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Glomerular Diseases, Pp 1-18 (2026)
Scopus
ISSN 2673-3633 · Karger Publishers · 157 artikel di indeks
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Artikel Jurnal
Prognostic Value of Baseline and Early Proteinuria Changes in IgA Nephropathy: A U.S. Cohort Study
Introduction: Proteinuria is a key marker in IgA nephropathy (IgAN). However, long-term thresholds and significance of early changes in proteinuria remains unclear in U.S. populations. Methods: Retrospective cohort study of 745 adult patients with IgA nephropathy from the TriNetX U.S. network…
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Artikel Jurnal
Renal Histopathology and Outcomes of ANCA-Associated Glomerulonephritis: The Qatar Experience
Introduction: Anti-neutrophil cytoplasmic antibody (ANCA)–associated vasculitis is a severe small-vessel vasculitis with substantial morbidity. Data from the Gulf region are limited, restricting understanding of disease patterns and outcomes. This study describes the epidemiology, clinical…
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Artikel Jurnal
Acute Care Visits and Subsequent Health-Related Quality of Life among Children and Adults with Glomerular Disease in the Cure Glomerulonephropathy (CureGN) Cohort
Introduction: Health-related quality of life (HRQOL) is an important patient-reported aspect of overall health and is understudied in patients with glomerular disease (GD). Conflicting data have emerged regarding whether acute care visits (ACV) are associated with HRQOL. This report describes types…
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Artikel Jurnal
Cardiometabolic risk, evaluation and control in lupus nephritis
Aim: Lupus nephritis (LN) is associated with atherosclerotic cardiovascular disease but early recognition of cardiometabolic risk in patients with LN can facilitate risk optimization with disease-modifying strategies. To identify potential gaps in cardiometabolic risk management in LN in real-world…
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Artikel Jurnal
Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposits: An Immunologic Crossroads
Background: Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) is largely regarded as a form of monoclonal gammopathy of renal significance; however, 70–80% of cases lack evidence of an associated monoclonal lymphoproliferative disorder. Emerging evidence suggests it…
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Artikel Jurnal
Global Treatment Patterns for Immunoglobulin A Nephropathy in Adults: Results from a Real-World Survey
Introduction: Data on global treatment patterns for immunoglobulin A nephropathy (IgAN) are limited. Herein, we describe real-world treatment in patients with IgAN in clinical practice across distinct global regions. Methods: This was a retrospective analysis of data from a cross-sectional…
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Artikel Jurnal
Interpretative Challenges of Variants of Uncertain Significance in Severe Treatment-Refractory Focal Segmental Glomerulosclerosis
Introduction: Steroid-resistant nephrotic syndrome (SRNS) frequently reflects an underlying monogenic podocytopathy; however, the increasing use of genomic testing has also led to frequent identification of variants of uncertain significance (VUS), complicating clinical interpretation and creating…
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Artikel Jurnal
Clinical Outcome Assessment Endpoints in Nephrotic Syndrome Drug Development: Research Partner Feedback on Patient-Centered Trial Design
Introduction: Nephrotic syndrome (NS) clinical trials often rely on biomarkers or clinical measures as primary endpoints, but these may not fully capture the treatment benefits that matter most to patients. Edema-related swelling, a central manifestation of NS, profoundly affects patients’…
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Artikel Jurnal
Health Care Resource Utilization and Productivity Impairment in Adults with Immunoglobulin A Nephropathy: A Real-World, Observational, Global Analysis
Introduction: There are limited data characterizing the health care resource utilization (HCRU) associated with immunoglobulin A nephropathy (IgAN) and its burden on patients and health care systems. Here, we describe the impact of IgAN on HCRU and productivity using nephrologist- and…
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Artikel Jurnal
Beyond Ingestion: Nasal Inhalation-Induced Aristolochic Acid Nephropathy from a Traditional Herbal Remedy – A Case Report
Introduction: Aristolochic acid nephropathy (AAN), a progressive form of interstitial nephritis, is predominantly associated with the oral ingestion of herbal remedies containing aristolochic acid (AA). Case Presentation: This report details a rare case of AAN linked to nasal inhalation of a…
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Artikel Jurnal
