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Jurnal

Ibrain

Scopus

ISSN 2769-2795 · Wiley-VCH · 185 artikel di indeks

  1. Artikel Jurnal

    RETRACTED: Clinical effectiveness and treatment satisfaction between two triple‐therapy regimens in treating neuropathic pain: A real‐world data

    Nithya Raju; Samyuktha Villavan; Saranya Ravi dkk.

    Ibrain, Vol. 12 No. 1 · 2026 · Inggris · DOAJ Scopus

    Abstract Triple‐therapy regimens involving Pregabalin or Gabapentin with nortriptyline and Methylcobalamin have been shown to be efficacious in treating neuropathic pain in clinical trials. This study aims to compare the clinical effectiveness and treatment satisfaction of two triple‐therapy…

  2. Artikel Jurnal

    Preclinical advances in antibodies against N‐terminal Aβ4‐x species for Alzheimer's disease and cerebral amyloid angiopathy

    Maria Luisa Valle; Donatello Arienzo

    Ibrain, Vol. 12 No. 1 · 2026 · Inggris · DOAJ Scopus

    Abstract Alzheimer's disease (AD) pathogenesis is characterized by the accumulation of amyloid beta (Aβ) deposits in the cerebral parenchyma and vasculature, a condition referred to as cerebral amyloid angiopathy (CAA). Besides the full‐length form, Aβ deposits showed a highly heterogenous…

  3. Artikel Jurnal

    Impact of early dexmedetomidine administration on short‐ and long‐term outcomes in critically traumatic brain injury patients: A retrospective study using the MIMIC‐IV database

    Yang Long; Long‐Zhen Liu; Xiao‐Xue Tan dkk.

    Ibrain, Vol. 12 No. 1 · 2026 · Inggris · DOAJ Scopus

    Abstract Traumatic brain injury (TBI) causes significant mortality. Dexmedetomidine (DEX) shows neuroprotective potential in animals, but clinical evidence remains inconsistent. We evaluated the impact of early DEX, initiated within 48 h of admission with a treatment duration of at least 4 h, on…

  4. Artikel Jurnal

    Potential neuroprotective and therapeutic agents and their mechanisms for irradiation‐induced brain injury

    Seidu A. Richard; Vivian Kapio Abem; Sagor Kumar Roy

    Ibrain, Vol. 12 No. 1 · 2026 · Inggris · DOAJ Scopus

    Abstract Cranial‐irradiation is associated with tissue damage resulting in neurocognitive impediments that adversely influence patient quality of life. Administration of radiation directly to the tumor may extend to the neighboring healthy tissues, which may induce acute to persistent oxidative…

  5. Artikel Jurnal

    Facial expression recognition for emotion perception: A comprehensive science mapping

    Hou‐Ming Kan; Li‐Ping Chen; Yu Zhang dkk.

    Ibrain, Vol. 12 No. 1 · 2026 · Inggris · DOAJ Scopus

    Abstract Facial expression recognition (FER) has emerged as a pivotal interdisciplinary research domain that bridges computer science, psychology, neuroscience, and medicine. By mapping the FER scientific knowledge graph, this study aimed to explore the technological evolution and forecast future…

  6. Artikel Jurnal

    Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

    Long Gu; Song Cao; Yonghuai Feng

    Ibrain, Vol. 12 No. 1 · 2026 · Inggris · DOAJ Scopus

    Abstract Chemotherapy‐induced peripheral neuropathy (CIPN) is a common complication in patients with malignant tumors during chemotherapy. The pathological mechanisms of CIPN remain unclear, and effective preventive and therapeutic strategies are still lacking, posing a major challenge in clinical…

  7. Artikel Jurnal

    Molecular imprinting for neurology: Materials, applications, and limitations

    Xiaohan Ma; Yingqi Ma; Claudia Marino dkk.

