444 results
Showing 1–20 · 0.27 seconds · RSS
Skin Health and Disease
Scopus
ISSN 2690-442X · Oxford University Press · 444 articles in the index
-
Journal Article
Primary vulval melanoma and genital lichen sclerosus
Abstract Background Lichen sclerosus (LS) is a chronic, inflammatory skin disease with a predilection for the genitalia. Although, the association between squamous cell cancer and genital LS is well established, a link with genital melanoma has not been thoroughly explored. However, we have…
-
Journal Article
A systematic review of outcome measures evaluating treatment efficacy in vulval lichen sclerosus and evaluation of patients' priorities
Abstract Vulval lichen sclerosus (VLS) is an inflammatory skin disease characterised by itching, apareunia, loss of vulval architecture and scarring. Heterogeneity in outcome reporting precludes comparison between treatments. This study aimed to systematically review outcome measures used to…
-
Journal Article
Skin sensing and wearable technology as tools to measure atopic dermatitis severity
Abstract Wearable medical technology encompasses a range of electronic devices that act as biosensors. Atopic dermatitis (AD) is the commonest inflammatory skin disease and represents an important area of need in which to leverage the power of wearable biosensor technology, especially as the impact…
-
Journal Article
Increased physical activity promotes skin clearance, improves cardiovascular and psychological health, and increases functional capacity in patients with psoriasis
Abstract Background Patients with psoriasis are less physically active compared to age‐matched controls, due to psoriasis‐specific barriers, which significantly limits their ability to benefit from health‐promoting levels of physical activity (PA). In addition, long‐term health outcomes for people…
-
Journal Article
Safety and efficacy of the swift microwave device in patients with mild‐to‐moderate onychomycosis: Protocol of an open‐label, randomized, dose‐finding pilot study
Abstract Background Onychomycosis is a common fungal nail disease with a prevalence rate up to 14% in North America and 24% in Europe. The current treatment paradigm is limited by a high risk of disease recurrence, safety concerns for oral agents, and a low likelihood of patients achieving both…
-
Journal Article
Applications and efficacy of minoxidil in dermatology
Abstract Minoxidil, originally developed as an antihypertensive medication, has evolved into a versatile therapeutic agent within dermatology, notably for its effectiveness in promoting hair growth. Despite its widespread use, understanding its precise mechanism of action remains a challenge. This…
-
Journal Article
Dupilumab‐associated ocular surface disease or atopic keratoconjunctivitis not improved by dupilumab? Upadacitinib may clarify the dilemma: A case report
Abstract Dupilumab‐associated ocular surface disease is a common clinical sign appearing in patients with atopic dermatitis (AD) just few months after dupilumab treatment start, developing in about 25% of patients. Atopic keratoconjunctivitis (AKC) is a well‐identified clinical entity, defined as a…
-
Journal Article
Clear cell renal cell carcinoma micrometastasis: Insights from an unconventional cutaneous presentation
Abstract Clear cell renal cell carcinoma (ccRCC) is a highly lethal cancer known for its propensity to metastasise, yet the mechanisms underlying metastasis are not well defined. Cutaneous metastases from ccRCC are uncommon and typically occur within 3 years post‐nephrectomy, predominantly…
-
Journal Article
Numerical, phenotypic and functional differences in human dermal resident memory T cells between reticular dermal layers
Abstract Background Resident memory T (TRM) cells and immunosuppressive Foxp3‐expressing regulatory TRM (regTRM) cells are present in healthy, non‐inflamed and inflamed human skin. Both types of cells are found in both the epidermis and dermis with the dermis being much thicker than the epidermis…
-
Journal Article
Impact of the COVID‐19 pandemic on international cutaneous squamous cell carcinoma incidence: A systematic review and meta‐analysis
Abstract Background Non‐melanoma skin cancer (NMSC) is the most common cancer globally in white ethinicity populations, and cutaneous squamous cell carcinoma (cSCC) is the second most common subtype. The COVID‐19 pandemic severely impacted public and private healthcare systems. Many studies have…
-
Journal Article
Expanding subcutaneous mass on the scalp of an immunocompromised woman
Abstract Acute cutaneous presentations in immunocompromised patients demand careful and thorough evaluation. Here, we present the case of a 26‐year‐old female with acute myeloid leukaemia undergoing salvage chemotherapy, who developed an acutely expanding subcutaneous mass starting on the…
-
Journal Article
Successful long‐term guselkumab treatment of severe plaque psoriasis in patients with class III obesity: A case series
Abstract Data from real‐world studies and clinical trials have documented the long‐term efficacy and safety of guselkumab in patients with moderate‐to‐severe psoriasis. Limited data are available on the long‐term use of guselkumab in morbidly obese individuals with severe psoriasis. Here, we…
-
Journal Article
Topical immunotherapy with diphenylcyclopropenone in paediatric patients with alopecia areata—A retrospective study of 97 patients
Abstract Background Alopecia areata (AA) is an autoimmune disease causing chronic non‐scarring hair loss. Different therapeutic regimens have been suggested for AA, which depend on patients' age, scalp involvement extent and duration. Topical immunotherapy with diphenylcyclopropenone (DPCP) is one…
-
Journal Article
Linear atrophoderma of Moulin: A rare case report and review of the literature
Abstract Linear atrophoderma of Moulin (LAM) is an uncommon dermatological disease characterised by linear, depressed plaques typically following Blaschko's lines. LAM generally occurs in adolescence or early adulthood and is more commonly observed in females. The aetiology of LAM is still unclear…
-
Journal Article
Evaluating the clinical efficacy of pulsed dye laser with sirolimus for treatment of capillary malformations: A systematic review
Abstract Port‐wine stains (PWS) are capillary vascular anomalies that are often treated with pulsed‐dye laser (PDL). Revascularization limits persistent clearance; however, the anti‐angiogenic effects of sirolimus (SIRO) may inhibit revascularization. This review aims to determine differences in…
-
Journal Article
Hyper‐IgE syndrome in an 11 year old female presenting with acneiform rash
Abstract Hyper‐IgE (HIES) is a rare, primary immunodeficiency characterised by eczema, recurrent staphylococcal infections, pneumonia, increased serum IgE and eosinophilia. We present the case of an 11‐year‐old girl presenting to dermatology with an acneiform facial rash and associated bacterial…