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BMC Genomic Data
Scopus
ISSN 2730-6844 · BMC · 418 artikel di indeks
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Artikel Jurnal
Molecular characterization of cystinosis patients: predominance of the CTNS c.829dup mutation in Center of Tunisia
Abstract Background Cystinosis is a lysosomal storage disease caused by the accumulation of intralysosomal cystine in different tissues and organs including: brain, cornea, kidneys, liver and, pancreas. This pathology is due the mutations in the CTNS gene that encode the cystinosin protein. In this…
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Artikel Jurnal
Development and validation of high-density SNP array for genomic studies in Indian yak populations
Abstract Background Yaks are multipurpose ruminants crucial for milk, meat, wool, fuel, and high-altitude transportation. Effective management of their genetic resources requires detailed knowledge of their genetic diversity, population structure, and genealogical parameters. SNP arrays offer a…
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Artikel Jurnal
De novo transcriptome assembly of hemocytes from Haliotis discus hannai following poly(I:C) stimulation
Abstract Objectives Haliotis discus hannai, a primary aquaculture species in East Asia, is highly susceptible to viral infections, such as abalone herpesvirus. To facilitate the understanding of antiviral immune mechanisms, we generated a hemocyte transcriptome dataset following stimulation with…
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Artikel Jurnal
Whole genome sequencing of 18 economically important aphid pests with photographic vouchers for taxonomic validation
Abstract Objectives Accurate molecular identification in insect monitoring programs relies on validated genomic references, yet many pest species remain underrepresented or incorrectly annotated in public databases. This Data Note provides a curated genomic resource for 18 economically important…
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Artikel Jurnal
Draft genome sequence of the plastic-degrading fungus Fusicolla acetilerea strain NIBRFGC000505922
Abstract Objectives Fusicolla acetilerea is a saprophytic fungus in the family Nectriaceae (order Hypocreales). A strain, NIBRFGC000505922, was isolated from rhizosphere soil in South Korea and showed plastic-degrading activity against polycaprolactone and polylactic acid, indicating its potential…
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Artikel Jurnal
MEFV variant spectrum and exploratory in silico stratification of uncommon variants in 611 individuals tested for suspected familial Mediterranean fever in the Eastern Black Sea region of Türkiye
Abstract Background Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory disease, caused by variants in the MEFV gene. Regional MEFV variant spectra differ across Türkiye. We characterised the MEFV variant spectrum in a single-centre series of individuals tested for…
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Artikel Jurnal
Population-resourced species-specific InDel markers for identifying putative interspecific hybrids between Populus euphratica and Populus pruinosa
Abstract Background Populus euphratica and Populus pruinosa represent core germplasm resources of desert riparian forests in northwest China. Accurate discrimination of putative interspecific hybrids between the two species is fundamental to population genetic research of desert poplars. Currently…
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Artikel Jurnal
Complete genome sequence of Streptococcus periodonticum strain CRC221 isolated from human colorectal tumor tissue
Abstract Objectives Streptococcus periodonticum is a facultative anaerobic, Gram-positive coccus originally isolated from human periodontitis lesions and implicated in colorectal cancer pathogenesis. This study aimed to comprehensively characterize the genome of strain CRC221, isolated from human…
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Artikel Jurnal
Genetic polymorphism of SNPs rs9399137 and rs4895441in HBS1L-MYB and SNP rs766432 in BCL11A among β-thalassemia Egyptian patients
Abstract Background This study aimed to evaluate the role of two genetic polymorphisms (rs9399137 and rs4895441) in the HBS1L-MYB and rs766432 of BCL11A genes as determinant HbF level and disease severity in Egyptian β-thalassemia patients. Methods Blood samples were obtained from 100 participants…
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Artikel Jurnal
Draft genome sequence and annotation of fungal pathogen Cladosporium tenuissimum SHK1100 causing postharvest sooty spot of fig fruit
Abstract Objectives Cladosporium tenuissimum, a widespread filamentous fungus belonging to the C. cladosporioides species complex, has been identified as a causal agent of sooty spot disease on postharvest fig fruits. Despite its ecological and agricultural importance, genomic resources for this…
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Artikel Jurnal
Distinct physiological and transcriptomic responses between tolerant and susceptible rapeseed (Brassica napus) germplasm to flooding stress
Abstract Waterlogging and submergence are major abiotic stresses impairing rapeseed development and hence evaluation of submergence tolerance ability is crucial for the development of tolerant lines through breeding approaches. This study investigated submergence impact on the survival rate…
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Artikel Jurnal
Bacterial community profiling of Malaysian drinking water reservoirs using metagenomic amplicon sequencing
Abstract Objectives Microbial communities in freshwater are pivotal for driving nutrient transformation, bioremediation, and maintaining the health balance of these ecosystems. However, microbial communities in freshwater ecosystems may undergo rapid shifts in composition in response to…
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Artikel Jurnal
Genome-wide identification and characterization of the RNAi gene families in Brassica rapa L. highlighting their regulatory components and underlying functions involving crop improvement
Abstract Background Brassica rapa is an oilseed crop used for vegetable oil production, with applications in both human consumption and industrial purposes. RNAi-guided gene families play crucial roles in plant growth and development by regulating gene expression in response to various pathogens…
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Artikel Jurnal
Identification of high-risk SNPs in SLC22A transporter genes: their potential role in PCOS and metformin uptake
Abstract Polycystic ovary syndrome is a prevalent, heterogeneous endocrine and metabolic disorder affecting approximately 10% of women of reproductive age, often characterized by hyperandrogenism, anovulation, and insulin resistance. Metformin, a first-line treatment for type 2 diabetes, is also…
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Artikel Jurnal
IMPDH1 is a potential immune evasion-related oncoprotein in endometrial cancer
Abstract Endometrial cancer is one of the most common gynecologic malignancies, with increasing evidence suggesting the involvement of immune-related processes rather than direct immune evasion mechanisms in its progression. However, effective immune-related biomarkers for prognostic evaluation and…
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Artikel Jurnal
Transcriptomic responses to endurance exercise training in rats
Abstract The bio-molecular changes of exercise, and how to best optimize them for improved performance, are an important human health research question. A recent study by the Molecular Transducers of Physical Activity Consortium (MoTrPAC) used a cohort of Rattus norvegicus to produce a…
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Artikel Jurnal
Complete genome sequence of Streptomyces californicus ADR1, an anti-infective, anti-biofilm and anti-oxidant producing endophyte isolated from the medicinal plant Datura metel
Abstract Objective Streptomyces californicus strain ADR1 is an endophytic actinobacterium isolated from Datura metel that produces secondary metabolites with potent antibacterial and anti-biofilm activities against WHO-listed high-priority Gram-positive pathogens. While anti-bacterial and…
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Artikel Jurnal
Divergent autoimmune genetic landscapes in diabetic and non-diabetic individuals
Abstract Background Type 2 diabetes (T2D) and autoimmune diseases are complex disorders shaped by genetic, immunological, and environmental factors. However, differences in genetic susceptibility to autoimmune disorders between diabetic and non-diabetic individuals remain poorly understood…
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Artikel Jurnal
Whole genome sequence of a superbug-Escherichia coli strain KAB-AI-497 isolated from the vagina of a 20 year old pregnant woman with premature rupture of membrane (PROM) in a resource limited setting, Kabale Regional Referral Hospital, in Uganda
Abstract Objectives The objective of the study is to sequence the whole genome of multidrug resistant E. coli strain KAB-AI-497 that causes bacterial vaginosis and implicated in premature rupture of membrane in pregnant woman. Data description The DNA of the E. coli strain KAB-AI-497 was extracted…