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Archives of Basic and Clinical Research
ISSN 2687-4520 · Erzincan Binali Yıldırım University School of Medicine · 59 artikel di indeks
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Pulmonary Ischemia-Reperfusion Injury
Pulmonary ischemia-reperfusion (I/R) injury is recognized as a key factor in the development of primary graft dysfunction and remains a major cause of perioperative morbidity and mortality in both lung transplantation and thoracic surgical procedures. This type of injury encompasses several…
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Classification of Potential Risk Factors for Maxillary Sinus Membrane Perforation Using Cone-Beam Computed Tomography
Objective: To determine the frequency of anatomic variations, pathologies, and physiological alterations in the maxillary sinus, and to identify the most common combinations in which these risk factors coexist and may predispose to perforation of the maxillary sinus membrane. The relationship…
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Changes in Gastritis During the COVID-19 Pandemic: A Retrospective Comparative Study According to the Sydney Criteria
Objective: This study aimed to evaluate whether the coronavirus disease-2019 (COVID-19) pandemic caused changes in the severity of gastritis, as assessed by the Sydney criteria, through a retrospective comparison of patients in the pre- and post-pandemic periods. Methods: Pathology reports of 107…
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The Role of Serum Zinc, Iron, Magnesium, and Selenium Levels in the Pathogenesis of PFAPA Syndrome
Objective: To investigate the potential role of zinc, iron, magnesium, and selenium in the pathogenesis of Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis (PFAPA) syndrome. Methods: A retrospective analysis was conducted of 26 children diagnosed with PFAPA and 31 age- and sex-matched…
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Predictive Factors for Ureteral Stricture in Patients Undergoing Endoscopic Stone Surgery
Objective: To evaluate predictive factors for ureteral stricture in patients undergoing ureterorenoscopy (URS) for ureteral stones and to identify radiological and demographic parameters that may influence surgical access. Methods: This retrospective study analyzed data from 197 patients who…
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3D Printed Cutting Guide for Subtrochanteric Transverse Shortening Osteotomy in Total Hip Replacement for Crowe Type 4 Developmental Dysplasia
Objective: Subtrochanteric transverse femoral shortening osteotomy is a frequently employed technique to avoid potential complications in total hip arthroplasty with a high hip center. However, when performed freehand, the osteotomy may be associated with complications such as non-union…
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What Magnetic Resonance Imaging Can Miss Around the Knee? Correlation of Imaging Results with Arthroscopic Findings
Objective: Magnetic resonance imaging (MRI) is a non-invasive and extensively used diagnostic tool for evaluating intra-articular knee pathologies. Nevertheless, the diagnostic concordance between MRI and arthroscopic findings remains a matter of debate. This study aimed to assess the correlation…
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Predicting Breast Cancer Biomarker Expression with Diffusion-Weighted Magnetic Resonance Imaging
Objective: To evaluate the diagnostic performance of diffusion-weighted magnetic resonance imaging (DWI) and apparent diffusion coefficient (ADC) values in differentiating benign and malignant breast lesions, and to investigate correlations between ADC values and immunohistochemical (IHC)…
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Non-Motor Symptoms in Gabapentin Users: A Clinical Evaluation
Objective: Gabapentin is widely used for neuropathic pain, epilepsy, and other indications; however, its non-motor side effects remain understudied. This prospective, cross-sectional observational study aimed to evaluate non-motor symptoms in gabapentin users, assessed with the Non-Motor Symptom…
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The Relationship Between Allergic Reactions and Serum Erythropoietin Levels: A New Biomarker Candidate in Allergic Reactions
Objective: This study aimed to compare serum erythropoietin (EPO) levels in patients admitted to the emergency department with allergic reactions who were clinically diagnosed with urticaria, angioedema, or anaphylaxis, and to evaluate the diagnostic value of EPO as a potential biomarker. Methods…