Successful Treatment of Refractory Immune Complex-Mediated Membranoproliferative Glomerulonephritis with Pegcetacoplan: A Case Report
Immune complex-mediated membranoproliferative glomerulonephritis (IC-MPGN) lacks proven targeted therapy and is often refractory to nonspecific immunosuppression. Dysregulation of the alternative complement pathway provides a mechanistic rationale for proximal C3 inhibition. This article presents…
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Artikel Jurnal
Serum Phospholipase A2 Receptor Antibody Is Associated with Thrombogenesis in Primary Membranous Nephropathy: A Systematic Review and Meta-Analysis
Introduction: Primary membranous nephropathy (PMN) is a leading cause of nephrotic syndrome in adults and is associated with an increased risk of thromboembolic events. The anti-serum phospholipase A2 receptor antibody (anti-PLA2R Ab) is highly specific for PMN, correlates with immunological…
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Artikel Jurnal
Nudging Nephrologists in Cardiovascular Risk Assessment and Management in Glomerular Diseases Treated with Immunosuppressants: An Implementation Study
Introduction: Glomerulonephritis and its treatment may be associated with cardiometabolic disease, so optimizing glycaemic and lipid control is important to mitigate cardiovascular risk. We aimed to evaluate the impact of an electronic medical record (EMR)-based physician prompt on glycaemic and…
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Artikel Jurnal
Contactin-1-Associated Membranous Nephropathy after Multiple mRNA 1273 COVID-19 Vaccinations: A Case Report
Contactin-1-associated membranous nephropathy is a rare type of membranous nephropathy typically seen in the setting of chronic inflammatory demyelinating polyneuropathy. Here we present a case of a 79-year-old man who presented with ankle edema and was found to have 2,888 milligrams of proteinuria…
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Artikel Jurnal
An “All-in-One” Kidney Biopsy in AIDS: Crescentic Immune Complex-Mediated Glomerulonephritis, CD8-Driven Interstitial Nephritis, and Superimposed Thrombotic Microangiopathy
Introduction: Human immunodeficiency virus (HIV)-associated kidney disease encompasses a diverse spectrum of glomerular, tubulointerstitial, and vascular pathologies. While HIV-associated nephropathy and immune complex-mediated glomerular disease in the setting of HIV are well-recognized entities…
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Artikel Jurnal
Prediabetes in Children and Adults with Glomerular Disease
Introduction: Glomerular disease (GD) and diabetic nephropathy are both leading causes of end-stage kidney disease (ESKD) in the USA. Much is known about each individually, but less of any interactions between the two. There is emerging evidence that factors specific to GD, such as…
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Artikel Jurnal
Crescentic IgM-κ Monoclonal Immunoglobulin Deposition Disease with Thrombotic Microangiopathy in Waldenström’s Macroglobulinemia: A Rare and Aggressive Monoclonal Gammopathy of Renal Significance Presentation – A Case Report and Literature Review
Introduction: Monoclonal immunoglobulin deposition disease (MIDD) is a rare monoclonal gammopathy of renal significance (MGRS) characterized by linear, non-organized deposition of immunoglobulin fragments along glomerular, tubular, and vascular basement membranes. While light and heavy chain MIDDs…
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Artikel Jurnal
Clinical Remission as a Function of Exposure to Cyclophosphamide in Patients with Primary Membranous Nephropathy: A One-Year Cohort Study
Introduction: Primary membranous nephropathy (pMN) is a leading cause of nephrotic syndrome (NS) in adults. Cyclophosphamide (CYC) with glucocorticoids (GCs) is recommended for high and very high-risk patients, but the optimal treatment duration and cumulative dose remain unclear. This study aimed…
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Artikel Jurnal
Examining Referral Pathways for Patients with Hematuria: A Real-World Retrospective Analysis
Introduction: Follow-up for hematuria, often found incidentally on urinalysis, is critical as it may be an early sign of glomerular disease or malignancy. We evaluated nephrology and urology referral patterns for outpatients with hematuria, and factors associated with nephrology and urology…
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Artikel Jurnal
Case Series of the Combination of Voclosporin and Belimumab Treatment of Lupus Nephritis
Introduction: Lupus nephritis (LN) remains challenging with high treatment failure and relapse rates. Current therapies often fail to achieve sustained renal remission. The objective of this research was to assess the safety and clinical effectiveness of dual therapy using voclosporin and belimumab…