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The Lancet. Healthy Longevity
Scopus
ISSN 2666-7568 · Elsevier · 347 artikel di indeks
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Artikel Jurnal
Effectiveness of digital health technologies for post-discharge follow-up and management in older adults: a systematic review
Summary: Older adults (≥65 years) are a rapidly growing population that are experiencing a higher number of hospitalisation admissions, longer hospital stays, and greater hospitalisation-related costs than younger adults. There is an important gap in post-discharge care for older adults, and…
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Artikel Jurnal
Frailty, clinical outcomes, and treatment effects of a care bundle in acute intracerebral haemorrhage: a post-hoc analysis of the INTERACT3 trial
Summary: Background: Frailty has been widely associated with poor outcomes in mixed stroke cohorts, but evidence specific to intracerebral haemorrhage, particularly from settings in low-income and middle-income countries and regarding treatment-effect modification, remains scarce. We aimed to…
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Artikel Jurnal
Supervised multimodal prehabilitation of older patients with frailty or prefrailty before elective surgery: a multicentre randomised controlled outcome assessor-blinded trial
Summary: Background: Frailty is an increasing perioperative risk in our ageing society, and prehabilitation can mitigate this vulnerability. This trial aimed to investigate if a multimodal, individualised prehabilitation programme could maintain independence and avoid further deterioration of…
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Artikel Jurnal
Community-acquired pneumonia in adults: acute and long-term complications
Summary: Annually, community-acquired pneumonia (CAP) affects millions of individuals worldwide, resulting in more than 200 000 hospital admissions in England alone. CAP is a major cause of morbidity and mortality. Previous studies have explored the causes, risk factors, and the clinical course of…
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Artikel Jurnal
Reframing sarcopenia as a disease of the ageing motor system
Summary: Sarcopenia is a major driver of disability, frailty, and loss of independence in ageing populations. Current consensus definitions have shifted from low muscle mass to low muscle strength and impaired physical performance as the defining clinical features. The underlying disease model…
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Artikel Jurnal
Effectiveness of high-dose versus standard-dose influenza vaccines against hospitalisation according to frailty risk: a prespecified analysis of the randomised trial DANFLU-2
Summary: Background: Frailty is a major risk factor for influenza-related complications and can influence vaccine effectiveness. We aimed to assess the relative vaccine effectiveness (rVE) of high-dose (HD-IIV) versus standard-dose inactivated influenza vaccine (SD-IIV) in older adults aged 65…
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Artikel Jurnal
Spinal versus general anaesthesia and serious complications in older patients undergoing hip fracture surgery in Germany: a multicentre randomised clinical trial
Summary: Background: Evidence on the optimal anaesthetic technique for hip fracture surgery is scarce. We evaluated the effects of spinal versus general anaesthesia on all-cause mortality and new-onset serious cardiac and pulmonary complications in older patients undergoing hip fracture surgery…
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Artikel Jurnal
Addressing the growing burden of musculoskeletal diseases in the ageing US population: challenges and innovations
Summary: The prevalence of musculoskeletal diseases such as osteoarthritis, osteoporosis, sarcopenia, and rheumatoid arthritis is rising sharply with global ageing, increasing disability rates among older adults (aged ≥60 years), diminishing quality of life, and burdening health-care systems…
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Artikel Jurnal
Area-level socioeconomic inequalities in activities of daily living disability-free life expectancy in England: a modelling study
Summary: Background: More evidence of socioeconomic inequalities in disability-free life expectancy (DFLE) is needed to help develop approaches to narrow the gap between the most and least socioeconomically deprived people. Activities of daily living (ADL) disability represents the most severe and…
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Artikel Jurnal
Potential interactions of community-based acute care teams on the frequency of acute contacts with health-care systems: an interrupted time series analysis
Summary: Background: Ageing populations necessitate innovative approaches to health-care services. In 2018, Denmark introduced statutory municipal acute nursing care as part of community-based health care to improve care for adults with complex health needs. We evaluated the potential interactions…
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Artikel Jurnal
The effect of China’s Integrated Medical and Social Care Policy on functional dependency and care deficits in older adults: a nationwide quasi-experimental study
Summary: Background: With population ageing, the development and implementation of pragmatic care strategies for older people with functional dependencies have become critical issues. In alliance with WHO’s Integrated Care for Older People framework, China implemented the Integrated Medical and…
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Artikel Jurnal
Metformin and physical performance in older people with probable sarcopenia and physical prefrailty or frailty in England (MET-PREVENT): a double-blind, randomised, placebo-controlled trial
Summary: Background: Metformin has effects on multiple biological systems relevant to ageing and has been posited as a candidate therapy for sarcopenia and physical frailty. We aimed to test the efficacy and safety of metformin, a candidate geroprotector, to improve physical performance in older…