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Human Nutrition & Metabolism
Scopus
ISSN 2666-1497 · Elsevier · 251 artikel di indeks
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Artikel Jurnal
Universal salt iodization remains insufficient to prevent iodine deficiency without maternal education and improved household salt practices: insights from structural equation modelling in Noakhali
Background: Despite decades of universal salt iodization (USI), iodine deficiency remains a persistent public health problem in Bangladesh, mainly impacting children in rural and socioeconomically disadvantaged communities. Methods: A cross-sectional survey of 400 children (6–12 years) in four…
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Artikel Jurnal
Serum 25(OH)D levels are causally linked to height in European population: A mendelian randomization study
Purpose: To explore the causal relationship between serum vitamin D status and height, given that adequate vitamin D is essential for individuals to achieve their genetic height potential. Methods: A Mendelian randomization (MR) study was conducted. Instrumental variables (IVs) were derived from…
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The effects of a high-fiber diet on biomarkers used to assess intestinal inflammation and permeability in healthy individuals
Objectives: The present study was conducted with the objective of testing the hypothesis that a dietary intervention promoting a diet in which at least 30 g of total dietary fibre intake per day is obtained from foods affects markers related to intestinal integrity and inflammation in healthy…
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Artikel Jurnal
Influence of dietary interventions and nutrients on oestrogen dominance in males: A systematic review
Background: As males age, declining testosterone levels may result in a relative hormonal imbalance, often described as “estrogen dominance.” Up to 30 % of males aged ≥60 years experience low testosterone levels which can alter the testosterone-to-oestrogen ratio and contribute to associated…
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Artikel Jurnal
Causal relationship between folate and thrombotic external hemorrhoids: A two-sample Mendelian Randomization analysis
Background: Thrombotic external hemorrhoids (TEH) may be influenced by micronutrient levels. This study investigates the causal relationship between TEH and 15 micronutrients, including folate, calcium, and vitamins A, C, D, E, B6, and B12. Methods: A two-sample Mendelian randomization (MR)…
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Artikel Jurnal
Investigation and analysis of vitamin D status in a coastal city population of southeast China
Objectives: To characterize vitamin D levels and related influencing factors in the population of coastal cities in southeast China. Methods: We retrospectively analyzed the results of serum 25-hydroxyvitamin D3 [25(OH) D3] during outpatient visits and physical examinations at Ningbo Hangzhou Bay…
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Associations of SLC30A8 polymorphisms with metabolic and dietary parameters in a Brazilian obesity cohort
Background: Obesity is a complex condition influenced by genetic and environmental factors. Beyond known appetite/satiety single nucleotide polymorphisms (SNPs), comprehensive genomic screening can reveal novel and clinically relevant associations. Objective: To investigate genetic associations of…
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Dietary influences on the gut-brain pathways: Mechanisms and therapeutic potential
There is emerging evidence that the gut-brain axis can be significantly influenced through a gut friendly diet. Indeed, nutritional neuroscience holds a significant role in managing the gut brain axis and mental health disorders as numerous pathways, chiefly, neurological, humoral and immune…
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Artikel Jurnal
Association between dietary inflammatory index with metabolic syndrome and inflammation in middle-aged and older adults: A cross-sectional study
Background and aim: Dietary patterns play a significant role in the development of chronic metabolic diseases. The dietary inflammatory index (DII) is a tool utilized to evaluate the inflammatory potential of a diet. This study aimed to examine the association of DII with metabolic syndrome and…
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Dietary micronutrients and habitual dietary patterns are associated with infertility risk among individuals with high insulin resistance: A machine learning analysis of NHANES and MyPyramid Equivalents Database
Background: Insulin resistance is increasingly recognized as a key metabolic factor in reproductive dysfunction. However, the relationship between dietary factors and infertility risk among individuals with high insulin resistance remains insufficiently understood, especially from a data-driven…
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Artikel Jurnal
Effect of phytosomal berberine and monacolin K association on glyco-metabolic and lipid parameters in dysglycemic and hypercholesterolemic patients
Objective: To evaluate the effect of Berberol K® on glycemic and lipid parameters as well as glycemic status variation in dysglycemic and hypercholesterolemic patients. Materials and methods: This study was performed on 124 patients who received placebo or Berberol K®, 1 tablet per day, for 6…
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Artikel Jurnal
Artificial intelligence for precision obesity phenotyping and cardiometabolic risk stratification: A critical narrative review
Background: Body mass index is a widely used obesity metric but does not adequately capture adiposity distribution, metabolic dysfunction, or individual cardiometabolic risk, leading to misclassification of conditions such as normal-weight obesity, metabolically healthy obesity, and excess visceral…
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Theory of lipid metabolism disorder in rhinitis and asthma (hepato-lung axis)
We propose a theory regarding the role of lipid metabolism disorders in rhinitis and asthma. The liver is the most critical organ for lipid metabolism in the body, with bile acids playing the most significant role. Due to space limitations, this article focuses solely on an in-depth discussion and…
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Lifestyle and anthropometric determinants of eGFR based on cystatin C or creatinine serum concentrations in healthy, young males
Background: The estimated glomerular filtration rate (eGFR), derived from serum creatinine (eGFRcr) or cystatin C (eGFRcys), is crucial for assessing kidney function and predicting health outcomes. While eGFRcr is known to be influenced by muscle mass and diet, eGFRcys is considered unaffected…
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Artikel Jurnal
Association between iron intake and risk of all-cause mortality in patients with nonalcoholic fatty liver disease: a retrospective study of NHANES
Background: The objective of this study was to assess how dietary iron intake relates to the risk of all-cause mortality among individuals with non-alcoholic fatty liver disease (NAFLD). Methods: The research comprised a total of 9240 individuals diagnosed with NAFLD, obtained from the National…
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The interplay between gut microbiota metabolites and host body: Implications in health and disease
The gut microbiota has co-evolved with its host and forms an essential component of the human body. It is acquired at birth and continues to develop alongside the host, preserving its diversity and stability throughout life. The gut microbiota converts ingested foods into various metabolites…
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Gut microbiota alterations in adult individuals with obesity and insulin resistance: Its association with metabolic parameters and body compositions
An emerging body of evidence has highlighted the complex interplay among obesity, insulin resistance, and the gut microbiota. This observational study aimed to evaluate differences in intestinal microbiome profiles between individuals with obesity, with and without insulin resistance. Twenty…
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Effects of pomegranate on blood pressure and endothelial function: A systematic review and meta-analysis of clinical trials
This systematic review and meta-analysis evaluated pomegranate supplementation effects on blood pressure and endothelial function in adults. Four main databases, including PubMed/MEDLINE, Web of Science, SCOPUS, and Embase databases, were searched from inception to January 2026 to identify clinical…
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Artikel Jurnal
Impact of resistance, endurance, and combined exercise training on lipid profile, apolipoprotein A-1, and nitric oxide synthase expression in women with type 2 diabetes: A randomized controlled trial
Background: Type 2 diabetes mellitus (T2DM) involves metabolic disturbances and endothelial dysfunction, raising cardiovascular risk. Objective: To compare the effects of 8 weeks of resistance, endurance, and combined exercise on serum apolipoprotein A-1 (ApoA1), lipid profile, nitric oxide (NO)…