244 results

Current state of endovascular treatment for cavernous and petrous internal carotid artery aneurysms

Jinlu Yu

Brain Hemorrhages, Vol. 7 No. 5 · 2026 · English · DOAJ Scopus

Cavernous and petrous internal carotid artery (ICA) aneurysms have similar clinical characteristics, making it feasible to discuss these two types of aneurysms together. Currently, endovascular treatment (EVT) is favorable for these lesions. However, EVT techniques are complex. A review is…

Effectiveness of 3D printed and mixed reality models in neurosurgical patient education: A systematic review

Stefanie Bauer; Joshua Haegler; Debora Cipriani et al.

Brain Hemorrhages, Vol. 7 No. 5 · 2026 · English · DOAJ Scopus

Objective: Neurosurgical patients often face psychological distress due to difficulty understanding their medical condition and treatment plan. Traditional educational tools like MRI or CT scans may not effectively convey this information. 3D-printed models and mixed reality (MR) devices have…

Ngn2 failed to induce astrocyte-to-neuron reprogramming after intracerebral hemorrhage

Shiling Chen; Liyang Huang; Jingyi Wang et al.

Brain Hemorrhages, Vol. 7 No. 5 · 2026 · English · DOAJ Scopus

Objective: Intracerebral hemorrhage (ICH) is a severe neurological disorder with high mortality due to neuronal loss, and current therapies face significant challenges. Cell reprogramming offers a potential solution. This study explores whether Neurogenin2 (Ngn2) can reprogram astrocytes into…

A study on the relationship between the severity of leukoaraiosis and post-thrombolytic hemorrhage in acute cerebral infarction thrombolysis patients

Wei Zhou; Chen Li; Xiaoling You et al.

Brain Hemorrhages, Vol. 7 No. 5 · 2026 · English · DOAJ Scopus

Objective: This study aims to investigate the relationship between the severity of leukoaraiosis and post-thrombolytic intracerebral hemorrhage (ICH) in patients with acute cerebral infarction undergoing thrombolytic therapy. It also analyzes the characteristics of cases involving ICH after…

Microglia-neuron crosstalk in intracerebral hemorrhage: from neuroimmunomodulation to neurorepair

Qingli Wang; Yun Chen; Xuelong Liu et al.

Brain Hemorrhages, Vol. 7 No. 5 · 2026 · English · DOAJ Scopus

Intracerebral hemorrhage (ICH) remains a devastating disease with high mortality and disability rates, yet effective therapeutic strategies are still limited. Emerging evidence has highlighted that the dynamic crosstalk between microglia and neurons plays a central role in both secondary brain…

Beyond recanalisation: The ATTRACTION trial shows a promising role for tirofiban after successful thrombectomy

Xuewei Xie; Zeguang Ren; Yongjun Wang

Brain Hemorrhages, Vol. 7 No. 5 · 2026 · English · DOAJ Scopus

Despite successful thrombectomy, many patients with large-vessel occlusion stroke remain functionally dependent. The ATTRACTION trial evaluated low-dose tirofiban after successful endovascular reperfusion and showed a modest improvement in 90-day functional independence without a statistically…

CORM-2 attenuates red blood cell-mediated inflammation by upregulating phagocytic capacity of cerebral microglial cells of the neonatal rat

Zhiying Chen; Huiyan Zhang; Jun Zhou et al.

Brain Hemorrhages, Vol. 7 No. 5 · 2026 · English · DOAJ Scopus

Objective: To explore the mechanism of CORM-2 on attenuating hemorrhage-related inflammation. Methods: Microglia were isolated from neonatal rats (1–2 days old) and identified using CD11b/c antibody. Subsequently, some of the microglia were co-cultured with red blood cells (RBCs) marked with PKH26…

Dual-port robot-assistant visualized minimally invasive aspiration (RAVMIA) for evacuation of irregular basal ganglia hemorrhage: A technical note

Huachao Li; Zhenyu Luo; Tingzhong Wang

Brain Hemorrhages, Vol. 7 No. 4 · 2026 · English · DOAJ Scopus

Background: The surgical management of intracerebral hemorrhage (ICH) remains controversial. While minimally invasive endoscopic techniques have shown promise, recent trials have not demonstrated positive outcomes for deep-seated basal ganglia hemorrhages. Although we previously reported a novel…

Oxidative stress in post-stroke neurorestoration: from mechanisms to therapy

Pingping Guo; Lingxiao Qi; Voon Wee Yong et al.

Brain Hemorrhages, Vol. 7 No. 4 · 2026 · English · DOAJ Scopus

Reversible cerebral vasoconstriction syndrome: not just a “reversible” condition. Retrospective observational study and literature review

Joumana Freiha; Ardalan Zolnourian; Aung Oo et al.

Brain Hemorrhages, Vol. 7 No. 4 · 2026 · English · DOAJ Scopus

Objectives: This study aims to critically evaluate the evolving understanding of reversible cerebral vasoconstriction syndrome (RCVS) by examining its potential for long-term complications. While reversible cerebral vasoconstriction syndrome (RCVS) is traditionally recognised as a monophasic…

Development and validation of an improved ICH score: Integrating clinical and radiographic parameters for enhanced prediction of 30-day mortality in spontaneous intracerebral hemorrhage

Pichayen Duangthongphon; Amnat Kitkhuandee; Pornthep Kasemsiri et al.

