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Advanced NanoBiomed Research
Scopus
ISSN 2699-9307 · Wiley-VCH · 511 artikel di indeks
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Artikel Jurnal
A Lightweight Skin‐Adhesive Fiber Bragg Grating Sensor to Advance Minimally Invasive Healthcare Monitoring
Wearable sensors that combine high precision with conformability and skin adhesion are crucial for reliable and highly unobtrusive physiological monitoring. In this context, increasing efforts are directed toward next‐generation miniaturized self‐adhesive sensors employing different sensing…
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Implantable Drug Delivery Systems for Skeletal Muscles and Eyes
Chronic diseases require regular medication intake over a long period of time, which induce a poor adherence to treatment by patients. To overcome this limitation, new implantable drug delivery systems (IDDS) are being developed to allow optimized local drug release over a long period (often few…
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Selective Promotion of Retinal Organoid Attachment and Differentiation by Amine‐ and Hydroxyl‐Modified Surfaces
The clinical success of organoid‐based therapies depends critically on understanding and controlling how biomaterial surfaces influence organoid behavior and integration. Retinal organoids (ROs) are emerging as advanced in vitro models with potential for transplantation, yet the molecular…
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Comprehending the Membrane Properties for Emulation in Organs‐on‐a‐Chip
Membranes are fundamental to the operation of any organ. They not only act as a basal layer for cells, but also partake in transport and communication in the body. Consequently, comprehension of the role of organ‐specific membranes is just as vital to understanding the overall organ function. The…
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Surface‐Coated Inorganic Nanomaterials for Drug Delivery: Chemical Design, Biomedical Applications, and Mechanistic Insights
Enhancing the efficiency of biomedical compounds while reducing development costs and timelines remains a critical priority in pharmaceutical science. Inorganic nanomaterials (INMs) play a pivotal role in drug delivery systems (DDSs), where their properties and performance are central to practical…
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Combined Delivery of CuO Nanoparticles and HIF‐1α Inhibitor Acriflavine for Synergistic Local Treatment of Glioblastoma
Glioblastoma multiforme (GBM), the most common and highly aggressive primary malignant central nervous system tumor, has seen minimal improvement in its median survival of
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Dual Modality Semiconducting Polymer Nanoparticles for Use in Optical and Magnetic Resonance Imaging
Semiconducting polymer nanoparticles (SPNs) hold great promise as fluorescent nanoparticles with many advantageous optical and biological properties. However, their potential for optical imaging in clinical applications is currently restricted by limited tissue penetration, compared to the depth…
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Engineering Ultrasound Contrast Agents for Targeted Therapeutics: A Theranostic Approach to Drug Delivery, Gene Therapy, and Immunomodulation
Engineering of ultrasound contrast agents (UCAs) has revolutionized diagnostic imaging and therapeutic applications in medical science. These agents, comprising microbubbles (MBs) and nanobubbles (NBs), are gas‐filled structures with unique acoustic properties that not only enhance ultrasound…
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Assessing Angiogenic Properties In Vitro or In Ovo of Pre‐Crosslinked Alginate‐Dialdehyde‐Gelatin Hydrogels Incorporating Boron‐Doped Mesoporous Bioactive Glass Particles
In this study, the influence of boron (B)‐doped silicate‐based 65%SiO2–0%CaO–15%B2O3 (mol% [15B]) mesoporous bioactive glass nanoparticles (MBGN) blended in cast and 3D printed pre‐crosslinked alginate‐dialdehyde‐gelatin (ADA‐GEL) constructs is examined, both in vitro and in ovo in the chick…
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3D Hydrogel Cell Cultures and Their Biomedical Applications
In recent years, research into 3D cell cultures has grown remarkably, supporting significant advances in biomedical applications and drug development. Numerous studies have demonstrated their importance for controlling the cellular environment to better emulate natural tissue conditions and provide…
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Antibacterial Applications of Black and Violet Phosphorus‐Based Biomaterials
The accelerating emergence of antibiotic‐resistant bacteria has intensified the need for innovative antimicrobial strategies. Among promising candidates, black phosphorus (BP) and violet phosphorus (VP) nanosheets have garnered significant attention due to their unique 2D structure, large specific…
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Mannose‐Modified Cationic Liposome‐Based mRNA Therapeutics for Improved Triple‐Negative Breast Cancer Immunotherapy
Despite triple‐negative breast cancer (TNBC) is the most heterogeneous and aggressive subtype of breast cancer, immunotherapy is emerging as a promising therapy. Here, a mannose‐modified cationic liposome (cLipo)‐based mRNA therapeutics with dendritic cell (DC) targeting and high safety is…
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Redox‐Responsive Mitochondrial Delivery from Functionalized Vascular Stent Surfaces
Mitochondrial dysfunction and oxidative stress are key contributors to impaired vascular healing following stent implantation. Although drug‐eluting stents reduce restenosis, they do not promote tissue regeneration or correct cellular metabolic deficits. A redox‐responsive mitochondrial delivery…
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Micro/Nanorobot for Drug Delivery—A Review of Material Selections
The concept of utilizing micro/nanorobot (MNR) for drug delivery in vivo was raised decades ago, and numerous prototypes have been created ever since. Other than the application of delivering drugs, nanorobots are also widely researched for noninvasive surgery, cell stimulation, bioimaging…
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Zinc and Strontium‐Doped Titania Nanotube Surfaces Enhance Antibacterial Activity and Increase Osteogenic Differentiation of Mesenchymal Stem Cells
Bone is one of the critical tissues in the body as injury to it determines the quality of life for the patients. Orthopedic implants are surgical interventions which aid in maintaining the quality of life; however, bacterial infections and poor osseointegration result in implant failure which lead…
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Bioprinted Excitable Tissues with Multistimulation Systems for Promoting Function and Maturation
Bioprinted excitable tissues, including cardiac, skeletal muscle, and neural constructs, have emerged as promising platforms for modeling physiological function and disease. Alongside advances in bioprinting resolution and bioink formulation, structurally complex tissues have been fabricated with…
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Nanostructured Deep Eutectic Systems in Healthcare: From Bioactive Solvents to Intelligent Biointerfaces, Wearables, and AI‐Driven Design
The clinical translation of advanced nanomedicines and next‐generation wearables is frequently bottlenecked by material instability and interfacial incompatibility. Deep eutectic systems (DESs), historically categorized merely as green organic solvents and closely related to ionic liquids, are now…
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Biophysical Characterization and Proteomic Analysis of Small Extracellular Vesicles Derived From Different Neural Cell Lines
Small extracellular vesicles (sEVs) are nanosized membrane‐bound particles facilitating intercellular communication in the nervous system. Although previous studies investigated sEVs released from various neural cell lines, a comprehensive comparison among various immortalized neural lineages has…
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Plant Virus Immunotherapy for HPV‐Associated Oropharyngeal Squamous Cell Carcinoma
In high‐income countries, 60%–70% of oropharyngeal squamous cell carcinomas (OPSCCs) are attributable to human papillomavirus (HPV). Immunotherapy is the current second‐line treatment for advanced or metastatic cases of HPV+ OPSCC; however, drug resistance, tumor heterogeneity, and adverse events…
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Artikel Jurnal
Modified Titanium Dental Implants: The Current Progress of Soft‐Tissue Integration Methods
Dental implants are a common and effective solution for tooth loss. However, achieving consistent soft tissue integration (STI) remains a significant challenge, affecting their long‐term performance. A robust soft tissue seal around implants is essential for protecting against bacterial infection…