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Biomolecular and Health Science Journal
ISSN 2620-8636 · Wolters Kluwer – Medknow Publications · 110 artikel di indeks
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Artikel Jurnal
Challenging Penile Reconstruction in Adult Balanitis Xerotica Obliterans with Near-total Glans Fibrosis
Balanitis xerotica obliterans (BXO), the genital manifestation of lichen sclerosus, is a chronic inflammatory dermatosis that may cause progressive sclerosis and anatomical distortion. This case report presents a 58-year-old male with a 2-year history of penile deformity, circumferential…
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Simultaneous Right Coronary Total Occlusion and Aortoiliac Revascularization: A Single-session Endovascular Strategy in an Octogenarian STEMI Patient
Severe aortoiliac occlusion can complicate device placement during primary percutaneous coronary intervention (PCI). This presents additional challenges when immediate coronary management is required. We report a single-stage endovascular approach to restore vascular access and achieve complete…
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Gut Dysbiosis in Tuberculosis Patients with Malnutrition: A Literature Review
Tuberculosis (TB) remains an international health burden with high morbidity and mortality, especially in low- and middle-income countries. Weight loss and malnutrition often coexist with TB and are linked to poor prognosis. Literature review based on TB, malnutrition, changes of gut microbiota…
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A One-group Pretest–Posttest Study: Effect of Initial Peripartum Cardiomyopathy Screening Training on Knowledge among Multidisciplinary Primary Healthcare Professionals in East Java, Indonesia
Introduction: Peripartum cardiomyopathy (PPCM) is a rare but serious cardiac condition that occurs in pregnant or postpartum women, characterized by impaired and decreased left ventricular ejection fraction
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A Case Report of Amphotericin B-Induced Recurrent Hypokalemia Complicating Cryptococcal Meningoencephalitis in a HIV Patient
Cryptococcal meningoencephalitis is a severe opportunistic infection in people with HIV. We report a 42-year-old man presenting with significant weight loss, neurological symptoms, and progressive vomiting. Neuroimaging and positive cryptococcal antigen testing in cerebrospinal fluid confirmed the…
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Unintended Consequence – Iatrogenic Acute Pericarditis Following Right Ventricular Perforation by Temporary Pacemaker Lead in Total Atrioventricular Block
Acute pericarditis is an uncommon but clinically significant complication of cardiac instrumentation that requires prompt recognition. This report describes a 48-year-old male with total AV block (TAVB) who developed iatrogenic acute pericarditis due to right ventricular (RV) perforation caused by…
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Association of Quick of Blood on Leukocyte Levels in Patients with Chronic Kidney Disease Who Undergo Regular Hemodialysis: A Retrospective Study
Introduction: Increasing the number of patients with chronic kidney disease (CKD) affects the required hemodialysis, whereas their clinical condition is determined by the uremic toxin in the circulating blood. These conditions were one of the quick of blood (Qb) in the dialysis process, which…
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Unfolding the Hidden: Indirect Culotte Stenting in a Parallel Left Anterior Descending Artery System for Chronic Total Occlusion – A Challenging Percutaneous Coronary Intervention
Chronic total occlusion (CTO) is a technically challenging lesion, and coronary variants such as a parallel left anterior descending (LAD) artery can obscure the target vessel. Parallel LAD is a rare congenital variant that can complicate interpretation when coexisting with CTO. Herein, the case of…
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Serum Transforming Growth Factor-β1 and Connective Tissue Growth Factor in Relation to Cardiac Remodeling and Lipid Profile in Hypertensive Adults
Introduction: Cardiac remodeling is significantly influenced by hypertension, but the relationship between circulating profibrotic biomarkers and structural cardiac changes in adult hypertensive patients remains insufficiently understood. Studies simultaneously evaluating serum transforming growth…
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Clinical Effectiveness and Safety of Stem Cell Therapy in Type 1 Diabetes Mellitus: A Systematic Review and Meta-analysis
Introduction: Type 1 diabetes mellitus (T1DM) represents an autoimmune disorder characterized by progressive deterioration of pancreatic β-cell through T-cell activity, which causes prolonged dependence on insulin. Meanwhile, stem cell treatment (SCT) is presently under investigation as a possible…
