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BMJ Medicine
Scopus
ISSN 2754-0413 · BMJ Publishing Group · 260 artikel di indeks
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Artikel Jurnal Teks lengkap
Test accuracy of glomerular filtration rate estimation with creatinine and cystatin C in adults with moderate chronic kidney disease: prospective cohort study
Objective To study the performance of two contemporary sets of estimating equations for glomerular filtration rate, published by CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) and EKFC (European Kidney Function Consortium) that include one (creatinine or cystatin C only) and combined…
Juga tersedia di: DOAJ
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Artikel Jurnal Teks lengkap
Physical activity types, variety, and mortality: results from two prospective cohort studies
Objective To examine the associations of long term engagement in individual physical activities and physical activity variety with the risk of death.Design Prospective cohort studies.Setting Nurses' Health Study (1986-2018) and Health Professionals Follow-Up Study (1986-2020).Participants 70 725…
Juga tersedia di: DOAJ
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Artikel Jurnal
Developing a new albuminuria-free risk prediction equation for kidney failure in patients with chronic kidney disease: retrospective cohort study
Objective To develop new risk prediction equations for kidney failure in patients with chronic kidney disease who do not require data for the urine albumin to creatinine ratio.Design Retrospective cohort study.Setting Stockholm Creatinine Measurements (SCREAM) database of routinely collected…
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Artikel Jurnal
Outcome specific optimal systolic blood pressure targets in high risk patients, balancing cardiovascular benefits, renal risks, and cancer prevention: meta-analysis of randomised controlled trials
Objective To directly compare the efficacy and safety of different intensive systolic blood pressure targets (<120 or <130 mm Hg) versus usual care on cardiovascular and renal outcomes.Design Meta-analysis of randomised controlled trials.Data sources Web of Science and Medline, from inception to 20…
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Artikel Jurnal
Effects of timing and eating duration of time restricted eating on metabolic outcomes: systematic review and network meta-analysis
Objectives To evaluate the effect of overall time restricted eating on metabolic health outcomes, and to identify the optimal types of time restricted eating in terms of timing and duration of eating.Design Systematic review and network meta-analysis.Data sources PubMed, Embase, and the Cochrane…
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Artikel Jurnal
Effectiveness of non-pharmacological interventions for fatigue in long term conditions: systematic review and network meta-analysis
Objective To assess the clinical effectiveness of non-pharmacological interventions for fatigue in adults with long term medical conditions.Design Systematic review and network meta-analysis.Data sources Medline, Embase, CINAHL, APA PsycInfo, Web of Science Core Collection, and the Cochrane Central…
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Artikel Jurnal
Making clinical guidelines work for people with multiple long term conditions: analysis and recommendations from review of single condition guidelines
Objectives To evaluate how UK guidelines for individual health conditions consider coexisting multiple long term conditions and to propose improvements to guideline development processes so that guidelines appropriately account for and consider coexisting multiple long term conditions.Design…
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Artikel Jurnal
Smoking cessation for people with severe mental illness: systematic review and network meta-analysis
Objective To evaluate the comparative effectiveness and safety of pharmacological and non-pharmacological smoking cessation interventions in people with severe mental illnessDesign Systematic review and network meta-analysis.Data sources Medline, Embase, Scopus, Cochrane Central Register of…
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Artikel Jurnal
Identifying and avoiding design related biases in observational studies using the target trial framework
Observational studies are necessary to provide evidence to inform decision making in the absence of a relevant randomised trial. Although commonly criticised for potential problems due to confounding bias, design related biases in observational studies are often overlooked yet highly prevalent…
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Artikel Jurnal
Pathogenesis, screening, and diagnosis of hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy is a common heritable heart disease. The disease is genetically, anatomically, and clinically heterogeneous. Hypertrophic cardiomyopathy is inherited in an autosomal dominant pattern but has allelic heterogeneity, incomplete penetrance, and variable expressivity. Beyond…
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Artikel Jurnal
Effects of polygenic risk score communication on short term health outcomes: systematic review and meta-analysis
Objective To summarise the evidence so far from all randomised controlled trials on the efficacy of communication of polygenic risk scores in changing health outcomes.Design Systematic review and meta-analysis.Data sources Cochrane Central Register of Controlled Trials (CENTRAL) and Pubmed, from…
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Artikel Jurnal
Procalcitonin-guided decision and antibiotic treatment duration in late onset sepsis of newborns: multicentre, randomised controlled trial (ProABIS)
Objective To assess whether procalcitonin-guided decision making can safely reduce the duration of antibiotic treatment in neonatal late onset sepsis.Design Prospective multicentre, randomised open label trial.Setting 33 level 3 and level 2B neonatology departments in France.Participants Newborn…
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Artikel Jurnal
New approaches in the haemostatic management of postpartum haemorrhage
Postpartum haemorrhage is the leading cause of maternal mortality worldwide, accounting for a substantial proportion of preventable deaths, particularly in settings with limited resources. Despite its clinical significance, understanding the haemostatic changes underpinning postpartum haemorrhage…
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Artikel Jurnal
Pulmonary fibrosis: evolving therapeutic pipeline
Current treatment for pulmonary fibrosis is limited to nintedanib and pirfenidone, which slow but do not halt or reverse the progression of the disease. These treatments are widely used globally. Emerging agents, such as nerandomilast, showed positive results in phase 3 trials and was approved in…