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Frontiers in Tropical Diseases
Scopus
ISSN 2673-7515 · Frontiers Media S.A. · 310 articles in the index
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Journal Article
Reduced bio-efficacy of aged PermaNet® 3.0 Nets against local pyrethroid-resistant Anopheles arabiensis in Western Kenya
BackgroundLong-lasting insecticidal nets (LLINs) are central to malaria control and designed to protect for up to three years; however, increasing pyrethroid resistance undermines their effectiveness. Piperonyl butoxide (PBO) LLINs, designed to enhance pyrethroid efficacy, are recommended in…
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Journal Article
Position paper on the management of antithrombotic therapy in patients with dengue
Dengue is endemic in more than 100 countries, primarily affecting tropical and subtropical regions, including Argentina. Between epidemiological weeks (EW) 1 and 47 of 2024, the Region of the Americas reported a cumulative incidence of 1,327 cases per 100,000 inhabitants, representing a 197%…
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Journal Article
The potential of interferon-gamma in the regulation of hTERT expression: insights into telomere dynamics and immune activation in malaria
Malaria remains a significant burden to public health, causing an estimated 282 million new cases in 2024 alone. Recurrent infections and increasing antimalarial resistance contribute to weakening immunity, a process that includes accelerated cellular ageing in immune cells, associated with…
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Journal Article
A spatio-temporal analysis of climate variability and a selected zoonotic disease distribution in Binga District, Zimbabwe. A quantitative research protocol
IntroductionClimate warming in the coming years is anticipated to greatly influence the relationships between pathogens and their animal and human hosts. Vector-borne illnesses are particularly vulnerable to rising temperatures, as temperature changes can modify development rates, geographical…
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Journal Article
Evaluating delivery models for mass dog vaccination: a cost-effectiveness analysis of community-led and team-led vaccination strategies for rabies control in resource-limited settings
IntroductionRabies is a fatal but preventable zoonotic disease that is still endemic in many low- and middle-income countries. Mass dog vaccination is central to rabies control, but identifying delivery strategies that are both effective and economically feasible continues to be a challenge in…
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Journal Article
Factors that influenced the delivery of a community-based continuous mass dog rabies vaccination approach in the Mara region of Tanzania
IntroductionMass dog vaccination is the most effective approach for interrupting canine rabies transmission. However, current vaccination strategies are typically centralized and conducted annually, leaving some communities excluded and with few opportunities to vaccinate their dogs. A…
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Journal Article
Experiences of piloting integrated bite case management in Zaria Metropolis, Nigeria
BackgroundRabies remains a major public health risk in Africa and is estimated to cause over 1,600 deaths annually in Nigeria. Integrated Bite Case Management (IBCM) is recommended as a One Health approach for rabies surveillance but has yet to be implemented within Nigeria.MethodsOur aim was to…
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Journal Article
Operationalising people-centred community-led self-help groups to improve mental health and wellbeing for people with skin-neglected tropical diseases: a case study from Kasai, DRC
IntroductionPeople affected by skin-neglected tropical diseases (NTDs) may experience stigma and discrimination due to visible physical impairments, negatively affecting their mental health, wellbeing, and quality of life. To address these challenges, our partnership used a community-based…
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Journal Article
Artificial intelligence-supported One Health surveillance for early warning of Rift Valley fever in Senegal
BackgroundRift Valley Fever (RVF) is a zoonotic disease affecting humans and livestock across Africa, with outbreaks influenced by ecological, animal, and social factors. In Senegal, nomadic livestock systems, endemic mosquito vectors, and mobile pastoralist communities create recurrent outbreak…
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Journal Article
Case report: Clinical presentation of imported cases of dengue: a case series
Dengue is the most common viral disease transmitted by mosquitoes, widely distributed in tropical and subtropical regions. Dengue is a growing global health problem due to its rapid spread and increasing number of cases in recent decades. The disease is now endemic in over 100 countries, putting a…
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Journal Article
Community self-care, prevention practices, and treatment-seeking behaviors related to malaria: a qualitative study grounded in Orem’s self-care deficit theory in Malanje, Angola
BackgroundMalaria remains a major public health problem in Angola, where sustained transmission persists despite expanded access to preventive and therapeutic interventions. Understanding community self-care practices is essential to improving malaria control in endemic settings.ObjectiveTo explore…
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Journal Article
Designing a focused and impact-oriented second strategic National Action Plan for Health Security in Sierra Leone, 2025: process, best practices, and lessons learned
IntroductionThe National Action Plan for Health Security (NAPHS) is a country-owned, whole-of-government, and all-hazards strategic plan for strengthening health security. In 2025, Sierra Leone developed its second NAPHS (2025–2029). We share the process, lessons learned, and best practices adopted…
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Journal Article
Dengue management using an Ecohealth approach: implementation analysis in Cali, Colombia (2020–2023)
Dengue is a public health event that impacts communities and can result in death. Countries have joined forces to address this public health issue using various approaches, strategies, and methodologies to mitigate its socioeconomic and health impacts. In the city of Cali, Colombia, the Health…
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Journal Article
Chromoblastomycosis in resource-limited settings: a review
Chromoblastomycosis is a chronic skin-related neglected tropical disease caused by melanized (dematiaceous) fungi, predominantly from the Fonsecaea and Cladophialophora species. The disease primarily affects individuals in tropical and subtropical areas, especially those engaged in soil-related…
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Journal Article
Diagnostic performance of digital and clinical approaches for detection of podoconiosis by community health workers in Rwanda: a comparison with dermatologist diagnosis
IntroductionDetection of podoconiosis is essential to prevent disability, but diagnostic challenges mean it often goes unnoticed in Rwanda, leading to irreversible harm and social stigma.MethodsThis study evaluates the diagnostic performance of the WHO Skin-NTD mobile application and a clinical…
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Journal Article
Perceived barriers to Aedes aegypti larval habitat control among surveyed residents in five Panamanian districts: a cross-sectional health belief model analysis
BackgroundHousehold source reduction remains central to Aedes aegypti control, but reported intention may coexist with practical and contextual barriers. We examined perceived barriers and related Health Belief Model (HBM) constructs among surveyed residents of five Panamanian districts.MethodsThis…
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Journal Article
Underrepresentation of African surveillance data in global arbovirus modeling
Recent expansion of arboviruses across Europe has intensified efforts to understand the ecological and environmental drivers of pathogen emergence. However, global interpretations of arbovirus dynamics remain disproportionately informed. Global interpretations of arbovirus dynamics remain…
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Journal Article
Contemporary challenges of Schistosomiasis mansoni in Brazil: a review of epidemiological indicators, SUS protocols, and control strategies (2010–2026)
This scientific review analyzes the contemporary epidemiological landscape and public health management of Schistosomiasis mansoni in Brazil for the 2024–2026 triennium. The main objective of this study is to provide multiple diagnostic and environmental engineering dimensions, extending beyond…
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Journal Article
Dengue in an era of hyperendemicity: clinical triage, case management, and primary care preparedness in resource-constrained settings: a narrative review
Dengue is placing increasing pressure on frontline health services as recurrent transmission, co-circulating serotypes, and expanding outbreaks generate large volumes of clinically similar febrile illnesses. Although most infections remain uncomplicated, deterioration may occur rapidly around…