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Recognizing Lues Maligna in Human Immunodeficiency Virus-positive Individuals
Lues maligna is an uncommon manifestation of secondary syphilis that occurs primarily in immunocompromised individuals, particularly those with human immunodeficiency virus infection. Its clinical resemblance to opportunistic infections and malignancies, including monkeypox (Mpox), poses a…
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The Effect of Dampit Robusta Coffee Consumption and Submaximal Exercise on Myostatin Levels and Muscle Preservation in Adult Men: A Pilot Randomized Controlled Trial
Introduction: Myostatin has been linked to the pathogenesis of age-related muscle loss. Aerobic exercise and coffee polyphenols may modulate myostatin, but their combined effect in humans is unknown. To evaluate whether 5 days of Dampit robusta coffee consumption plus a single session of submaximal…
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Antileukemic Activity of Clitoria ternatea Extract and its Apoptotic Mechanism on Kasumi-1 Acute Myeloid Leukemia Cells
Introduction: Clitoria ternatea (commonly known as bunga telang) is considered a medicinal herb. It contains high levels of polyphenols, including anthocyanins and triterpenoids, and has demonstrated anticancer properties against various types of cancer cells. Nevertheless, the effects of this…
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Artikel Jurnal
Mapping Adolescent Nutritional Health: Early Clues for Preventing Obesity and Diabetes
Introduction: Adolescent obesity is rapidly increasing worldwide and is closely linked to early metabolic changes, including type 2 diabetes, highlighting the need for early identification using simple measures, i.e. body mass index (BMI), mid-upper arm circumference (MUAC), waist-to-height ratio…
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24-Hour Hypoalbuminemia as a Predictor of Sepsis in Severe Burns
Introduction: Burn injuries are associated with considerable morbidity and mortality, particularly when complicated by conditions such as sepsis. Hypoalbuminemia, frequently observed in burn patients, is hypothesized to elevate the risk of sepsis through mechanisms related to systemic inflammatory…
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Artikel Jurnal
Right Ventricular Dimension is a Predictor of Inhospital Mortality after Surgery in Late Presenting Mitral Valve Disease
Introduction: Mitral valve disease remains a major global heart-related issue affecting developed and developing countries. This study aimed to report overall mortality and evaluate perioperative factors contributing to postoperative inhospital mortality after isolated mitral valve replacement…
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Prevalence and Incidence Antimicrobial Resistance of Patients Pneumonia in Indonesia: Systematic Review and Meta-analysis
Introduction: Antimicrobial resistance (AMR) remains a threat in Indonesia. In this regard, AMR also poses a challenge in the management of pneumonia. This systematic review and meta-analysis aimed to evaluate the prevalence and AMR of pneumonia-causing microorganisms in Indonesia, with a focus on…
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Artikel Jurnal
Postresection Antiviral Treatment in Hepatocellular Carcinoma Patient with Undetected Hepatitis B virus DNA
Hepatocellular carcinoma (HCC) is a lethal cancer, and resection therapy is the main curative treatment. Nonetheless, the recurrence rate is the main obstacle, and postresection antiviral therapy use in those with low-level HBV DNA is still a dilemma. We report the case of a 62-year-old male with…
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Artikel Jurnal
Early Hyperglycemia is Associated with Sepsis in Pediatric Burn Patients: A 4-year Study in the Largest Burn Unit in Eastern Indonesia
Introduction: Pediatric burn injuries are associated with high morbidity and mortality, with sepsis being a major complication due to immature immune responses. Early physiological disturbances such as hypoalbuminemia and hyperglycemia are common in extensive burns and may contribute to increased…
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Artikel Jurnal
L-glutamine Supplementation Enhances Sperm Motility and Viability in Low-count Samples during Cryopreservation: Evidence from a Nonrandomized In vitro Study
Introduction: Sperm cryopreservation is a cornerstone of assisted reproductive technologies, yet the process often induces reactive oxygen species (ROS) formation, which compromises plasma membrane integrity and subsequently reduces motility and viability. L-glutamine has emerged as a promising in…