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Smart Materials in Medicine
Scopus
ISSN 2590-1834 · KeAi Communications Co., Ltd. · 208 artikel di indeks
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Artikel Jurnal
Transduction strategies in enzyme-free nanomaterial-based aptasensors for tetracycline antibiotics: A review
Enzyme-free aptamer-based biosensors have gained increasing attention for tetracycline monitoring, yet existing studies remain highly fragmented across materials and sensing formats. This review presents a mechanistic framework that systematically classifies optical and electrochemical aptasensors…
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Artikel Jurnal
Macrophage membrane-camouflaged nanoparticles as emerging therapeutics in metabolic dysfunction-associated steatotic liver disease
Chronic liver disease (CLD) is a major global health burden, with metabolic dysfunction-associated steatotic liver disease (MASLD) as a primary contributor through its promotion of persistent inflammation, fibrotic transformations, and increased cancer risk. Current therapeutic strategies remain…
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Chiral noble-metal nanomaterials: Chiral origins and biomedical applications
Chirality is a fundamental property in nature, and the rapid progress of nanoscience has enabled the design and fabrication of nanoscale materials with precisely controlled chiral architectures. These chiral nanostructures exhibit unique optical, catalytic, and sensing characteristics. Among them…
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Artikel Jurnal
Smart DNA nanocages mitigate oxidative stress and guide bone immune microenvironment for osteoporotic jawbone regeneration
Jawbone regeneration in osteoporotic patients remains a formidable challenge due to excessive reactive oxygen species (ROS), dysregulated bone immunity, and compromised osteogenic capacity. While nanomaterial-based modulation of the bone microenvironment has emerged as a promising therapeutic…
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Artikel Jurnal
Polyphenol–metal self-catalyzed conductive hydrogel enhances implant–tissue integration for bone regeneration
Artificial rigid scaffolds offer mechanical support and show potential for bone regeneration, yet their clinical application is often hindered by poor integration at the implant-bone interface and an inability to modulate the impaired electrophysiological microenvironment. Herein, we propose a…
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Artikel Jurnal
Integrating siRNA targeting PKM2 with photodynamic therapy to induce tumor energy collapse
Tumor cells exhibit an exceptionally high demand for energy to sustain uncontrolled proliferation and predominantly rely on glycolysis, rendering them vulnerable to energy-targeting interventions. However, metabolic plasticity often enables adaptive compensation, thereby limiting the efficacy of…
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Artikel Jurnal
Dual-antibacterial nano-sheet synergizes resveratrol delivery for burn regeneration
In the field of burn treatment, where infected wound sites face critical challenges such as inadequate antimicrobial efficacy and impaired tissue regeneration, developing multifunctional strategies that synergize antibacterial activity and regenerative promotion remains an urgent need. Here, we…
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Artikel Jurnal
Advanced nanomaterials for myocardial ischemia-reperfusion injury: Bridging precision imaging to targeted therapy
Myocardial ischemia-reperfusion injury (MIRI) is a major cause of heart failure, driven by oxidative stress, inflammation, and rapid loss of cardiomyocytes. Traditional therapies for MIRI remain limited, largely due to poor cardiac targeting and an absence of real-time diagnostic capabilities…
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Artikel Jurnal
Plant-derived exosome-like nanoparticles as promising biotherapeutic tools: recent advances and challenges
Exosomes, naturally occurring extracellular vesicles with diameters of 30–150 nm, have been extensively characterized in mammalian systems. In contrast, plant-derived exosome-like nanoparticles (PELNs) are emerging as versatile therapeutic carriers, offering distinct advantages including…
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Artikel Jurnal
Nanoparticles in cancer therapy: Strategies to penetrate and modulate the tumor microenvironment – A review
Despite advances in conventional cancer treatments such as surgery, chemotherapy, and radiation, these approaches still face significant challenges, including systemic toxicity, limited tumor specificity, and therapy resistance. These limitations highlight the need for more effective, targeted…
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Artikel Jurnal
Engineered gold nanoparticle-based miRNA precision regulation for tumor diagnosis and synergistic therapy
Cancer remains a major global health challenge, with traditional therapies such as chemotherapy, radiotherapy, and surgery often limited by side effects, drug resistance, and incomplete tumor eradication. Recent advances in molecular biology have highlighted the dual role of microRNAs (miRNAs) in…
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Artikel Jurnal
Two-dimensional materials for anti-inflammatory applications
Due to unique physicochemical properties including high surface-to-volume ratio, abundant active sites, and tunable surface functionalities, two-dimensional (2D) materials have emerged as an intriguing platform for anti-inflammatory therapy. This review comprehensively explores the physicochemical…
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Revolutionizing high altitude cerebral edema management: nanotechnology-enabled diagnostics and targeted drug delivery
Due to the increasing commercial activities and adventure travels, millions of people visit high-altitude regions every year. A rapid increase in altitude results in high-altitude cerebral edema (HACE), an acute form of HAI characterized by altered mental status and ataxia, which necessitates…
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A review on the applications of machine learning in biomaterials, biomechanics, and biomanufacturing for tissue engineering
In recent years, machine learning, a powerful data analysis and modeling technique, is continuously revolutionizing the field of tissue engineering. Its ability to learn and extract information from complex datasets opens up new opportunities for the development of tissue engineering. In this…
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Artikel Jurnal
Recent advances in shape memory polymers for biomedical applications: Bridging macro- and micro-scale effects
Shape memory polymers (SMPs) are a class of materials capable of undergoing deformation in response to external stimuli, and their unique shape-changing properties offer vast potential for applications in the biomedical field. Based on the dimensionality of the shape memory effect (SME)…
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Artikel Jurnal
Advanced oxygen therapeutics for treatments of acute hemorrhagic shock and organ preservation
Oxygen (O2) is vital in respiratory process that maintains biological balance in mammals. O2 therapeutics treat ischemic tissues by facilitating O2 transport and alleviating cellular hypoxia. The development of O2 carriers focuses on their interactions with molecular O2 to achieve therapeutic…
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Artikel Jurnal
Nanofiber membrane-foam composite sheet with dual pH-responsive functions of drug release and color change
Chronic wound repair remains challenging in skin regenerative medicine due to complex pathology and dynamic microenvironments. Traditional single-functional dressings fail to integrate exudate management, pH-responsive drug delivery, and inflammation monitoring, while empirical replacement disrupts…
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Artikel Jurnal
The cell-loaded alginate microspheres in cell culture and disease treatment
Due to the properties of biocompatibility, affordability, and high-throughput production capabilities, alginate-based biomaterials have been extensively studied in the biomedical field, which can be developed into scaffolds, hydrogels, and microspheres. To date, alginate microspheres encapsulating…
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Artikel Jurnal
Light-responsible ECM-mimetic scaffolds for neural differentiation. Intracellular versus extracellular photothermal stimulation
The development of approaches and materials that combine several types of stimulatory effects on nerve tissue growth is a promising task for biotechnology. The aim of this work was a comparative study of the influence of intracellularly and extracellularly localized polydopamine-containing…
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Artikel Jurnal
The cardiac electrophysiology-inspired patches for repairing myocardial infarction: A review
Myocardial infarction has been a serious threat to human health due to its high morbidity and mortality all over the world. The major problem is the loss of limited regenerative cardiomyocytes and occurrence of inflammatory response, leading to the formation of non-contractile and non-conducting…