelling analysis
Background: Accurate disease forecasting can inform public health policies. Nonetheless, many countries, including Afghanistan, have yet to learn from this exercise. Objectives: This study aimed to forecast tuberculosis (TB) prevalence in Afghanistan until 2032 and to estimate the reproduction…
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Artikel Jurnal
Medical students’ mobile phones: hotspots for antimicrobial-resistant Gram-negative bacteria
Introduction: The mobile phones (MPs) of medical personnel can be easily and rapidly contaminated by bacteria from patients or medical devices and by medical school or hospital environments. This is the first study set in Aljouf Province, Saudi Arabia, to assess the prevalence of bacterial…
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Artikel Jurnal
Hepatitis B virus S gene substitutions in Iraqi patients: computational analysis of missense substitutions and functional impact
Background: The hepatitis B virus (HBV) continues to be a global health concern, with immune-escape substitutions increasingly reported in regions where genotype D predominates. In Iraq, where genotype D is the dominant strain, the functional impact of naturally occurring S gene substitutions…