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Frontiers in Ophthalmology
Scopus
ISSN 2674-0826 · Frontiers Media S.A. · 480 articles in the index
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Journal Article
Ocular ischemic syndrome secondary to carotid artery disease: a comprehensive review addressing critical early detection, management, and education
PurposeThis study was conducted to emphasize the significance of early detection of ocular ischemic syndrome (OIS), indicating advanced carotid atherosclerotic occlusive disease and preceding life-threatening ischemic cerebrovascular events, and to boost education in eyesight care.MethodsA…
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Journal Article
Periocular necrotizing fasciitis
Necrotizing fasciitis is a rapidly progressive infection commonly associated with group A Streptococci and other toxin-producing bacteria that leads to microvascular thrombosis, tissue ischemia, and fascial plane spread. Although the periorbital region’s rich vascularity and natural anatomic…
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Journal Article
The role of optical coherence tomography in the evaluation of para-chiasmal lesions: a systematic review and meta-analysis
IntroductionWhile magnetic resonance imaging is currently the primary diagnostic tool for pituitary tumors, optical coherence tomography (OCT) may be used in evaluating the visual pathway impact of these lesions. This study evaluates the utility of OCT in patients with chiasmal compression from…
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Journal Article
Clinical and economic impacts of optical coherence tomography prior to cataract surgery in a low-to-middle-income country
BackgroundIntegrating optical coherence tomography (OCT) into the pre-surgical stage of cataract management holds significant clinical and economic potential, particularly in low-to-middle-income countries like Kazakhstan.ObjectiveThis study aimed to evaluate these impacts by prospectively…
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Journal Article
CDHR1 variants in a Japanese family with inherited retinal dystrophy and intrafamilial phenotypic variability
IntroductionTo report a Japanese family with inherited retinal dystrophy (IRD) in which CDHR1 variants were identified, and to characterize the marked intrafamilial phenotypic variability.MethodsThis retrospective case series included three brothers diagnosed with retinal dystrophy at Juntendo…
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Journal Article
Triple-hit diffuse large B-cell lymphoma with choroidal and cavernous sinus involvement mimicking inflammatory and neuro-ophthalmic disease: case report
BackgroundTo describe our findings in a rare case of secondary triple-hit diffuse large B-cell lymphoma (DLBCL) with choroidal and central nervous system (CNS) involvement, presenting with bilateral serous retinal detachments (SRD) and ophthalmoplegia.Case presentationA 44-year-old male presented…
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Journal Article
Artificial intelligence in ophthalmology: trust, bias, and responsibility from the perspective of medical students and ophthalmologists
BackgroundArtificial intelligence (AI) is increasingly integrated into ophthalmology, offering advances in diagnostic accuracy and surgical decision support. However, perceptions, trust, and ethical concerns regarding AI among medical students and ophthalmologists remain insufficiently…
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Journal Article
Case Report: Bilateral perineuroma of the orbit presenting as vertical binocular diplopia
In this case report, we describe a 65-year-old woman who presented to the ophthalmology clinic with vertical binocular diplopia for approximately 2 years. Visual exam was notable for bilateral proptosis and ophthalmoplegia. A computed tomography (CT) of the head revealed bilateral enhancing orbital…
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Journal Article
Peripapillary hyperreflective ovoid mass-like structure in arteritic versus nonarteritic anterior ischemic optic neuropathy
IntroductionA peripapillary hyperreflective ovoid mass-like structure (PHOMS) is an optical coherence tomography (OCT) specific finding associated with axoplasmic stasis in various optic neuropathies. Its occurrence in arteritic anterior ischemic optic neuropathy (A-AION) has not previously been…
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Journal Article
Transcriptomic changes in the lacrimal glands of a Sjogren’s disease animal model highlight key molecular mediators and altered biological functions underpinning glandular inflammation and hypofunction
IntroductionSjogren’s disease (SjD) is a chronic autoimmune condition that targets the lacrimal glands (LGs), resulting in aqueous-deficient dry eye disease (DED). Insufficient or low-grade tear secretion onto the ocular surface affects the normal physiology of the cornea and conjunctiva and can…
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Journal Article
Central corneal thickness, corneal endothelial cell density, and morphology in myopic eyes of young Chinese candidates for refractive surgery
PurposeTo assess central corneal thickness (CCT), as well as the density and morphology of corneal endothelial cells (ECD) in myopic eyes.MethodsA total of 400 patients scheduled for myopic refractive surgery were consecutively enrolled in this study. Preoperative evaluations encompassed…
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Journal Article
Reverse optic capture in cataract surgery: techniques, indications, and outcomes
Reverse optic capture (ROC) is a surgical technique in which the optic of an intraocular lens (IOL) is positioned anterior to the anterior capsulotomy opening, while the haptics remain within the capsular bag. Described originally as a method to secure fixation in cases of posterior capsular…
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Journal Article
Imaging and functional correlates of fibrosis in neovascular age-related macular degeneration: a systematic review
BackgroundDespite intravitreal anti–vascular endothelial growth factor (VEGF) therapy being the standard of care for neovascular age-related macular degeneration (nAMD), long-term visual decline remains common, with subretinal fibrosis representing a major cause of irreversible vision loss…
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Journal Article
“Preventing vision loss in pediatric otogenic thrombosis: a case report highlighting surgical interventions”
Otogenic cerebral venous sinus thrombosis (CVST) is a rare complication of acute otitis media in children and may lead to severe intracranial hypertension with vision-threatening papilledema. We report the case of a 4-year-old girl with otogenic CVST involving the left transverse and sigmoid…
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Journal Article
A novel retrobulbar/intraconal surgical approach with combined cataract extraction and a modified AHMED ClearPath 250mm2 tube in the ciliary sulcus with an inferior sclerotomy in black and Afro-Latino patients with advanced glaucoma: a 6-month retrospective study
AimThe purpose of this early safety and technical feasibility study was to evaluate the real-world performance of cataract extraction combined with a modified Ahmed ClearPath 250 mm² glaucoma drainage device placed in the retrobulbar/intraconal space with inferior sclerotomy in glaucoma patients…
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Journal Article
Case Report: Maculopathy following standard dose intracameral cefuroxime injection during ICL surgery
PurposeTo describe two rare occurrences of acute toxic maculopathy, specifically Intracameral Cefuroxime Ocular Toxic Syndrome (ICOTS), following uncomplicated posterior-chamber toric phakic implantable collamer lens (TICL) surgery despite the administration of a standard dosage of…
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Journal Article
Ultrasound biomicroscopy and anterior segment OCT in ocular surface squamous neoplasia: complementary roles, case series, and targeted literature review
IntroductionOcular surface squamous neoplasia (OSSN) encompasses a spectrum of epithelial malignancies of the conjunctiva and cornea that, untreated, may invade intraocularly or into the orbit. Clinical examination alone may fail to define true depth of invasion, risking under- or overtreatment…