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Медична наука України
ISSN 2664-472X · Bogomolets National Medical University · 500 artikel di indeks
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Artikel Jurnal
Tear fluid levels of interleukin-6 and tight junction protein ZO-1 and their association with the course of bacterial keratitis in type 2 diabetes mellitus under martial law in Ukraine
Relevance. Bacterial keratitis is one of the most common infectious diseases of the cornea and may lead to severe complications, persistent visual impairment, and disability. Aim. To investigate the levels of interleukin-6 and the tight junction protein zonula occludens-1 in the tear fluid of…
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Artikel Jurnal
Determination of predictors of non-carious cervical lesions of teeth using logistic regression analysis
Relevance. Non-carious cervical lesions of teeth remain the second reason for contacting the dentist after tooth decay and its complications. Aim. To determine predictors of the occurrence and progression of wedge-shaped defect (WSD) and erosion (E) of tooth enamel in young patients. Materials and…
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Artikel Jurnal
Features of physical therapy for lumbar hernias in military personnel during the late stage of rehabilitation
Relevance. This study addresses the issue of rehabilitation for military personnel with lumbar disc herniation, which poses a critical challenge due to high levels of physical exertion and combat stress. Aim. To investigate the effectiveness of manual therapy as a means of correcting the…
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Artikel Jurnal
Dynamic renal scintigraphy with 99mTc-DTPA in the differential diagnosis of acute tubular necrosis and acute renal allograft rejection in the early post-transplant period
Relevance. Worldwide, people recognise kidney transplantation as the standard treatment for end-stage kidney failure. However, impaired graft function frequently complicates the early postoperative period. The most common causes of early dysfunction are acute tubular necrosis and acute rejection…
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Artikel Jurnal
Systemic biomarkers of apoptosis and endothelial activation in the pathogenesis of rubeosis iridis and iridocorneal angle neovascularisation in secondary neovascular glaucoma
Aim. To assess systemic levels of CD95 (Fas) and ICAM-1 (CD54) in patients with secondary neovascular glaucoma (NVG), to determine the relationship with the severity of iris rubeosis and the iridocorneal angle, and to evaluate the role of endothelial apoptosis in neovascular remodelling of the…
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Artikel Jurnal
Routine screening for scoliosis in children at primary care level and its significance in the prevention and timely diagnosis of complications
Relevance. Scoliosis in children is a common orthopaedic condition that may be accompanied by progressive spinal deformity, impaired function of internal organs and a reduced quality of life. Early detection of postural abnormalities at the primary care level is crucial for timely treatment and the…
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Artikel Jurnal
System for forming and maintaining the competence of rapid response teams of the Centres for Disease Control and Prevention of the Ministry of Health of Ukraine
Relevance. Under modern biological, chemical, radiological, and other threats to public health, improvement of the system for developing and maintaining the competence of rapid response teams of the Centres for Disease Control and Prevention becomes particularly important. Aim. To identify the main…
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Artikel Jurnal
Comparative effectiveness of robot-assisted and laparoscopic procedures in deep infiltrating endometriosis
Relevance. The importance of the study is determined by the high prevalence of endometriosis among women of reproductive age and by the substantial negative effect of deep infiltrating endometriosis on the functional state of the pelvic organs, the quality of life of patients, and treatment…
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Artikel Jurnal
Substantiation of medical and sanitary standards for permissible levels of carcinogenic substances in ambient air in populated areas, taking into account the experience of EU countries
Relevance. Ukraine’s integration into the European Union requires the harmonisation of national legislation with European standards. One of the priority areas is the improvement of the system of medical and sanitary standards for hazardous substances in ambient air. Unlike the EU Member States and…
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Artikel Jurnal
The association between patients’ sociodemographic characteristics and out-of-pocket payments during chemotherapy for colorectal cancer
