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Editorial Board

JACC: Asia, Vol. 6 No. 3 · 2026 · Inggris · DOAJ Scopus

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JACC: Asia, Vol. 6 No. 3 · 2026 · Inggris · DOAJ Scopus

Asia at the Epicenter of the Global Cardiometabolic Shift

Shaun Khanna, MBBS, MMed; Gary C.H. Gan, MBBS, PhD; Andrew P. Sindone, BMed, MD dkk.

JACC: Asia, Vol. 6 No. 3 · 2026 · Inggris · DOAJ Scopus

Cardiometabolic disease has become the dominant noncommunicable health challenge of the 21st century, with its burden increasingly centered in Asia. Rising obesity, type 2 diabetes mellitus, hypertension, and dyslipidemia now account for more than one-third of cardiovascular mortality. This…

A Modern Valve, An Old Complication

Matteo Sturla, MD; Pier Pasquale Leone, MD; Azeem Latib, MD

JACC: Asia, Vol. 6 No. 3 · 2026 · Inggris · DOAJ Scopus

TAVR for Pure Aortic Regurgitation

Yu Mao, MD; Mengen Zhai, MD; Ping Jin, MD dkk.

JACC: Asia, Vol. 6 No. 3 · 2026 · Inggris · DOAJ Scopus

Transcarotid Access for TAVR

Robert Milford Tungate, MD; Antonio H. Frangieh, MD, MPH

JACC: Asia, Vol. 6 No. 3 · 2026 · Inggris · DOAJ Scopus

Treatment Paradigm Shifts in Pulmonary Arterial Hypertension

Wen Wen, MD; Yunshan Cao, MD, PhD

JACC: Asia, Vol. 6 No. 3 · 2026 · Inggris · DOAJ Scopus

Cholesterol-Inflammation Fusion Hypothesis in Atherosclerosis

Rui-Xiang Zeng, MD; Sha Li, MD; Jian-Jun Li, MD, PhD

JACC: Asia, Vol. 6 No. 3 · 2026 · Inggris · DOAJ Scopus

Atherosclerosis (AS) remains the leading cause of cardiovascular morbidity and mortality worldwide despite advances in multidimensional prevention and treatment. We propose a novel cholesterol-inflammation fusion hypothesis, a unifying framework that conceptualizes AS as a self-perpetuating disease…

Atrial Fibrillation Management by Pulmonary Vein Isolation in Patients With Complex Congenital Heart Disease

Masayuki Sakai, MD; Satoshi Higuchi, MD, PhD; Yuko Matsui, MD dkk.

JACC: Asia, Vol. 6 No. 3 · 2026 · Inggris · DOAJ Scopus

Precision Medicine for Atrial Fibrillation Recurrence in East Asia

Takeshi Aiba, MD, PhD

JACC: Asia, Vol. 6 No. 3 · 2026 · Inggris · DOAJ Scopus

Hemolysis After TAVR Using the Fifth-Generation Balloon-Expandable Valve

Shinichi Kurashima, MD; Atsushi Okada, MD, PhD; Yuki Irie, MD dkk.

JACC: Asia, Vol. 6 No. 3 · 2026 · Inggris · DOAJ Scopus

Background: Hemolytic anemia (HA) following transcatheter aortic valve replacement (TAVR) using the fifth-generation SAPIEN 3 Ultra RESILIA (S3UR) valves has been reported nationwide since its approval in Japan. Objectives: The purpose of this study was to investigate the incidence and predictors…

Drugs Don't Work in Patients Who Don't Take Them

Min Soo Cho, MD, PhD

JACC: Asia, Vol. 6 No. 3 · 2026 · Inggris · DOAJ Scopus

Understanding and Mitigating Bleeding Risks in Extracorporeal Cardiopulmonary Resuscitation

Guangju Zhou, MD; Qin Lu, MD, PhD

JACC: Asia, Vol. 6 No. 3 · 2026 · Inggris · DOAJ Scopus

Medication Adherence and Antithrombotic Therapy Outcomes

Naoki Chiba, MD; Takashi Noda, MD, PhD; Kotaro Nochioka, MD, PhD dkk.

