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NIHR Open Research
Scopus
ISSN 2633-4402 · F1000 Research Ltd · 255 articles in the index
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Journal Article
Introduction of confidential enquiry into maternal deaths in Ethiopia: Implementation and methodological considerations [version 1; peer review: 2 approved]
Background Despite having high maternal mortality, no recent confidential enquiry into maternal deaths (CEMD) has been implemented in Ethiopia. This paper outlines the introduction of the CEMD, major findings, and key methodological considerations. Methods We embedded this CEMD in the ongoing…
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Journal Article
Vulnerability and childhood immunization in Kenya. A systematic review of policy documents protocol. [version 3; peer review: 1 approved, 2 approved with reservations]
Abstract Introduction: Whereas improved full immunization coverage for childhood vaccines have been witnessed globally in the past decades, countries in sub-Saharan Africa have registered slow progress, with variations between and within countries. This has been attributed to several factors…
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Journal Article
Examining concepts related to critical illness and the management of critically ill patients: a protocol for a scoping review [version 1; peer review: 1 approved, 2 approved with reservations]
Background Critically ill patients present with highly complex care needs that necessitate specialised, efficient collaboration across multidisciplinary teams. Effective communication and shared understanding of clinical concepts are imperative to delivering optimised care and enhancing patient…
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Journal Article
Empirical oral AntibioticS for possible UTI in well appearing Young febrile infants (EASY) [version 2; peer review: 2 approved]
Background Urinary tract infections (UTIs) are the most common serious bacterial infections in febrile infants. Current UK guidelines recommend parenteral antibiotics for infants under three months with suspected UTI, despite evidence supporting oral therapy in low-risk infants. Objectives To…
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Journal Article
Development of a Cystic Fibrosis Weight Management Programme: protocol for a co-design study [version 2; peer review: 2 approved, 1 approved with reservations]
Background Since the recent introduction of highly effective modulator therapies (HEMT), adults with cystic fibrosis (CF) have experienced significant health improvements. However, HEMTs can also lead to weight gain, and over 30% of adults living with CF, are now overweight or obese. The English…
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Journal Article
Development of a Cystic Fibrosis Weight Management Programme: protocol for a co-design study [version 1; peer review: 2 approved, 1 approved with reservations]
Background Since the recent introduction of highly effective modulator therapies (HEMT), adults with cystic fibrosis (CF) have experienced significant health improvements. However, HEMTs can also lead to weight gain, and over 30% of adults living with CF, are now overweight or obese. The English…
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Journal Article
The pathway to diagnosis and follow-up care for atrial fibrillation in Sri Lanka: a descriptive longitudinal study [version 3; peer review: 1 approved, 2 approved with reservations]
Background Early diagnosis and continuity of care is vital for atrial fibrillation (AF), to reduce stroke ; There is a lack of understanding of when and how AF is being diagnosed and managed the care pathway) in in low- and middle-income countries (LMICs). We aimed to identify the AF care pathway…
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Journal Article
Clinical and cost-effectiveness of individualised exercises and foot orthoses in the treatment of plantar heel pain: protocol for the TREADON randomised multi-arm multi-stage adaptive trial [version 2; peer review: 2 approved, 2 approved with reservations]
Background Plantar heel pain (PHP) is the most common soft tissue foot condition and impairs mobility, physical function, ability to work, and quality of life. Systematic reviews highlight a need for high-quality randomised controlled trials (RCTs) of exercises and orthoses for PHP. Objectives To…
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Journal Article
Experiences of women from ethnic minorities and underserved, marginalised and disadvantaged groups in communicating with health professionals during antenatal care: An overview of qualitative systematic reviews [version 1; peer review: 1 approved, 2 approved with reservations]
Background Maternal mortality rates show disproportional disparities among disadvantaged groups. Objective To conduct an overview of qualitative systematic reviews to summarise the antenatal care experience of ethnic minority and underserved, marginalised and disadvantaged women in high-income…
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Journal Article
How to improve uptake and adherence to dietary trials in gestational diabetes amongst South Asian women: insights from patient and public involvement and engagement [version 3; peer review: 2 approved]
Background Gestational diabetes mellitus (GDM) is associated with adverse maternal and neonatal outcomes and affects approximately 10–20% of pregnancies in the UK. The prevalence of GDM among South Asian women is around twice that of White British women, and they are also twice as likely to develop…
