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European Urology Open Science
Scopus
ISSN 2666-1683 · Elsevier · 4.166 artikel di indeks
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Artikel Jurnal
Oncologic Outcomes in a Contemporary “PROTEUS-like” Cohort of High-risk Prostate Cancer Treated with Radical Prostatectomy Without Neoadjuvant Hormonal Therapy
Background and objective: High-risk prostate cancer (PCa) carries substantial risks of recurrence, metastasis, and mortality. Neoadjuvant therapy before radical prostatectomy (RP) remains investigational. The PROTEUS (NCT03767244) trial evaluates perioperative apalutamide + androgen deprivation…
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Artikel Jurnal
Prospective Evaluation of Blood-based and Microbiological Early Indicators of In-hospital Infectious Complications After Open Cystectomy
Background and objective: In-hospital infectious complications after cystectomy are understudied, with no reliable predictive tools. The aim of our study was to (1) comprehensively and prospectively evaluate these complications, (2) compare results between ileal conduit (IC) and ileal neobladder…
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Artikel Jurnal
Renal Function Outcomes in Tuberous Sclerosis Complex Patients Receiving Everolimus for Renal Angiomyolipoma
Background and objective: Everolimus has been proved effective in treating renal angiomyolipoma (RAML) associated with tuberous sclerosis complex (TSC). However, its impact on renal function remains uncertain. Methods: We analyzed changes in the estimated glomerular filtration rate (eGFR) in 54…
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Artikel Jurnal
Integrated Assessment of Percentage α2,3-Linked Sialylated Prostate-specific Antigen and the Prostate Health Index with Magnetic Resonance Imaging for Detection of Clinically Significant Prostate Cancer
Background and objective: The diagnostic roles of serum percentage α2,3-linked sialylated prostate-specific antigen (S2,3PSA%) and the Prostate Health Index (PHI) in predicting clinically significant prostate cancer (csPC) remain unclear in the context of magnetic resonance imaging (MRI)-guided…
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Artikel Jurnal
Penis “En Bloc”: From Reproducible Harvesting to Transplantation in a Cadaver study
Background and objective: Our aim was to assess the reproducibility of en bloc penile harvesting with a focus on the vascular structures to determine whether the procedure could be performed while preserving critical vascular supply. Methods: A single-center, prospective cadaver study was conducted…
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Artikel Jurnal
Downregulation of ANPEP Is Associated with Aggressive Prostate Cancer and Poor Disease-specific Outcomes
Background and objective: Aminopeptidase N (ANPEP) is linked to malignancy in certain tumor types, but its role in aggressive prostate cancer (PCa) is less well defined. Our aim was to characterize ANPEP expression in various PCa stages to determine whether it is a robust prognostic biomarker of…
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Artikel Jurnal
Robot-assisted Buccal Mucosa Graft Ureteroplasty for Ureteral Stricture: A European Multicenter Case Series
Background and objective: Robot-assisted buccal mucosa graft (BMG) ureteroplasty was introduced a decade ago and has since gained wide adoption within the urology community. However, available data on the outcomes of robot-assisted BMG ureteroplasty remain limited, and no large European series has…
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Artikel Jurnal
Decisional Regret and Long-term Quality of Life After Artificial Urinary Sphincter Implantation Following Radical Prostatectomy
Background and objective: Insertion of an artificial urinary sphincter (AUS) is the reference treatment for stress urinary incontinence (SUI) after radical prostatectomy (RP). Although long-term outcomes have been characterised, data on decisional regret remain limited. Our aim was to evaluate…
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Artikel Jurnal
Transperineal Versus Transrectal Prostate Biopsy: A Systematic Review and Meta-analysis of Randomized Controlled Trials Across Settings With and Without Magnetic Resonance Imaging Targeting
Background and objective: While transperineal prostate biopsy (TP-Bx) is increasingly being used to mitigate infection risk, its diagnostic equivalence to transrectal biopsy (TR-Bx) remains under investigation. Our aim was to comprehensively compare the diagnostic performance and complication…
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Artikel Jurnal
Association of Socioeconomic Position, Prostate-specific Antigen, and Age with Observation in Low-risk Prostate Cancer Patients in Switzerland
Background and objective: Observation remains the recommended management approach for low-risk prostate cancer (PCa), aiming to balance oncological control and avoidance of overtreatment. This study investigated the use of observation and its association with patients’ socioeconomic position (SEP)…
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Artikel Jurnal
Mapping of QLQ-C30 and QLQ-PR25 Scores to EQ-5D-5L Utility Values for Patients with Prostate Cancer Receiving Novel Androgen Receptor Signaling Inhibitors
Background and objective: Disease-specific questionnaires provide detailed health insights and are increasingly used in mapping studies to estimate utility values. Given the limited mapping studies in prostate cancer, our aim was to develop mapping algorithms to convert scores from disease-specific…
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Artikel Jurnal
Long-term Real-world Survival Outcomes with Dual Immune Checkpoint Blockade in Synchronous Metastatic Renal Cell Carcinoma: Implications for the Design of Prospective Cytoreductive Nephrectomy Trials
Background and objective: Patients with synchronous metastatic renal cell carcinoma (s-mRCC) increasingly undergo systemic therapy with their primary tumour in situ. We report long-term survival outcomes and deferred cytoreductive nephrectromy (dCN) rates in an unselected real-world s-mRCC cohort…
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Artikel Jurnal
Cost Comparison of Percutaneous Nephrolithotomy With and Without Intraoperative Cone-beam Computed Tomography: 18-month Postoperative Analysis
Background and objective: Residual fragments (RFs) after percutaneous nephrolithotomy (PCNL) increase the risk of stone-related events (SREs) such as reinterventions and emergency department (ED) visits. Intraoperative cone-beam computed tomography (CBCT) facilitates detection and removal of RFs to…
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Artikel Jurnal
Impact of Negative Prostate-specific Membrane Antigen Positron Emission Tomography on the Decision to Perform a Pelvic Lymph Node Dissection During Radical Prostatectomy for Intermediate- to High-risk Prostate Cancer Patients: Results of an International Survey
Background and objective: Pelvic lymph node dissection (PLND) is considered the most reliable method for managing prostate cancer (PCa). However, the role of PLND remains controversial in both clinical practice and guideline recommendations. This study aims to characterize contemporary practices…
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Artikel Jurnal
Long-term Survival of Midurethral Mesh Slings for Women with Stress Urinary Incontinence
Background and objective: Midurethral sling (MUS) use for stress urinary incontinence (SUI) has declined because of controversies. However, there is little evidence on the long-term prevalence of MUS reoperation. The aim of this study was to examine long-term removal and reoperation rates among…
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Artikel Jurnal
Integration of Darolutamide in the Treatment Landscape for Metastatic Hormone-sensitive Prostate Cancer: A Systematic Review and Network Meta-analysis of Efficacy and Safety
Background and objective: Recent advances have led to the introduction of multiple combination treatments for metastatic hormone-sensitive prostate cancer (mHSPC), but their comparative efficacy and toxicity remain uncertain owing to the absence of head-to-head comparisons. We evaluated the…
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