    Ibrain, Vol. 12 No. 1 · 2026 · Inggris · DOAJ Scopus

    Abstract Neurological disorders represent one of the most pressing challenges in contemporary medicine, requiring tools that enable early diagnosis, targeted treatment, and deeper mechanistic understanding. Conventional biological agents such as antibodies, though widely used, often face…

  8. Artikel Jurnal

    Neurobiological correlates of obsessive‐compulsive disorder (OCD): A narrative review

    Giulio Perrotta; Anna Sara Liberati

    Ibrain, Vol. 12 No. 1 · 2026 · Inggris · DOAJ Scopus

    Abstract Obsessive‐compulsive disorder (OCD) is a common and disabling, as well as underdiagnosed, neuropsychiatric condition characterized by involuntary and unwanted obsessions and/or compulsions, often accompanied by states of severe anxiety, distress and shame, as well as other comorbid…

  9. Artikel Jurnal

    Development of a predictive model for depressive symptoms in type 2 diabetes mellitus patients under community management: Based on visual function index

    Rong‐song Sun; Sheng‐xu Huo; Tian‐lin Zhang dkk.

    Ibrain, Vol. 12 No. 1 · 2026 · Inggris · DOAJ Scopus

    Abstract Visual impairment has been recognized as a potential risk factor for depressive symptoms (DS) in diabetes patients, yet the role of visual function in predicting DS remains unexplored. This study aims to develop and validate a predictive model for DS risk in type 2 diabetes mellitus (T2DM)…

  10. Artikel Jurnal

    Double gene mutations of LRSAM1 and REEP1 and a new REEP1 mutation site found in a patient with amyotrophic lateral sclerosis with subjective paresthesia: A case report

    Ji‐Yao Qin; Zun‐Lin Zhou; Yuan‐Qing Zhou dkk.

    Ibrain, Vol. 11 No. 3 · 2025 · Inggris · DOAJ Scopus

    Abstract Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by selective degeneration of upper and lower motor neurons. Although dyskinesia is the most prominent clinical manifestation of ALS, with an in‐depth understanding of disease pathogenesis and clinical…

  11. Artikel Jurnal

    Histological investigation of the interthalamic adhesion and periventricular region: Evidence for midline neural connectivity

    Nicole vanHeerden; Lané Prigge; Gerda Venter

    Ibrain, Vol. 11 No. 3 · 2025 · Inggris · DOAJ Scopus

    Abstract The interthalamic adhesion (IA), which may not be present in all humans, is a midline structure that connects the two thalami within the brain's third ventricle. A review of the known literature regarding the IA shows few histological studies and controversy regarding the organization of…

  12. Artikel Jurnal

    Study on the efficacy of compound porcine cerebroside and ganglioside injection in patients with ischemic stroke: A randomized, single‐center, open‐label, prospective study

    Ya Chen; Xia Zhang; Hai‐Qing Zhang dkk.

    Ibrain, Vol. 11 No. 3 · 2025 · Inggris · DOAJ Scopus

    Abstract Compound porcine perebroside and ganglioside injection (CPCGI) was used to treat stroke. The study was initiated because of the high incidence of low‐does CPCGI use in our area. However, no research has confirmed the effectiveness of CPCGI below the standard dose. Therefore, the aim of…

  13. Artikel Jurnal

    Diagnostic parallels between borderline and bipolar patients in psychopathology: Similarities, differences, comorbidities, neural correlates, and a new proposal for the Perrotta Border‐Bipolar Profile Diagnostic Questionnaire

    Giulio Perrotta; Simona Grilli; Stefano Eleuteri dkk.

    Ibrain, Vol. 11 No. 3 · 2025 · Inggris · DOAJ Scopus

    Abstract In psychopathology, one of the most complex challenges is offered by the diagnostic comparison between patients with borderline personality disorder and those with bipolar spectrum disorder, as some of the symptoms characterizing the two disorders overlap. This detail can mislead…

  14. Artikel Jurnal

    Research status of fetal hydrocephalus from 2003 to 2022 based on bibliometric analysis

    Qian Li; Zheyu Song; Chenyang Zhai dkk.