Relevance. Colorectal cancer (CRC) is one of the three most prevalent malignancies in terms of incidence and mortality, both in Ukraine and worldwide. Despite Ukraine’s healthcare financing reform, out-of-pocket payments by patients remain a significant concern. Aim. To compare the sociodemographic…
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Artikel Jurnal
Dynamics of antimicrobial consumption in an inpatient surgical department following the implementation of an antimicrobial stewardship programme
Relevance. Antimicrobial stewardship (AMS) programmes have become an important strategy for optimising antibiotic use and combating antimicrobial resistance in surgical practice. Aim. To evaluate the impact of implementing an AMS on antibiotic consumption in an inpatient surgical department…
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Artikel Jurnal
Home-based cardiac rehabilitation after myocardial infarction in the long-term rehabilitation period: Evidence base and prospects for development
Relevance. Myocardial infarction is accompanied by long-term functional, clinical, and psycho-emotional consequences, whereas insufficient accessibility of traditional centre-based cardiac rehabilitation programmes determines the need for evidence-based home-based, hybrid, and telerehabilitation…
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Artikel Jurnal
Features of the course of pregnancy and labour and the condition of newborns in women after in vitro fertilisation
Background. Infertility remains a significant issue in reproductive medicine, and pregnancy following IVF requires specialised medical supervision due to differences in its course compared with physiological pregnancy. Aim. To determine the characteristics of pregnancy, labour, and neonatal…
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Artikel Jurnal
Clinical features and diagnostic errors in the manifestations of pemphigus vulgaris in the oral cavity
Relevance. Pemphigus vulgaris is a rare autoimmune bullous disease characterised by the formation of intraepithelial blisters and erosions. Often, the oral mucous membrane is the first and, for quite some time, the only area affected by this disease. The oral manifestation of the disease is often…
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Artikel Jurnal
A review of the therapeutic and neuroprotective properties of ketamine
Relevance. Depression is one of the leading causes of disability worldwide, and a significant proportion of patients suffer from treatment-resistant forms of the disorder. An innovative approach involves the use of ketamine and esketamine, which are capable of inducing a “window of neuroplasticity”…
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Artikel Jurnal
Adverse course of COVID-19 despite the use of molnupiravir: A clinical case
Relevance. Patients with type 2 diabetes mellitus are at high risk of severe COVID-19, multiple organ failure, and death. Despite the introduction of direct-acting antiviral agents, including molnupiravir, some patients may still experience an unfavourable outcome despite early initiation of…
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Artikel Jurnal
Psychoneuroimmunological mechanisms of stress-induced mental and psychosomatic disorders
Relevance. Psychosomatic disorders represent a significant medical and biological problem, as their development is linked to the chronic activation of stress-mediating systems, in particular the hypothalamic-pituitary-adrenal axis and immuno-inflammatory mechanisms, which contribute to the…
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Artikel Jurnal
Morphological features of renal glomerular injury in experimental diabetes mellitus and their correction through the inhibition of cellular protein kinases
Relevance. Diabetic nephropathy significantly impairs patients’ quality of life, leads to loss of working capacity, and is associated with high mortality. Current scientific trends demonstrate a transition from a conventional approach focused solely on normalising blood glucose levels towards…
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Artikel Jurnal
Implementation of assistive technologies for rehabilitation of children with hearing impairments
Relevance. Hearing impairments in children negatively affect speech development, cognitive functions, learning and social adaptation, whereas the use of assistive technologies helps compensate for sensory deficits, improve speech perception and promote the child’s more effective integration into…
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Artikel Jurnal
Expression of PMS2 and p53 proteins in retinal tissues in experimental diabetic retinopathy and the effects of insulin and cellular protein kinase inhibition
Relevance. The relevance of the study lies in the need to clarify the role of DNA repair mechanisms and genomic stress in the pathogenesis of diabetic retinopathy for the search for new therapeutic targets. Aim. To determine the expression of PMS2 and p53 proteins in the retinal tissues of rats…