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Frontiers in Pain Research
Scopus
ISSN 2673-561X · Frontiers Media S.A. · 1.073 artikel di indeks
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Artikel Jurnal
Exploring post-operative pain management practices for improved outcomes among nurses in public hospitals in West Shewa, Ethiopia: a multicenter observational study
BackgroundEffective postoperative pain (POP) management is crucial to enhance satisfaction and recovery. Nurses play a significant role in providing effective pain management, making it crucial to assess their practices. However, most prior research in Ethiopia relied on self-administered tools to…
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Artikel Jurnal
Time-course based assessment of patient factors and their relationship to chemotherapy induced peripheral neuropathy
BackgroundPatients commonly experience chemotherapy-induced peripheral neuropathy (CIPN) as an adverse effect from chemotherapies, such as taxanes. In some patients, CIPN symptoms are severe and significantly impact their quality of life. Gaining a deeper understanding of how patient factors change…
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The nonhallucinogenic ketamine metabolite (2R,6R)-hydroxynorketamine is a novel analgesic in animal models of pain
Current treatment options for acute and chronic pain provide limited efficacy and safety. There is an urgent need to develop drugs with new, non-opioid treatment strategies that produce fewer adverse consequences. Preclinical evidence across multiple models of acute and chronic pain demonstrate…
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The role of transcutaneous auricular vagus nerve stimulation in chronic pain: from neurobiological mechanisms to clinical applications
Chronic pain is a prevalent health issue with high disability rates, and traditional pharmacological treatments often come with limitations such as dependency and side effects. Transcutaneous auricular vagus nerve stimulation (taVNS), as an emerging non-invasive neuromodulation technique, has…
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Barriers and facilitators to implementing immersive virtual reality in long-term care settings: an interdisciplinary partnership study exploring staff perspectives
IntroductionImmersive virtual reality (VR) has attracted growing interest in long-term care (LTC) as a potential tool to enhance well-being and alleviate pain. However, its effective implementation by LTC staff remains understudied. In a participatory action, mixed-methods study co-developed with…
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Artikel Jurnal
OPRM1 gene polymorphism linked to anxiety in cancer-related pain patients: an observational study
IntroductionAnxiety is common in patients with cancer-related pain, affecting an increasing number of individuals annually and negatively impacting prognosis. Limited methods are available for early identification of anxiety in these patients. This study explores the link between the OPRM1 gene's…
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Artikel Jurnal
Chronic pain in transgender and gender-diverse youth: a biopsychosocial perspective
Chronic pain—including both chronic primary pain (e.g., headaches, widespread musculoskeletal pain, abdominal pain) and chronic secondary pain associated with other health conditions—represents a significant yet underrecognized health concern among transgender and gender-diverse (TGD) youth. While…
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Medication overuse headache: position statement of specialized headache centers in Brazil
ObjectiveTo develop a position statement based on expert opinions for the management of medication overuse headache (MOH) in Brazil.MethodThis was an observational, prospective, descriptive, and opinion-based study. The experts were in several Brazilian states. Twelve experts who fulfilled the…
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Artikel Jurnal
Treating chronic pain with low dose ketamine and adjunct therapies within a biopsychosocial approach: a case series
Chronic pain is an individual experience with physical and psychological dimensions. Ketamine is used in sub-anesthetic doses to treat chronic pain. We describe a proposed multidisciplinary approach with combined treatment of low-dose ketamine and pain-focused psychological and somatic therapies to…
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Long-term efficacy of neuromodulation in chronic pain management: a single-center retrospective study
ObjectivesNeuromodulation is an advanced therapy for managing chronic pain by modulating nerve activity through electrical stimulation. This study evaluates the clinical outcomes of neuromodulation therapies, including spinal cord stimulation (SCS), occipital nerve stimulation (ONS), and peripheral…
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Artikel Jurnal
Decoding chronic pain: integrating genetics, neuroimaging, and AI for precision management
Chronic pain is increasingly recognised as a standalone medical condition shaped by interacting biological, psychological, and social determinants, affecting nearly one in three adults worldwide. This review synthesises contemporary evidence on the epidemiology, mechanisms, and management of…
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Artikel Jurnal
The information that patients, their families, and medical staff wish to know about postoperative pain and its management. Results of the survey after mixed surgical procedures
BackgroundInforming patients and families about perioperative pain management is a fundamental element of care. However, patients and their families are often not involved developing such resources. Thus, their viewpoints on content, timing, and methods of presentation remain unknown. Our survey…
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Impact of therapeutic exercises on pain-related outcomes in patients with knee osteoarthritis: an umbrella review of 116 systematic reviews
Background and objectivesChronic knee pain is highly prevalent in various knee diseases. It significantly decreases patients’ quality of life. Among non-surgical interventions, exercise is considered a promising approach for alleviating chronic knee pain. This umbrella review aimed to…
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A tonic electrocutaneous stimulation paradigm for graded sensory C-fiber engagement in healthy subjects
IntroductionLong-term pain models provide valuable proxies for studying physiological changes associated with chronic pain, which is commonly associated with sustained C-fiber-mediated nociceptive input and central sensitization, and are particularly useful in therapeutic and drug development…
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Beyond nociception: rethinking pain in ovarian endometriosis a pilot study
BackgroundEndometriosis affects 1 in 10 women, is the most common cause of chronic pelvic pain, classically known for its nociceptive pain mechanisms. Medical therapies have limited efficacy, prevent pregnancy, and can be poorly tolerated in over 30% of cases. Meanwhile, surgical management can be…
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Artikel Jurnal
Integrated multi-omics elucidates the dual anti-inflammatory and neuroendocrine mechanisms of novel TCM plasters against primary dysmenorrhea
BackgroundPrimary dysmenorrhea (PD) is a prevalent gynecological condition primarily driven by uterine inflammation and hormonal imbalances. While non-steroidal anti-inflammatory drugs (NSAIDs) are the first-line treatment, their side effects and failure rate necessitate alternative therapies. The…
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Behavioral assessment of pain in rodents: advances from evoked responses to spontaneous states and multimodal approaches
Pain is widely recognized as a leading global health problem that markedly diminishes quality of life. Although assessment lies at the core of pain medicine, robust quantification remains difficult. In preclinical research, commonly used behavioral assays often blur the distinction between…
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Artikel Jurnal
Efficacy and safety of Tai Chi for chronic musculoskeletal pain: a systematic review and meta-analysis
ObjectivesTai Chi, a form of complementary intervention emphasizing breathing and mind-body connection, is increasingly recognized for its potential in pain management. This review aims to synthesize current evidence on the efficacy and safety of Tai Chi for chronic musculoskeletal pain management…
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Artikel Jurnal
High impact chronic pain in children: exploration of associated characteristics and clinical factors in children and parents
BackgroundChronic pain in children can significantly impact daily functioning. While interdisciplinary pain rehabilitation is the recommended treatment, it is resource-intensive and limited in availability. Therefore, children with more complex symptoms, classified as High Impact Chronic Pain…
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Artikel Jurnal
Participant perspectives on a multimodal program for neuropathic pain after spinal cord injury
IntroductionSpinal cord injury (SCI) results in several medical consequences. While some of these are immediate, others, like chronic pain, may emerge after weeks or months. Roughly 60% of individuals develop persistent neuropathic pain within the first year after injury. Due to the limited…
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