JACC: Asia, Vol. 6 No. 3 · 2026 · Inggris · DOAJ Scopus

Background: The AFIRE (Atrial Fibrillation and Ischemic Events With Rivaroxaban in Patients With Stable Coronary Artery Disease) trial demonstrated that rivaroxaban monotherapy has noninferior efficacy and superior safety compared with combination therapy (rivaroxaban plus a single antiplatelet) in…

Phase 3, Open-Label Multicenter Study of Sotatercept in Japanese Participants With Pulmonary Arterial Hypertension

Hiromi Matsubara, MD, PhD; Nobuhiro Tanabe, MD, PhD; Takeshi Ogo, MD, PhD dkk.

JACC: Asia, Vol. 6 No. 3 · 2026 · Inggris · DOAJ Scopus

Background: Sotatercept is a first-in-class activin signaling inhibitor, developed for the treatment of pulmonary arterial hypertension (PAH). Objectives: This open-label single-arm, multicenter, phase 3 study was initiated to evaluate the efficacy and safety of sotatercept in Japanese participants…

Predictors of Bleeding Complications After Extracorporeal Cardiopulmonary Resuscitation

Madoka Sano, MD; Toshiaki Toyota, MD, PhD; Yoshinori Matsuoka, MD, PhD dkk.

JACC: Asia, Vol. 6 No. 3 · 2026 · Inggris · DOAJ Scopus

Background: Extracorporeal cardiopulmonary resuscitation (ECPR), an emerging resuscitative therapy following refractory cardiac arrests, is associated with hemorrhagic complications that potentially affect patient outcomes. Objectives: This study evaluated the risks and predictors of hemorrhagic…

Diabetes and ALDH2 Gene Polymorphism on Post-Ablation Atrial Fibrillation Recurrence

Junyan Jin, PhD; Ningjing Qian, MD; Ying Gao, PhD dkk.

JACC: Asia, Vol. 6 No. 3 · 2026 · Inggris · DOAJ Scopus

Background: Type 2 diabetes mellitus (T2DM) and mitochondrial aldehyde dehydrogenase 2 (ALDH2) gene polymorphism exhibit significant associations with atrial fibrillation (AF) prevalence. Objectives: This study aimed to evaluate the combined risk of T2DM and ALDH2 gene polymorphism in AF recurrence…

Midterm Outcomes of a Novel Physician-Modified Inner-Branch Iliac Branch Device for Internal Iliac Artery Reconstruction

Mingwei Wu, MD, PhD; Li Zhang, MD, PhD; Shichao Liang, MD, PhD dkk.

JACC: Asia, Vol. 6 No. 3 · 2026 · Inggris · DOAJ Scopus

The anatomical eligibility of the Iliac Branch Device (IBD) remains limited, primarily caused by the additional common iliac artery (CIA) space occupied by its outer branch. Given that East Asian populations typically have smaller CIA diameters and lengths than Western populations, the anatomical…

Suitability for Transcarotid Transcatheter Aortic Valve Replacement in the Japanese Population

Masaki Nakashima, MD; Natsuko Satomi, MD; Daishi Tazawa, MD dkk.

JACC: Asia, Vol. 6 No. 3 · 2026 · Inggris · DOAJ Scopus

Background: Transcarotid (TC) transcatheter aortic valve replacement (TAVR) has shown favorable outcomes in selected Western populations; however, data on its suitability in patients undergoing TAVR remain scarce. Objectives: The purpose of this study was to investigate the anatomical…

Enhancing PCI Outcomes With Postprocedural Murray Law-Based Quantitative Flow Ratio

Kosei Terada, MD, PhD; Kazumasa Ikeda, MD; Yasuhiro Honda, MD

JACC: Asia, Vol. 5 No. 1 · 2025 · Inggris · DOAJ Scopus