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Kidney360
Scopus
ISSN 2641-7650 · Wolters Kluwer - Lippincott Williams & Wilkins · 91 artikel di indeks
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Artikel Jurnal
Quantifying Time to Diagnosis of CKD in the United States
Key Points. Many people with CKD are unaware of the condition. We estimated the time to CKD documentation after two eGFR measurements taken at least 90 days apart. Among many persons with early stage CKD, there are considerable delays in documenting the diagnosis in electronic health record-linked…
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Artikel Jurnal
Optimizing Proteinuria Evaluation and Management after Acute Kidney Injury
Key Points. Quantifying albuminuria 3 months after AKI predicts future risk of kidney disease progression but is often not completed. In a cohort of 554 patients with CKD, urine protein-to-creatinine ratio measured within 1 year after AKI had robust prognostic value. Testing of total proteinuria…
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Artikel Jurnal
Artificial Intelligence in Critical Care Nephrology
Artificial intelligence (AI), including machine learning, deep learning, reinforcement learning, and generative AI, has the potential to advance critical care nephrology (CCN) by enhancing prediction accuracy, improving diagnostic capabilities, supporting clinical decision making, and streamlining…
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Artikel Jurnal
Association between Urinary Fractional Excretion of Potassium and Proteinuria Remission in Adult Nephrotic Syndrome
Key Points. Elevated fractional excretion of potassium (FEK) at biopsy predicts a lower rate of proteinuria remission in adults with nephrotic syndrome. FEK levels vary by histologic types, being low in minimal change disease and high in diabetic kidney disease, suggesting diagnostic utility. FEK…
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Artikel Jurnal
Novel Molecular Signatures of Peripheral Regulatory T Cells in Kidney Disease Associated with Type 1 Diabetes
Key Points. Regulatory T cells (Tregs) from people (control, type 1 diabetes with and without albuminuria) were profiled for phenotypic and transcriptomic changes. Central memory Tregs were reduced, while Treg EMRA+ cells were higher in type 1 diabetes with albuminuria. In silico findings suggest…
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Artikel Jurnal
Impact of Left Ventricular Geometry on All-Cause Mortality in Patients Undergoing Hemodialysis
Key Points. We evaluated the association between the four categories of left ventricular geometry and all-cause mortality in patients undergoing hemodialysis. Concentric hypertrophy was the most prevalent, followed by concentric remodeling, and these were associated with a high risk of mortality…
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Artikel Jurnal
Assessing Functional Cognition in People on Maintenance Hemodialysis Using Performance-Based Testing
Key Points. Approximately half of people on maintenance hemodialysis exhibited impairment on a standardized, performance-based assessment of functional cognition. The functional cognitive test correlated strongly with a traditional cognitive screening tool but weakly with self-report functional…
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Artikel Jurnal
NAD+-Boosting Ameliorates Heme Protein–Mediated Acute Kidney Injury
Key Points. Understanding how heme proteins/heme induce AKI and whether NAD+-boosting ameliorates heme protein–mediated AKI is clinically relevant. Heme proteins/heme directly decrease kidney NAD+ content and NAD+-boosting is markedly protective in heme protein–mediated AKI. These findings provide…
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Artikel Jurnal
Dapagliflozin Mitigates Medullary Hypoxia in CKD Patients
Key Points. Dapagliflozin significantly improves renal medullary oxygenation in CKD, constituting a potential mechanism of its nephroprotection. The enhancement of medullary oxygenation is more pronounced in nondiabetic patients, suggesting a distinct pathophysiologic response. Blood oxygenation…
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Real-World Patient Characteristics, Burden, and Quality of Life in C3 Glomerulopathy and Primary Immune Complex Membranoproliferative GN
Key Points. C3 glomerulopathy and primary immune complex-mediated membranoproliferative GN lead to a significant clinical, economic, and health care burden among affected patients and their families. C3 glomerulopathy and primary immune complex-mediated membranoproliferative GN drive high costs for…
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Artikel Jurnal
The Association of Kidney Function on Survival in Patients with Amyloid Light Chain Amyloidosis after Autologous Stem Cell Transplantation
Key Points. Almyloid light chain amyloid patients post autologous stem cell transplantation with higher eGFR was not associated with better progression-free survival but was associated with increased overall survival (OS). Patients with kidney amyloidosis stage 3 at baseline had inferior OS…