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Current Research in Physiology
Scopus
ISSN 2665-9441 · Elsevier · 172 artikel di indeks
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Artikel Jurnal
Sex differences in brachial and superficial femoral artery occlusion pressure
It is well accepted that arterial occlusion pressure (AOP) of the arm and leg should be measured prior to blood flow restriction (BFR) training. Although limb circumference is a key determinant of AOP, there is mounting evidence suggestive of sex differences in AOP. Objective: To further clarify…
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External mechanical efficiency across incremental VO2 max stages and ventilatory efficiency in well-trained and less-trained adults
Background/objective: External mechanical efficiency (EME%) and ventilatory efficiency (VEF) reflect endurance performance, yet comparisons between well-trained (WT) and less-trained (LT) runners during incremental exercise are limited. This study examined stage-specific changes in EME% and VEF…
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Progression of early diagnostic markers for diabetic kidney disease: From single-indicator detection to multi-omics integration modeling
Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease (ESRD), but early diagnosis remains challenging. Current reliance on indicators such as urinary albumin and glomerular filtration rate is limited by insufficient sensitivity and susceptibility to interference. The…
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How effective is online teaching of physiology modules? perception of Rwandan health sciences students
Background: While blended teaching is approved in Rwandan medical education, the perceived effectiveness of online-only delivery for physiology modules remains unclear. This uncertainty limits its continued use. The present study assessed Rwandan health sciences students’ perceptions of the…
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Sex and dose differences in morphine administration on renal function, inflammatory and apoptotic markers in male and female Wistar rats
This study examined the impact of morphine on renal function, antioxidant enzymes, and inflammatory and apoptotic markers in male and female Wistar rats, considering both sex- and dose-dependent effects. 40 Wistar rats (20 male, 20 female), each weighing 120–150 g were used in this study. The…
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Vascular adaptation in elite female and male rowers across a competitive season
The ‘athlete's artery’ phenotype describes exercise-induced vascular adaptation whereby athletes have enlarged conduit arteries resulting from chronic endurance exercise. However, studies remain limited to males, with few evaluating changes in response to training. This study aimed to compare upper…
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Using digital escape rooms to enhance data analysis skills and student experience in a higher education human physiology module
Active and gamified teaching methods have garnered significant interest, with an increased demand for higher education institutions to enhance student engagement. One popular example of active learning is the escape room. Escape rooms are playful tools reported to increase students’ key…
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Effects of short-term sleep reduction and aerobic exercise on metabolism and inflammation in healthy adults
The purpose of this study was to explore the effects of short-term sleep reduction on metabolic variables at rest and during acute aerobic (AE) exercise in healthy adults. This study followed a within subjects, repeated measures design. Following resting measures, recreationally active adults (n =…
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Role of obesity in chronic kidney disease progression
Obesity is a global health epidemic linked to numerous chronic disease conditions and consequences, including type 2 diabetes mellitus (T2DM), cardiovascular disease, chronic kidney disease (CKD) and premature mortality. CKD, which can progress to end stage renal disease (ESRD) and/or dialysis with…
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The persistence of changes in insulin sensitivity and metabolic gene expression after acute exercise in male and female mice
Background: Acute exercise has been suggested to increase insulin sensitivity, although the duration of the improvement may last anywhere from 4 to 72 h. In addition, changes in gene expression in response to exercise is suggested to last at least 24 h. Despite this, exercise training studies…
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Carnosine ameliorates dexamethasone-induced muscle atrophy with associated modulation of ubiquitin ligases and oxidative stress in C57BL/6J female mice
Muscle atrophy, characterized by a decline in muscle mass and function, has limited treatment options, highlighting the need for further research. In this study, we investigated the effect of carnosine, a dipeptide with well-established antioxidant properties, on dexamethasone (Dex)-induced muscle…
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Serum electrolytes and blood urea nitrogen changes in end-stage renal disease patients undergoing contemporary haemodialysis: A multi-center cross-sectional study
Background: Correction of electrolyte imbalance and adequate haemodialysis (HD) minimizes disease complications and hospitalization. Despite the problem, there is a paucity of data regarding the assessment of serum electrolytes and blood urea nitrogen changes (BUN) in end-stage renal disease…
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The senescent synapse: A look at autophagy, calcium handling, and mitochondrial bioenergetics at the synapse in ageing and Parkinson's disease
The synapse is a vitally important physiological structure fundamental to electrochemical communication between neurones, and is required for basic and important functions we perform daily. Underpinning the normal physiological function of the synapse are crucial processes such as autophagy…
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The beneficial effect of propolis during an eight-weeks of resistance training on TNF-α and IL-6 genes expression in the kidney tissue of female Wistar rats undergoing testosterone enanthate consumption
This study investigated the potential benefits of propolis in mitigating the adverse effects of testosterone enanthate on the gene expression levels of pro-inflammatory cytokines, tumor necrosis factor-alpha (TNF-α), and interleukin-6 (IL-6) in the kidney tissue of female Wistar rats undergoing…
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Differential responses to acute endurance exercise-induced signaling protein phosphorylation and abundance alterations in whole murine gastrocnemius muscle and isolated myofibers
Skeletal muscle is composed of diverse cell types, including myofibers. In this study, we investigated how acute endurance exercise could induce signaling protein phosphorylation and abundance alterations using protein lysate extracted from whole-muscle tissue or isolated myofibers. We subjected…
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Exploration of neural mechanisms underlying antidepressant-like property of Ziziphora clinopodioides Lam. essential oil using mouse forced swimming test: Involvement of the monoaminergic systems
Objective: Ziziphora clinopodioides has been valued in Iranian traditional medicine for various medicinal applications. This novel study was conducted to assess the antidepressant-like effect of the essential oil of Ziziphora clinopodioides (EOZC) and to identify the possible mechanisms…
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Sex-related differences in the acute physiological response to a high-intensity CrossFit® workout
CrossFit® is popular form of fitness training but the cardiorespiratory, hemodynamic and metabolic responses have not been well characterised. We compared responses to a short Fran CrossFit® session (consisting of three rounds of 21, 15 and 9 front squat to press overhead and pull-ups) between…
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Sex differences in the association between albuminuria and vascular health in individuals living with chronic kidney disease
Cardiovascular disease is the leading cause of death in chronic kidney disease (CKD). Albuminuria, a marker of CKD severity, is independently associated with cardiovascular disease, however limited studies explore the impact of sex. We aimed to explore sex differences in the association between…