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ISSN 2770-596X · Wiley · 419 artikel di indeks
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Artikel Jurnal
Maternal and infant gut microbiome
Abstract Early‐life gut microbiome assembly is a pivotal determinant of lifelong health; however, the integrated frameworks governing this process across developmental milestones remain insufficiently defined. This review establishes a multidimensional framework by delineating the crosstalk between…
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Artikel Jurnal
The gut microbiome organ
Abstract The human gut microbiome is increasingly viewed as an active regulator of host physiology, extending beyond earlier taxonomy‐centered descriptions of a complex microbial community. Accumulating evidence supports an organ‐like conceptual framework in which the gut microbiome exhibits…
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Artikel Jurnal
A gut microbiome‐lipid axis in early pregnancy is associated with metabolic dysregulation and diabetes risk
Abstract Gestational diabetes mellitus (GDM) reflects metabolic dysregulation that becomes clinically apparent during pregnancy and shares key pathophysiological features with broader forms of diabetes. Gut microbiome‐host metabolic interactions may contribute to this process, yet their role in…
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Artikel Jurnal
Microbiome and aging: Trajectories of microbiome age across human ecosystems and their systemic effects
Abstract The “microbiome age,” a computationally derived systemic biosignature, is emerging as a pivotal framework for deciphering host aging trajectories and multi‐organ health status. Beyond merely cataloging taxonomic shifts within specific niches, this concept integrates the cumulative…
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Artikel Jurnal
Hyperoside alleviates endometrial stromal cell senescence in unexplained recurrent spontaneous abortion via DHX9‐mediated R‐loop resolution
Abstract Decidualization deficiency is a hallmark pathology of unexplained recurrent spontaneous abortion (URSA), but the undefined molecular drivers hinder the development of effective therapies. Hyperoside, a bioactive flavonoid from Hypericum perforatum, exhibits therapeutic potential against…
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Artikel Jurnal
Spatial multi‐omics unveils sphingolipid metabolic reprogramming within the retinal pathological niche
Abstract Retinal ischemia‐reperfusion (RIR) injury is a central mechanism underlying irreversible vision loss in glaucoma and other retinal diseases, yet the spatial organization of the pathogenic microenvironment remains poorly understood. Here, we constructed a high‐resolution, whole‐eye spatial…
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Artikel Jurnal
Bazi Bushen Capsule restores fertility by targeting mitochondrial health in aging endometrium
Abstract Age‐related decline in endometrial function is a major cause of fertility issues in women, but effective treatments are lacking. This study aimed to investigate the impact of Bazi Bushen Capsule (BZBS) on endometrial aging and its underlying mechanisms. Using naturally aged mice and…
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Artikel Jurnal
Wekemo Bioincloud 2026: An AI‐enabled platform for standardized multi‐omics data analyses
Abstract The rapid expansion of multi‐omics data has created an increasing demand for accessible and reproducible platforms for integrative analysis. Here, we present Wekemo Bioincloud 2026, a comprehensive upgrade of the original platform, providing 41 standardized workflows (expanded from 22)…
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Artikel Jurnal
The plant microbiome: From ecological foundations to precision microbial engineering for sustainable agriculture
Abstract Plants are best understood as evolutionary holobionts, in which the host and its associated microbiomes operate as an integrated unit to influence growth, health, and stress resilience. This comprehensive review synthesizes the most current knowledge of plant‐associated microbiomes across…