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Comprehensive Psychoneuroendocrinology
Scopus
ISSN 2666-4976 · Elsevier · 333 artikel di indeks
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Artikel Jurnal
Metabolic syndromes mediate the association between depression and cardiovascular diseases in the UK Biobank Population Study
Objective: This study aimed to assess the potential mediating role of metabolic syndrome (MetS) between depression and cardiovascular disease (CVD). Methods: This population-based prospective cohort study analyzed data collected between March 2006 and December 2010 from 353,610 participants aged 37…
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Cortisol-to-DHEAS awakening response ratio in people with dementia and family caregivers: Associations with age, dementia severity and agitation
Background: The ratio of cortisol to dehydroepiandrosterone sulfate (DHEAS) in the awakening response has emerged as a potential biomarker of stress-related dysregulation in neurodegenerative conditions. Whether this ratio differs between people with dementia (PWD) and family caregivers, and how it…
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The correlational study of the 24 solar terms and meteorological factors with the acute exacerbation of bipolar disorder
Background: Bipolar disorder (BD) is a severe mood disorder, and increasing evidence suggests that acute episodes of BD may exhibit seasonal patterns. However, the relationship between acute BD episodes and meteorological factors remains a contentious issue in academia. This study aims to…
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Association between anxiety symptoms on risky e-biking riding behavior among adolescents: based on gut-brain axis
Objective: This study aimed to investigate the association between anxiety symptoms and risky e-bike riding behavior (RERB) among adolescents and to explore whether gut microbiota mediates this relationship. Methods: Adolescents using e-bikes were recruited through a combined online and offline…
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Maternal thyroid function in the first half of pregnancy and neurodevelopmental outcomes in early adolescence in the Amsterdam Born Children and their Development (ABCD) cohort
Maternal thyroid hormone levels in pregnancy have been implicated to play a role in brain development, but few observational studies have examined their relationship with neurodevelopmental outcomes beyond early childhood. We investigated associations between maternal thyroid function during the…
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The effect of gender-affirming hormonal treatment on personality traits - a NEO-PI-R study
Introduction: Gender-affirming hormone therapy is a crucial component of the medical transition for many transgender individuals. While there are well-established differences in personality traits between cisgender men and women, the effects of gender-affirming hormone therapy on these traits in…
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Longitudinal trajectories of cancer-related cognitive impairment and influential factors among patients with lung cancer
Objective: This study aimed to investigate longitudinal cognitive changes and identify factors associated with cancer-related cognitive impairment (CRCI) among lung cancer survivors. Methods: Cognitive function was assessed using the FACT-Cog (subjective) and TICS-M (objective). The baseline…
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Exploring the mediating roles of diet and physical activity in the association between different obesity phenotypes and risk of depression: A cox survival analysis approach
Although obesity has been linked to an increased risk of depression, the risk associated with different obesity phenotypes remain unclear, as does the role of lifestyle behaviors. Participants from the UK Biobank who were free of depression at the baseline and had complete data on body composition…
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Hair cortisol concentration and basal heart rate variability differentiate long COVID from depressive disorders in youth
Depressive symptoms are highly prevalent in long COVID (LC) and may shape its symptom burden. As hypothalamic–pituitary–adrenal (HPA) axis and autonomic nervous system (ANS) alterations have been implicated in both LC and depressive disorders, this overlap raises the question of whether both…
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Maternal stress is associated with oral microbiota diversity patterns in pregnant women in Quito, Ecuador
Background: Psychological stress is present in almost all pregnancies and contributes to maternal and fetal physiology. Human microbiota is dynamic and highly responsive to maternal stress. Aims: To characterize maternal stress levels and their association with oral microbiota diversity patterns in…
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Hair cortisol and cortisone and psychological well-being: an analysis of the English Longitudinal Study of Ageing
Objectives: The study aimed to investigate the cross-sectional association of hair cortisol and cortisone with multiple dimensions of psychological well-being in older adults. Methods: A cross-sectional analysis was conducted in 3899 participants aged ≥ 50 who provided hair samples in wave 6…
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Afternoon salivary cortisol shows no association with same-day state anxiety in community-dwelling older adults during the COVID-19 pandemic
Objectives: Older adults experienced measurable psychological burden during the COVID-19 pandemic. Although salivary cortisol is widely used as a biomarker of hypothalamic–pituitary–adrenal axis activity, single time-point basal measurements may show inconsistent associations with anxiety. We…
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Justify your disability! A simulated medical evaluation as a novel stress induction model in chronic pain
Maladaptive stress responses may exacerbate chronic widespread pain (CWP) and deserve further investigations. Yet, existing stress induction paradigms lack relevance for individuals with CWP. Patients often report intense stress in response to medical appointments due to the experience of stigma…
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The oxytocinergic system in functional neurological disorder: Preliminary testing of associations with interoception and childhood trauma
The oxytocinergic system has been proposed as a vulnerability factor in the pathophysiology of Functional Neurological Disorder (FND), a condition associated with stressful life-events and disturbed bodily awareness. Recent work from our group demonstrated reduced interoceptive function alongside…
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Pupil size as a sensitive marker of acute stress dynamics
The aim of this study was to investigate pupil size as a sensitive and immediate marker of acute stress, by analyzing its evolution in response to two different stress-inducing cognitive tasks aiming to elicit distinct stress responses: a traditional Stroop task and a socially evaluative…
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Testosterone in patients with borderline personality disorder: from hair analyses to social behavior
Clemens Kirschbaum provided the important inspiration for our team to extend the assessment of steroid hormones beyond blood and saliva samples to include hair analyses. This enabled the investigation of the effects of long-term, cumulative steroid hormone secretion. This novel methodological…
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The influence of glucose intake and psychosocial stress on food craving in healthy adults
Stress has been linked to the consumption of palatable food and may contribute to the development of obesity. Interindividual differences in cortisol stress reactivity are discussed as mediating mechanisms, yet findings linking food craving to cortisol reactivity are heterogeneous. Methodological…
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Hair cortisol and other analytes continue to decline and show reduced stability after two years of storage: Follow-up data from a systematic within-subject investigation
Background: We recently highlighted pre-analytical storage duration over a one-year period as an important methodological influence on hair endocrine data. Here, we extend these findings using a 24-month follow-up of our systematic intra-individual investigation, examining mean-level changes and…
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Glucose as fuel for HPA axis regulation: A narrative review on energy metabolism, stress reactivity, and early life adversity
Stress physiology and energy metabolism are inherently linked. While the physiological stress response mobilizes energy, early experimental work by Clemens Kirschbaum and colleagues demonstrated that glucose availability in turn shapes the stress response: Fasting attenuates cortisol reactivity…