Brain Hemorrhages, Vol. 7 No. 4 · 2026 · English · DOAJ Scopus

Objective: The ICH score effectively predicts 30-day mortality in patients with intracerebral hemorrhage (ICH), but accuracy decreases in surgical cases. This study evaluated whether integrating clinical and radiographic parameters with the original ICH variables enhances mortality prediction…

Efficacy and safety of middle meningeal artery embolization in combination with burr hole craniostomy for chronic subdural hematomas: A single-center experience

Jiandong Wu; Peng Deng; Jinhong Qian et al.

Brain Hemorrhages, Vol. 7 No. 4 · 2026 · English · DOAJ Scopus

Background and Objective: Chronic subdural hematoma (CSDH) is a prevalent neurosurgical condition. The mass effect of hematoma could lead to a series of neurological dysfunctions. Surgical intervention, such as burr hole craniostomy (BHC), is often recommended due to persistent symptoms, but…

Machine learning-based radiomics model for predicting hematoma enlargement in spontaneous intracerebral hemorrhage: A multicenter study

Jianlong Ouyang; Wei Xu; Xianting Luo et al.

Brain Hemorrhages, Vol. 7 No. 4 · 2026 · English · DOAJ Scopus

Objective: This study aimed to establish and validate three predictive models: a clinical model (CM), a radiomics model (RM), and a combined clinical–radiomics model (CRM) for forecasting hematoma progression in patients with spontaneous intracerebral hemorrhage (sICH) within 24 h of admission…

Comparison of single-channel EEG decoding performance in imagined speech tasks

Xinyu Ma; Yibo Ding; Kunyuan Zhao et al.

Brain Hemorrhages, Vol. 7 No. 2 · 2026 · English · DOAJ Scopus

Objectives: Electroencephalography (EEG)-based imagined speech decoding technology offers a communication solution for patients with language impairments. However, existing research on English-language systems cannot be directly applied to Chinese due to significant linguistic differences…

Prognostic value of TC/HDL-C ratios in ischemic stroke: a multicenter observational study

Hang Ruan; Qin Zhang; Ping Zhang et al.

Brain Hemorrhages, Vol. 7 No. 2 · 2026 · English · DOAJ Scopus

Objective: This study aimed to determine the relationship between the total cholesterol to high-density lipoprotein cholesterol (TC/HDL-C) ratio and adverse outcomes in patients with first-ever ischemic stroke (IS), and to validate its potential as a prognostic indicator. Methods: A dual-cohort…

Sleep Disordered Breathing in Intracerebral Hemorrhage Survivors in Japan: a Meta-analysis and Systematic Review

Farhan Ishaq

Brain Hemorrhages, Vol. 7 No. 2 · 2026 · English · DOAJ Scopus

Objective: We evaluated the prevalence and correlates of sleep-disordered breathing (SDB) in intracerebral hemorrhage (ICH) survivors in Japan. Methods: A systematic search of PubMed, Scopus, CINAHL, and Clinicaltrials.gov through April 1, 2020 identified studies reporting prevalence and severity…

Inflammatory biomarkers in patients with intracranial aneurysms

Yu Xie; Xuefei Li; Zhiyuan Yu et al.

Brain Hemorrhages, Vol. 7 No. 2 · 2026 · English · DOAJ Scopus

Objective: Intracranial aneurysm (IA) is a serious cerebrovascular disease. This study aimed to investigate the clinical characteristics and plasma biomarkers associated with IA. Methods: A total of 207 participants were enrolled: 45 with unruptured IA, 95 with ruptured IA, and 67 controls…

Perioperative management of brain hemorrhage: Advances in anesthetic strategies and translational medicine

Meenaloshini Gopalakrishnan; Karthikeyan Elumalai; Nandhini Jayaprakash

Brain Hemorrhages, Vol. 7 No. 2 · 2026 · English · DOAJ Scopus

Brain hemorrhage, which encompasses intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH), poses significant challenges in perioperative management. Despite advances in neurocritical care, patient outcomes remain suboptimal, emphasizing the need for optimized anesthetic strategies and…

The role of blood lipid and triglyceride‑glucose index in intracranial aneurysms: A retrospective study

Xingwei Lei; Yajun Zhu; Liuyang Tang et al.

Brain Hemorrhages, Vol. 7 No. 2 · 2026 · English · DOAJ Scopus

Objective: The association between blood lipids and aneurysmal subarachnoid hemorrhage (aSAH) remains uncertain, with current research yielding conflicting results. Limited studies have explored the link between the triglyceride-glucose (TyG) index and the prognosis of subarachnoid hemorrhage. In…

Atorvastatin and glucocorticoid therapy for retroclival epidural hematoma: Case report and literature review

Chenrui Wu; Tao Liu; Ruichen Zhao et al.

Brain Hemorrhages, Vol. 7 No. 2 · 2026 · English · DOAJ Scopus

Retroclival epidural hematomas (REDH) are particularly rare conditions. We report for the first time the effect of conservative treatment of this rare condition with atorvastatin and glucocorticoids and review the literature. In this case, atorvastatin and glucocorticoid therapy can promote…