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Journal Article
Heavy Rainfall and Flooding Effects on Maternal Health Service Delivery During Pregnancy and Childbirth in LMICs: A scoping review protocol. [version 1; peer review: 2 approved]
Introduction Climate change is a major global health challenge of the 21st century associated with the increasing frequency and severity of extreme weather events, including heavy rainfall and flooding. These extreme weather events are particularly disruptive in low- and middle-income countries…
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Journal Article
What are we missing? Reflections on the ‘problem’ of missed appointments in the UK [version 2; peer review: 1 approved, 2 approved with reservations]
Background Tackling missed appointments has become a prominent part of conversations about the ‘recovery’ of the UK NHS from the COVID-19 pandemic. With long waiting lists, delays in access to primary care, and overburdened staff, it seems logical that efforts should be made to reduce the time lost…
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Journal Article
Health economic studies of antimicrobial stewardship programmes: A scoping review [version 2; peer review: 3 approved]
Aims To conduct a scoping review of health economic evaluations of antimicrobial stewardship programmes (ASP). Our purpose was to summarise findings and to review different approaches taken. Methods We reviewed economic evaluation studies retrieved from a number of sources, assessing the costs and…
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Journal Article
Enabling scale and spread of technology-enabled remote monitoring of blood pressure at home: findings from a rapid qualitative evaluation [version 2; peer review: 2 approved, 1 approved with reservations]
Background High blood pressure (BP) is a leading cause of morbidity and mortality. Blood pressure home monitoring improves blood pressure control, but there is limited evidence about the implementation of specifically ‘technology-enabled’ remote monitoring of blood pressure (TERM BP) at home. This…
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Journal Article
Social and Ethical Aspects of Remote and Hybrid Care in the Special Allocation Scheme in general practice (SEARCH): A mixed methods feasibility study protocol [version 2; peer review: 1 approved, 2 approved with reservations]
Background Despite the growing body of research on remote primary care and access for (digitally) excluded groups, very little is known about care for patients who have been deliberately excluded from mainstream services. The ‘Special Allocation Scheme’ (SAS) in England provides GP services to…
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Journal Article
Developing community-based programme theories to address unmet needs of people experiencing homelessness and severe mental illness: protocol for a realist review [version 2; peer review: 2 approved]
Introduction People experiencing both homelessness and severe mental illness have complex needs requiring coordinated multi-sectoral and multilevel interventions. Several systematic reviews of interventions exist internationally; however, evidence on the mechanism of change and contextual factors…
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Journal Article
Engaging stakeholders in embedded newborn health services/systems research in Kenya : continuous process involving multiple actors [version 3; peer review: 2 approved, 1 approved with reservations]
Background Engaging relevant stakeholders throughout the research cycle is increasingly recognised as critical to conducting quality health systems research. There are few descriptions and analyses of stakeholder engagement in practice for embedded health systems research, especially those that…
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Journal Article
Travel behaviour and Edinburgh’s Low Emission Zone: a cross-sectional survey [version 2; peer review: 2 approved]
Background Low Emission Zones (LEZs) aim to improve air quality and encourage sustainable travel in urban areas by issuing fines to non-compliant vehicles. This study investigated initial impacts on travel behaviour and perceptions following the enforcement of Edinburgh's LEZ from June 2024…
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Journal Article
Can the diagnostic accuracy of newborn eye screening for congenital cataract be improved with digital imaging? The Digital Imaging versus Ophthalmoscopy (DIvO) study [version 2; peer review: 1 approved, 2 approved with reservations]
Abstract Background Congenital cataract is the commonest cause of preventable child blindness in the world. It affects 1: 3000 babies, 60% of whom will have bilateral disease. Although screening of the newborn red-reflex with an ophthalmoscope is recommended, there are questions over this…
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Journal Article
Experiences of women from ethnic minorities and underserved, marginalised and disadvantaged groups in communicating with health professionals during antenatal care: An overview of qualitative systematic reviews [version 2; peer review: 1 approved, 2 approved with reservations]
Background Maternal mortality rates show disproportional disparities among disadvantaged groups. Objective To conduct an overview of qualitative systematic reviews to summarise the antenatal care experience of ethnic minority and underserved, marginalised and disadvantaged women in high-income…