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BMC Chemistry
Scopus
ISSN 2661-801X · BMC · 1.342 artikel di indeks
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Artikel Jurnal
Antioxidant dipeptide Threonyltyrosine from Porphyridium cruentum: in silico prediction and in vitro protection against paraquat-induced HaCaT cell damage
Abstract Marine microalgae rich in high-quality proteins are highly favored in the development of bioactive peptides. However, the scarcity of effective preparation methods still limits its application in healthy improvement. This study aimed to search for the effective natural antioxidative…
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Artikel Jurnal
Synthesis, X-ray, molecular electronic property investigation, and molecular docking analysis of two imino Schiff bases
Abstract In this study, we report the first synthesis and comprehensive characterization of two positional isomers of iodo-substituted imino Schiff bases, Im1 was synthesized using 2-iodoaniline, whereas Im2 was obtained from 4-iodoaniline. Compound Im1 represents a new derivative, while Im2 is…
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Artikel Jurnal
Development of a biosensor for spectrophotometric determination of l-lactate in artificial saliva
Abstract Analysis of critical biomarkers like l-lactate is extremely important in clinical practice. Herein, a non-invasive and sensitive colorimetric biosensor for accurate l-lactate determination has been developed. The proposed method demonstrates the ability of Fe3+ ions of iron(III) chloride…
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Artikel Jurnal
Purification of aqueous fluids from basic fuchsine employing a new polymer of CMC-CMS hydrogel mixture: sustainability perspective
Abstract Medical laboratory waste, generated during diagnostic and research activities, contains pathogenic microbes and carcinogenic chemicals that pose significant risks to environmental and human health. To address this issue, physicochemical treatment methods such as hydrogel-based adsorption…
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Artikel Jurnal
Novel pyrazole-clubbed triazole scaffolds as promising inhibitors for carbon steel corrosion in sulfuric acid and as antibacterial agents: electrochemical and computational evaluation
Abstract Herein, two novel pyrazole-clubbed triazole scaffolds were synthesized, characterized, and evaluated as inhibitors for carbon steel dissolution in 0.5 M H2SO4 via open circuit potential (OCP), potentiodynamic polarization (PP), electrochemical impedance spectroscopy (EIS), potential of…
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Artikel Jurnal
Silver nanoparticles-based green fluorescent probe for determination of Bosentan in pharmaceutical formulation and spiked plasma samples
Abstract In this work, a new, sensitive, precise, accurate, and eco-friendly spectrofluorometric method for the detection of Bosentan in human plasma and pharmaceutical dosage form was developed, using silver nanoparticles (AgNPs) as an efficient fluorescence sensing probe. The general concept used…
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Artikel Jurnal
A dual-detection HPTLC platform: combining smartphone-based imaging and densitometry for the analysis of diazepam, its metabolite and degradation product
Abstract In recent years, high-performance thin-layer chromatography (HPTLC) has gained prominence as a cost-effective, straightforward, and dependable analytical technique, particularly in forensic and pharmaceutical laboratories. With the rapid evolution of smartphone technologies, a novel…
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Artikel Jurnal
The first validated HPLC method with UV detection for concurrent assay of lidocaine and fluorescein in their co-formulated ophthalmic solution
Abstract A simple, fast, and eco-friendly high-performance liquid chromatography (RP-HPLC) method has been developed for the concurrent quantification of lidocaine and fluorescein, employing ultraviolet detection at a wavelength of 220 nm. The chromatographic separation was applied under isocratic…
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Artikel Jurnal
A newly developed covalent organic framework decorated with chromium for efficient methanol fuel cell
Abstract Covalent Organic Frameworks (COFs) have emerged as a promising class of crystalline porous materials with potential applications in various fields, including catalysis, gas storage, and energy conversion. A novel COF was prepared from the reaction of terephthalaldehyde and…
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Artikel Jurnal
Green RP-HPLC method for estimation of trigonelline: AQbD based development, validation, and application to nanoformulations
Abstract Trigonelline is an alkaloidal plant derived bioactive compound reported for its various pharmacological activities. Recent advances in the utilization of this compound in drug development have highlighted the importance of establishing a reproducible and efficient analytical method for…
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Artikel Jurnal
