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The Lancet Regional Health - Southeast Asia
Scopus
ISSN 2772-3682 · Elsevier · 399 articles in the index
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Journal Article
Low-dose nivolumab with neoadjuvant chemotherapy and oral metronomic therapy in borderline resectable oral cavity squamous cell carcinoma: a phase II trialResearch in context
Summary: Background: Non-surgical management of oral cavity squamous cell carcinoma (OSCC) has poorer outcomes compared to surgery. In borderline resectable tumors, historical neoadjuvant chemotherapy achieves surgical conversion in only about 40%. Combining low-dose immunotherapy and oral…
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Journal Article
Burden of MASLD and liver fibrosis: evidence from Phenome India cohortResearch in context
Summary: Background: Metabolic-dysfunction-associated steatotic liver disease (MASLD) is rising globally, including in India, yet community-based data remain scarce. We address this critical knowledge gap by assessing the prevalence, distribution, and characteristics of MASLD subgroups and…
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Journal Article
Reappraising TB preventive treatment in India: programmatic and ethical implications of subclinical tuberculosis in household contacts
Summary: India's pursuit of Tuberculosis (TB) elimination is contingent on the rapid universal scale-up of TB Preventive Treatment (TPT) for household contacts. However, current strategies largely neglect the asymptomatic active (subclinical) TB stage in terms of standardized diagnosis and…
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Journal Article
Burden of subclinical coronary atherosclerosis among asymptomatic adults: the REACH–Rural India StudyResearch in context
Summary: Background: Coronary artery calcification (CAC) serves as a robust marker of subclinical atherosclerosis and an independent predictor of cardiovascular disease (CVD). Despite its clinical significance, population-based evidence on CAC prevalence and its determinants in rural India remains…
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Journal Article
Navigating through HPV stigma: an intersectional lens on community engagement for vaccine acceptance in Pakistan
Summary: Human papillomavirus (HPV) vaccination represents a significant milestone in global public health efforts to prevent cervical cancer. Yet its implementation in some countries such as Pakistan reveals complex sociocultural and geopolitical challenges. Since the staged introduction of the…
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Journal Article
Annual trends and risk factors of late presentation of HIV at 19 referral hospitals in Indonesia: findings from the INA-PROACTIVE cohortResearch in context
Summary: Background: People living with HIV (PLWH) presenting with advanced HIV have worse outcomes than those diagnosed earlier. The proportion of PLWH in Indonesia who are late presenters is unknown but likely high. Identifying factors associated with late presentation is key to earlier diagnosis…
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Journal Article
Invasive mould infections of the central nervous system in the Indian population: a cohort study (2004–2025)Research in context
Summary: Background: Central nervous system (CNS) invasive mould infection (IMI) is a rare but life-threatening condition. Limited large-scale studies hinder the understanding of its clinical characteristics and optimal management strategies. Methods: This was a cohort study. We reviewed confirmed…
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Journal Article
Performance and utility of contact tracing for COVID-19 in the WHO South-East Asia Region: implications for future pandemic preparedness
Summary: Contact tracing was widely implemented during the COVID-19 pandemic, but its real-world performance and utility for decision-making remain poorly understood. A qualitative study was conducted to appraise the performance and utility of contact tracing for COVID-19 in the WHO South-East Asia…
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Journal Article
Long-term sequelae and functional outcomes in the largest cohort of Nipah virus survivors in BangladeshResearch in context
Summary: Background: Since 2001, Bangladesh has experienced recurrent outbreaks of Nipah virus (NiV) infection. While acute-phase manifestations are well documented, long-term clinical and functional sequelae poorly characterized. Methods: We conducted a cross-sectional assessment of 52 adult NiV…
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Journal Article
Sexual harassment in India's medical education: need for accountability
Summary: Sexual harassment in medical education is a global, structurally embedded problem driven by rigid hierarchical cultures, with trainees disproportionately exposed to higher levels of harassment. Policy recommendations reframe harassment as a public health issue, and call for trauma-informed…
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Journal Article
Kyasanur Forest Disease: feasible strategies for vaccine development and evaluation
Summary: Kyasanur Forest Disease (KFD) is a tick-borne zoonotic infection endemic to certain parts of India, with expanding geographic distribution and recurrent focal outbreaks among forest-dependent populations in Western Ghats. The discontinuation of the formalin-inactivated KFD vaccine in 2022…
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Journal Article
Immunogenicity and safety of high-dose versus double-dose quadrivalent inactivated influenza vaccine in adult kidney transplant recipients: a randomized controlled trial (2023)
Summary: Background: Solid organ transplant (SOT) recipients are at increased risk of influenza-related complications and often exhibit suboptimal vaccine responses. While both high-dose (HD) and double-dose (DD) quadrivalent inactivated influenza vaccines (QIIV) aim to enhance immunogenicity…
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Journal Article
Soil-transmitted helminthiasis prevalence and infection intensity among school-going children in Timor-Leste after the prolonged interruption of deworming: a cross-sectional survey (2025)
Summary: Background: Timor-Leste reduced soil-transmitted helminth (STH) prevalence from 29% to 18% by 2020 through mass drug administration (MDA) in 2015–2019. School-based deworming was interrupted for nearly four years during the COVID-19 pandemic and resumed in 2022 in 3 municipalities and…
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Journal Article
Clinical characteristics of nontuberculous mycobacterial infections among people with presumptive tuberculosis in India: a multicenter study (2021–2025)Research in context
Summary: Background: Disease caused by nontuberculous mycobacteria (NTM) is often misdiagnosed as tuberculosis (TB) in India. Comprehensive studies on NTM are lacking, therefore, the present study aimed to describe clinical features, underlying conditions, species distribution, and treatment…
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Journal Article
Scale of unmet solid organ transplantation need in India: a projection for organ transplant need by 2040Research in context
Summary: Background: Solid organ transplantation (SOT) is the definitive therapy for end-stage organ failure. Despite the world's third-highest transplant volume, India has no systematic assessment of unmet transplant need across organs. Methods: We modelled 1) Global Burden of Disease 2021…
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Journal Article
Stillbirths at 22- and 28-weeks’ gestation or longer for the states in India: findings from the Global Burden of Disease Study 2023Research in context
Summary: Background: The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD), for the first time, estimated stillbirth rate (SBR) by the WHO ICD-11 definition (≥22 weeks' gestation) for 204 countries, highlighting the extent of underestimation in stillbirth burden as compared with…
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Journal Article
Self-management education and support for type 2 diabetes in Thailand: a cluster randomized trial (2019–2021)Research in context
Summary: Background: Diabetes self-management education and support (DSMES) improves glycemia via improved care coordination and self-management behaviors driven by educational programs tailored to individual needs, but scalable models for its delivery in low- and middle-income countries are…