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Transplantology
Scopus
ISSN 2673-3943 · MDPI AG · 185 artikel di indeks
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Artikel Jurnal Teks lengkap
Lung Allograft Size Matching in Transplantation: From Global Metrics to Imaging-Based Approaches
Accurate donor–recipient allograft size matching remains a critical determinant of outcomes in lung transplantation, yet current approaches rely predominantly on predicted total lung capacity (pTLC) and height-based metrics derived from population-based equations. These simplified surrogates fail…
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Immunotherapy for Recurrent Hepatocellular Carcinoma After Liver Transplantation: Current Evidence and Challenges
Background/Objectives: Hepatocellular carcinoma (HCC) frequently develops in the set-ting of chronic liver disease, and liver transplantation (LT) represents the most effective curative option for selected patients. Despite advances in patient selection and surveillance, HCC recurrence after LT…
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Parathyroid Hormone Levels at Transplant and Outcomes in Renal Transplant Recipients: A Single-Center Retrospective Study
Background: Patients with end-stage kidney disease commonly develop hyperparathyroidism, which may impair muscle strength and physical function. Elevated parathyroid hormone (PTH) levels have been associated with weakness and poor Timed Up and Go (TUG) test performance. We hypothesized that…
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Early vs. Late Extubation After Bilateral Lung Transplantation: Predictors and Outcomes
Background: Early extubation after bilateral lung transplantation (LT) may reduce intensive care unit (ICU) complications, but evidence from heterogeneous real-world cohorts and of its impact on mid-term functional recovery remains limited. Methods: We conducted a single-centre observational study…
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Clinical Impact of De Novo Donor-Specific HLA Antibodies on Early Kidney Allograft Outcomes: A Prospective Single-Center Cohort Study
Background: De novo donor-specific antibodies (dnDSA) are associated with impaired allograft outcomes and the development of acute and chronic antibody-mediated rejection. However, their clinical impact during the early post-transplant period remains incompletely characterized. Methods: In this…
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One-Year Outcomes of Kidney and Liver Transplantation from Drug Overdose Donors Before and During the COVID-19 Pandemic
Introduction: During the COVID-19 pandemic, drug overdose deaths increased significantly, providing a potential cohort of donor organs. However, graft failure and mortality rates among those receiving organs from donors who died from drug overdose related to the pandemic have not previously been…
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A Review of Risk Assessment in the Evolving Heart Transplant Landscape
Heart transplantation remains a vital therapy for patients with end-stage heart failure, yet organ scarcity and evolving allocation policies necessitate robust risk prediction models to optimize outcomes and equity. This narrative review explores the current landscape of risk assessment in heart…
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Inflammatory and Immune Pathways in Kidney Transplant Rejection: Current Evidence and Future Perspectives
Kidney transplantation remains the optimal treatment for end-stage renal disease, yet long-term allograft survival has plateaued due to persistent rejection. This review provides a comprehensive overview of the inflammatory and immune pathways implicated in kidney allograft rejection, integrating…
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Update on Kidney Tranplantation in Regard to ABO-Incompatible Blood Groups
Kidney transplantation is considered the best therapeutic option for patients affected by end-stage renal failure, but this possibility is limited by a shortage of donors. Living-donor kidney transplantation (LDKD) is a valuable option, frequently limited by immunological incompatibility between…
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Comparing the Effectiveness of Different Tacrolimus-Containing Medications Used in Daily Patient Care of Adult Kidney Transplant Patients in Transplant Centres of Eastern Hungary in a Prospective Non-Interventional Study (DeSz Study)
Background/Objectives: Given the narrow therapeutic range of tacrolimus and substantial inter-individual variability in trough levels, both total daily dose and the trough level-to-dose ratio are commonly used to guide dose optimization. In this study, Life-Cycle Pharma tacrolimus was compared with…
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99mTc-MAG3 Scintigraphy Within 48 h of Kidney Transplantation Predicts Long-Term Graft Survival: A Retrospective Single-Center Cohort Study
Background/Objectives: Renal scintigraphy with 99mTc-MAG3 is a non-invasive tool for assessing early post-kidney-transplant function and detecting complications. While its utility in predicting delayed graft function (DGF) is established, evidence regarding its capacity to predict long-term graft…
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Relationship Between Numbers of Patients Registered and Procedures Performed at Lung Transplantation Centers in Japan
Background: Recently, there has been a dramatic increase in deceased lung transplantation (DLT) procedures performed in Japan. However, there is concern that the number of transplantations may reach the limit of capacity in some centers. The present study was conducted to analyze the relationship…
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Macronutrient Supplementation During Prolonged Normothermic Incubation Increases Mitochondrial Function of Precision-Cut Kidney Slices After Ischemia
Background/Objectives: Kidneys from marginal donors are more susceptible to ischemia–reperfusion injury (IRI). To diminish the deleterious effects of IRI, mitochondria should be preserved optimally between donation and transplantation. It is unknown which macronutrients are imperative to support…
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Availability of Different Related Stem Cell Donors and Outcomes After Allogeneic Transplantation: A Single-Center Experience (2019–2024)
Background: In countries lacking donor registries, related donors, including haploidentical ones, often serve as the main option. This research aimed to examine the feasibility of locating donors for allogeneic hematopoietic stem cell transplants and to assess the outcomes associated with various…
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Alemtuzumab-Associated Accommodative Spasm in a Renal Transplant Recipient: A Case Report of a Rare Neuro-Ophthalmic Complication
Background: Alemtuzumab is a recombinant DNA-derived humanized monoclonal antibody directed against the 21–28 kd cell surface glycoprotein, CD52. Alemtuzumab is used as an organ anti-rejection therapy in transplant recipients. Neuro-ophthalmic adverse effects are rarely described, and, to our…
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Risk Factors for Incisional Hernia After Kidney Transplantation: Impact of Fascial Closure Suture Type
Background/Objectives: Incisional hernia (IH) is a frequent complication after kidney transplantation, with its risk influenced by both patient-related factors such as obesity, diabetes mellitus, and smoking, and procedure-related factors including surgical technique and immunosuppressive therapy…
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Analysis of Publications Related to Nursing Care in Patients Who Experience Organ and Tissue Transplantation Using the Bibliometric Method
Background: This study was conducted to guide researchers by providing a global macroscopic perspective on the main characteristics of publications on nursing care in patients undergoing organ and tissue transplantation. Methods: The data obtained from the Web of Science (WoS) database in light of…
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Dual, Split and Multi-Graft Liver Transplantation: Surgical Strategies to Maximize Liver Utilization
Liver graft shortage remains a major limiting factor in contemporary liver transplantation, particularly in the setting of increasing waiting list pressure and constrained donor availability. While the biological quality of donor organs cannot be modified surgically, several operative strategies…
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Early Graft Loss in Solitary Pancreas Transplant Recipients Within Eurotransplant Region
Introduction: While extensive research has been conducted on specific factors affecting transplant outcomes in simultaneous pancreas-kidney recipients, less is known about outcomes following single pancreas transplantation (PTx). This study focuses on identifying factors related to early graft loss…
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Calycovesicostomy, Ureterocalycostomy, and Ileocalycostomy: Rare Reconstructive Options for Transplant Ureteral Strictures
Background: Transplant ureteral stricture (TUS) reconstruction remains a significant challenge in renal transplantation, particularly when conventional access to the transplant ureter and renal pelvis is not feasible. This report presents two rare and complex surgical reconstructions: a combined…