Novel and sustainable microfabricated Cu ion selective sensor doped with ionophore and supported with docking study for determination of vonoprazan fumarate in tablet dosage form
Abstract In the field of drug analysis, there is a growing emphasis on developing techniques that are environmentally friendly, cost-effective, and efficient. To align with the principles of green analytical chemistry and to support the advancement of portable and handheld devices, an innovative…
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Artikel Jurnal
Coordination versatility and enhanced bioactivity of Co2+, Cu2+ and Cd2+ complexes derived from pyridyl Schiff base: structural, electronic and electrochemical insights
Abstract A Schiff base ligand, H2L, was obtained from the condensation of pyridine-2,6-dicarbohydrazide and cinnamaldehyde and was further complexed with Co2+, Cu2+, and Cd2+ ions. The coordination complexes were then analyzed by normal spectroscopic/microscopic analyses (FT-IR, UV–visible, 1H-NMR…
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Artikel Jurnal
Acemetacin-loaded bilosomal gel formulations prepared using different polymers for topical application: Box-Behnken design for bilosomes formulation optimization and in vitro evaluation of the formulations
Abstract Acemetacin (ACIN) is a poorly water-soluble nonsteroidal anti-inflammatory drug, which limits its effectiveness in topical therapeutic applications. This study aimed to enhance the delivery potential and dermal applicability of ACIN through the development of bilosome-loaded hydrogel…
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Artikel Jurnal
Environmentally sustainable UV spectrophotometric–chemometric approach for simultaneous determination of budesonide, glycopyrrolate, and formoterol
Abstract This study introduces a sustainable UV-spectrophotometric platform for the simultaneous and individual determination of budesonide (BUD), glycopyrrolate (GLY), and formoterol fumarate (FOM) in pharmaceutical inhalers. Current chromatographic approaches for this triple therapy rely on toxic…
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Artikel Jurnal
Green evaluation of human plasma levels of metformin, linagliptin, and empagliflozin using HPLC and HPTLC methods: a pharmacokinetic study
Abstract Two simple, rapid, cost-effective, and environmentally friendly chromatographic methods were developed and validated for the simultaneous determination of metformin (MEF), linagliptin (LIN), and empagliflozin (EMP) in human plasma, with successful application to pharmacokinetic study…
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Artikel Jurnal
Study on the treatment of methyl orange contaminated water by activated carbon fiber/copper oxide as persulfate activator under microwave irradiation
Abstract To effectively treat refractory azo dye wastewater, microwave advanced catalytic oxidation technology was adopted to degrade the model pollutant methyl orange using activated carbon fiber (ACF)/CuO as the catalyst and potassium persulfate (K2S2O8) as the oxidant. The optimized experimental…
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Artikel Jurnal
Highly fluorescent method for ultra-sensitive estimation of delafloxacin in human plasma: greenness assessment
Abstract A simple, rapid, sensitive, and reliable spectrofluorimetric approach has been developed for the analysis of delafloxacin (DEL) in human plasma. The proposed method is based on the formation of a micellar fluorescent complex through the interaction of DEL with 2% sodium dodecyl sulfate…
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Artikel Jurnal
Normalized vs factorized spectra: comparative spectrophotometric approaches for enhancing the resolution of zero-order absorption spectra of olanzapine and fluoxetine in mixtures
Abstract Simple, accurate, and precise UV spectrophotometric methods were developed and validated for the simultaneous determination of olanzapine (OLA) and fluoxetine (FLU) in bulk powders and combined pharmaceutical formulations without prior separation steps. The methods employed advanced…
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Artikel Jurnal
Design, synthesis, and evaluation of novel triazole-based carbohydrazide derivatives with notable antioxidant activity: an integrated experimental and DFT study
Abstract A series of novel heterocyclic compounds based on 5-methyl-1-(p-tolyl)-1H-1,2,3-triazole-4-carbohydrazide were designed, synthesized, and evaluated for antioxidant activity. The synthesized derivatives included phthalimide (NA-1, NA-2), cyanoacetamide (NA-3), pyridine-based (NA-4), and…
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Artikel Jurnal
Synthesis, structural characterization, DFT calculation, and antitumor activity of a new Co(II) complex based on 2-((2′-Carboxybenzyl)oxy)benzoic acid and 2,2′-bipyridine ligands
Abstract In this work, a new Co(II) complex, abbreviated as [Co(L)(bipy)(H2O)2] n (1) was prepared using cobalt(II) acetate tetrahydrate, 2-((2’-carboxybenzyl)oxy)benzoic acid (H2L), and 2,2’-bipyridine (bipy) ligands in a mixture solution of ethanol and water (v: v = 3: 1). The structure of the…
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