    Ibrain, Vol. 11 No. 3 · 2025 · Inggris · DOAJ Scopus

    Abstract Hydrocephalus is the most common and devastating condition affecting the fetus. The aim of this study was to provide a comprehensive overview of the relevant literature through bibliometric analysis. The survey covers the articles related to congenital hydrocephalus published in the Web of…

  15. Artikel Jurnal

    Median effective dosage of midazolam oral solution for preschool children in preoperative sedation

    Rui Jiang; De‐Chuan Wang; Nan Zhao dkk.

    Ibrain, Vol. 11 No. 3 · 2025 · Inggris · DOAJ Scopus

    Abstract This study aimed to detect median effective dosage (ED50) of midazolam oral solution (MOS) for preschool children in preoperative sedation. Thirty children (3–6 years old, with a body mass index (BMI) of 18–28 kg/m2, American Society of Anesthesiologists status (ASA) I‐II) scheduled for…

  16. Artikel Jurnal

    Immunomodulatory natural polysaccharide‐based nanoparticles for the treatment of neurodegenerative diseases

    Leto‐Aikaterini Tziveleka; Mariafrancesca Cascione; Paolo Pellegrino dkk.

    Ibrain, Vol. 11 No. 3 · 2025 · Inggris · DOAJ Scopus

    Abstract Polysaccharide‐based nanoparticles offer significant potential for the treatment of neurodegenerative diseases and the modulation of inflammatory responses in the central nervous system. These biopolymers, when derived from natural sources, possess inherent immunomodulatory properties…

  17. Artikel Jurnal

    Epigenetic regulation in cognitive impairment: Focus on N6‐methyladenosine modification and its potential role in perioperative neurocognitive disorders

    Ting Liu; Xiao‐Juan Yang; Lin Zhou dkk.

    Ibrain, Vol. 11 No. 3 · 2025 · Inggris · DOAJ Scopus

    Abstract N6‐methyladenosine (m6A), the most abundant internal modification in mammalian mRNA, plays a critical role in cognitive function by dynamically regulating gene expression. This narrative review examines m6A's role in cognitive processes and its potential impact on perioperative…

  18. Artikel Jurnal

    Investigating the role of SARM1 in central nervous system

    Junjie Wang; Yuhang Shi; Jinglei Tian dkk.

    Ibrain, Vol. 11 No. 3 · 2025 · Inggris · DOAJ Scopus

    Abstract Sterile‐α and Toll/interleukin 1 receptor (TIR) motif‐containing protein 1 (SARM1), a key intracellular molecule that plays numerous important biological functions in the nervous system, has attracted much attention. Recent studies have shown that SARM1 plays a key role in nerve injury…

  19. Artikel Jurnal

    Emotional recognition while watching emotional videos: Based on electroencephalography signal analysis and machine learning models

    Afshin S. Asl; Sahar Karimpour

    Ibrain, Vol. 11 No. 3 · 2025 · Inggris · DOAJ Scopus

    Abstract Depending on the impact of emotions on a person's performance and emotional disorders that can be the main cause of many mental illnesses, as well as the desire of technology to design machines that are able to change their performance according to a person's emotional states, the study of…

  20. Artikel Jurnal

    Nipocalimab‐aahu in generalised myasthenia gravis: A new Fc receptor‐targeted option for antibody‐positive patients

    Jawairya Muhammad Hussain; Anoosha Ashfaq; Azka Shahid dkk.

    Ibrain, Vol. 11 No. 4 · 2025 · Inggris · DOAJ Scopus

    Abstract Myasthenia gravis (MG) is an autoimmune disorder driven by pathogenic IgG autoantibodies, leading to muscle weakness and impaired quality of life. Conventional immunosuppressant therapies are often limited by side effects and incomplete efficacy. Nipocalimab‐aahu (N‐a), recently…