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Epilepsy & Behavior Reports
Scopus
ISSN 2589-9864 · Elsevier · 526 artikel di indeks
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Artikel Jurnal
Duolingo-induced seizures in GAD65 IgG associated autoimmune epilepsy
Autoimmune etiologies of seizures have been increasingly recognized with the discovery of novel autoantibodies to cell surface and intracellular antigens. GAD65 neurologic autoimmunity has been associated with stiff person syndrome, cerebellar ataxia, and chronic focal epilepsy, usually of temporal…
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Artikel Jurnal
Influence of cannabis use on length of stay in patients admitted to the epilepsy monitoring unit
Purpose: Epilepsy affects approximately 50 million people worldwide, many of whom undergo evaluation in Epilepsy Monitoring Units (EMUs) for seizure classification, medication management, or presurgical assessment. With increasing numbers of states legalizing marijuana use, a growing number of EMU…
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Artikel Jurnal
Interictal focal epileptic discharges in a pediatric patient with absence status epilepsy: a mimicker of focal epilepsy
Absence status epilepsy (ASE) is a rare generalized epilepsy that usually manifests in adolescence or adulthood, although pediatric-onset cases have also been described. It is characterized by recurrent episodes of absence status epilepticus, presenting as prolonged confusion or unresponsiveness…
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“I’m lonely”: An underrecognized marker of silent suffering in PWE in underresourced settings?
Loneliness is increasingly recognized as a significant psychosocial determinant of health, yet it remains comparatively underexplored in the context of epilepsy, and particularly in under-resourced environments. Unlike depression or anxiety, loneliness is less specifically sought, nor readily…
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Bloodletting as a harmful and misguided first-aid response to seizures in sub-saharan Africa: a case-based review
Epileptic seizures are common neurological events whose sociocultural interpretations have long been linked to supernatural causes or biomagico-symbolic beliefs. Depending on the region, blood may be regarded as the cause, seat, vector of evil, or even a therapeutic agent. These misconceptions…
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Factors associated with epileptiform discharges in patients visiting a memory clinic: A retrospective study
Epilepsy is a common comorbidity in older adults, particularly those with neurodegenerative diseases such as Alzheimer’s disease. However, recognizing epilepsy in patients with dementia can be challenging, as its symptoms often mimic cognitive fluctuations. Reliable clinical indicators validated by…
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Association of depression and epilepsy in rural northern Rwanda: a prospective longitudinal study with a patient-centered approach
Introduction: Depression is the most frequent co-morbidity in persons living with epilepsy (PwE). In Rwanda, the prevalence of epilepsy ranges between 2.9 and 7.6% and the prevalence of any depression in PwE is more than 22%. This prospective interventional patient-centered study determined…
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Artikel Jurnal
Drug-resistant epilepsy in an autosomal recessive copper metabolism disorder from SLC33A1 mutation
SLC33A1 mutation (Huppke-Brendel Syndrome) is a rare, autosomal recessive disorder associated with copper metabolism and characterized by global developmental delay, sensorineural hearing loss, congenital cataract and generalized hypotonia. We report two siblings under 6 years with novel SLC33A1…
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Status epilepticus as a novel etiology of Lance–Adams syndrome: a case report
Lance–Adams syndrome (LAS) is a rare neurological disorder characterized by action myoclonus. The majority of reported cases have occurred following resuscitation from cardiopulmonary arrest, and to our knowledge, no previous case has been documented in the setting of status epilepticus. In this…
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Financial and clinical impact of clinical pharmacist practitioner-led follow-up in a VA epilepsy clinic
Background: Epilepsy is a chronic neurologic condition that requires specialist follow-up and frequent medication adjustments. A multidisciplinary Veterans Affairs (VA) clinic model was implemented in which clinical pharmacist practitioners (CPPs) provide follow-up care under epileptologist…
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Artikel Jurnal
Fenfluramine for seizures in Dravet syndrome and Lennox-Gastaut syndrome: Mechanisms, clinical evidence, safety, and practical integration
Developmental and epileptic encephalopathies such as Dravet syndrome and Lennox–Gastaut syndrome remain highly drug resistant and are associated with substantial neurodevelopmental, behavioral, and caregiver burdens. Fenfluramine, repurposed at low antiseizure doses, is approved as adjunctive…
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Lived experiences of young people with epilepsy in a resource-constraint setting: Contemporary findings from Cape Coast, Ghana
Epilepsy is a chronic neurological condition that affects millions of young people globally, often leading to physical, cognitive, psychological, and social challenges. In resource-constraint settings, access to healthcare and medications, stigma, and psychosocial burdens can further exacerbate the…
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Artikel Jurnal
Chorea–athetosis-like hyperkinetic seizures in temporal lobe epilepsy: insights from stereo-EEG in three patients
Purpose: To characterize the clinical and electrographic features of temporal lobe epilepsy (TLE) presenting with chorea–athetosis-like hyperkinetic seizures and to delineate the underlying seizure network using stereo-electroencephalography (SEEG). Methods: We retrospectively reviewed 102…
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Seizure freedom after vagus nerve stimulation in a patient with
Genetic-based epilepsies often present as distributed neural network disorders, challenging traditional focal versus generalized classifications. We report a 20-year-old male with drug-resistant epilepsy associated with a previously unreported SCN3A missense variant (c.5970C > G; p.Ser1990Arg)…
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Comparative trends in idiopathic epilepsy burden in China and worldwide based on Global Burden of Disease Study 2021
Background: Idiopathic epilepsy, defined by the absence of identifiable structural or metabolic etiologies, remains a significant contributor to the global neurological disease burden. However, long-term comparisons between China and the global level are limited. This study analyzed and compared…
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Comparison of selective amygdalohippocampectomy and anterior temporal lobectomy for mesial temporal lobe epilepsy: a systematic review and meta-analysis
Background: Anterior temporal lobectomy (ATL) and selective amygdalohippocampectomy (SAH) are the two most widely adopted surgical approaches for drug-resistant mesial temporal lobe epilepsy (MTLE). Although both procedures target seizure control, they differ in extent of resection and potential…
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Everolimus initiated in the neonatal period for refractory seizures associated with tuberous sclerosis complex: long-term clinical outcome
Objective: Everolimus is an established therapy for tumor manifestations and refractory focal seizures in tuberous sclerosis complex (TSC) in patients aged ≥2 years. Evidence regarding its use during the neonatal period, particularly for seizure control, remains extremely limited. Methods: We…
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The electroclinical phenotype of epilepsy following autoimmune encephalitis
Objective: To describe the temporal and spatial dynamics of electroencephalographic (EEG) recordings in epilepsy following autoimmune encephalitis (AE) compared to temporal lobe epilepsy (TLE) without signs of inflammatory etiology. Methods: We assessed electroencephalographic properties using…
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Artikel Jurnal
Expanding the phenotypic Spectrum of ZNF711: Autism and epilepsy in two siblings
Zinc Finger Protein 711 (ZNF711) is a Krüppel-type zinc finger transcription factor highly expressed in the brain and whose mutations have been associated with neurodevelopmental disorders such as intellectual disability, autism spectrum disorder, and epilepsy. While most pathogenic variants…
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Lived experiences that influence the quality of life among patients with epilepsy at Mulago National Referral Hospital
Background: In Uganda, the quality of life (QoL) of patients with epilepsy (PWE) remains poor due to clinical, psychological, and social challenges. While several quantitative studies have documented correlates of poor QoL in Ugandan PWE, the specific mechanisms, contextual meanings, and…