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Diagnostic Value of Initial Laboratory Parameters in Predicting Hemothorax among Adult Patients with Isolated Blunt Thoracic Trauma Presenting to the Emergency Department: A Retrospective Observational Study
Objective: Hemothorax is a serious complication of blunt thoracic trauma requiring early recognition. While computed tomography (CT) is the diagnostic gold standard, imaging delays in unstable patients necessitate alternative early markers. This study evaluated the predictive value of initial…
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Investigation of Sensitivity and Specificity of Biochemical Markers for Cardiac Contusion due to Blunt Chest Trauma
Objective: There remains a significant need for precise biomarkers to diagnose cardiac contusion. The objective of this study is to examine the diagnostic significance of cardiac myosin-binding protein-C (cMyBP-C) in thoracic injuries, including cardiac contusion. Methods: The inclusion criteria…
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Venetoclax-Ibrutinib Combinations as First-Line Therapy in Chronic Lymphocytic Leukemia: A Meta-Analysis of Randomized Controlled Trials with GRADE Approach
Objective: Chronic lymphocytic leukemia (CLL) treatment has shifted from chemoimmunotherapy to targeted agents. Venetoclax and ibrutinib, which act through complementary mechanisms, have shown promise in achieving deep remissions. Their combination may enhance efficacy, but pooled evidence from…
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Diagnostic Effectiveness of Ischiofemoral Space and Quadratus Femoris Distance Measurements in Ischiofemoral Impingement Syndrome
Objective: To ascertain whether measurements of the quadratus femoris and ischiofemoral intervals obtained on pelvic magnetic resonance imaging (MRI) examinations are useful for diagnosing ischiofemoral impingement (IFI) syndrome. Methods: MRIs of 178 patients (104 females and 74 males) were…
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Association of Infrapatellar Fat Pad Morphology and Signal Changes with Patellar Chondromalacia
Objective: To evaluate the association between infrapatellar fat pad (IPFP) maximal area, depth, and signal intensity alterations and the presence and severity of patellar chondromalacia on magnetic resonance imaging (MRI). Methods: In this single-center retrospective study, 172 knee MRI…
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Diagnostic Performance of Dual-Source CT Angiography Compared with Echocardiography in Pediatric Congenital Heart Disease
Objective: The aim of this study was to assess the diagnostic performance and radiation dose of 128-slice dual-source computed tomography (DSCT) angiography in pediatric patients with congenital heart disease (CHD) and to compare its diagnostic accuracy with that of transthoracic echocardiography…
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Diagnostic Comparison of MRI/Ultrasound Fusion Biopsy and Systematic Biopsy in PI-RADS 4-5 Prostate Lesions
Objective: Multiparametric magnetic resonance imaging (mpMRI) has transformed prostate cancer (PCa) diagnosis by enabling lesion-targeted biopsies. The optimal biopsy approach—systematic biopsy (SB), MRI-ultrasound fusion targeted biopsy (TB), or their combination (CB)—remains debated, especially…
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Comprehensive MEFV Variant Spectrum in Pediatric Patients with Suspected Familial Mediterranean Fever: A Whole-Gene Sequencing Study
Objective: To determine the Mediterranean Fever (MEFV) variant spectrum using whole-gene next-generation sequencing (NGS) in pediatric cases with suspected Familial Mediterranean Fever (FMF). Methods: This retrospective cross-sectional study included 471 pediatric cases referred for MEFV analysis…
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Prognostic Value of Eosinophil-Derived Hematological Indices in Acute Decompensated Heart Failure
Objective: Eosinophil-derived hematological indices have been proposed as potential prognostic markers for cardiovascular disease; however, their clinical value in acute decompensated heart failure (ADHF) remains unclear. This study aimed to comprehensively evaluate the prognostic significance of…
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The Relationship Between Non-alcoholic Fatty Liver Disease and Epicardial Adipose Tissue Thickness, Carotid Intima Media Thickness, and Aortic Propagation Velocity
Objective: Cardiovascular disease is prevalent among individuals diagnosed with non-alcoholic fatty liver disease (NAFLD). Epicardial adipose tissue (EAT), carotid intima-media thickness (CIMT), and aortic propagation velocity (APV) are associated with atherosclerosis and cardiovascular disease…