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Annals of Rheumatology and Autoimmunity
ISSN 2773-0522 · Wolters Kluwer Medknow Publications · 95 artikel di indeks
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Misleading Neurological Presentation of Undiagnosed Marfan Syndrome: A Case Report
Marfan syndrome (MFS) is an autosomal dominant disorder characterized by multisystem connective tissue involvement, affecting the cardiovascular, skeletal, and ocular systems. Here, we report the case of a 54-year-old male with diabetes and hypertension who presented with dizziness and left-sided…
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Medical Case Report: Autosomal Recessive Progressive Pseudorheumatoid Dysplasia
Progressive pseudorheumatoid dysplasia (PPRD) is a rare genetic skeletal disorder characterized by the progressive degeneration of articular cartilage, resulting in joint pain, stiffness, and deformities. Due to its rarity, the majority of available knowledge comes from isolated case reports, with…
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The Correlation of MRI Findings in Newly Diagnosed Axial Spondyloarthritis with the Practiced Subjective Patient-Reported Disease Activity Scores
Objective: The objective of the study was to evaluate the correlation between magnetic resonance imaging (MRI) findings and patient-reported disease activity scores – bath ankylosing spondylitis disease activity index (BASDAI), ankylosing spondylitis disease activity score (ASDAS) based on…
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Intracranial Arachnoid Cyst in a Patient with Axial Spondyloarthritis Following Anti-TNF-α Therapy: A Case Report
Coexistence of axial spondyloarthritis (axSpA) and arachnoid cysts, especially in the intracranial region, is rare and infrequently described in the literature. This report presents the case of a 39-year-old male patient with axSpA who developed new-onset neurological symptoms, including left arm…
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Musculoskeletal Manifestations in Pediatric Inflammatory Bowel Disease Patients in a Single-Tertiary Center
Background: Inflammatory bowel disease (IBD) is a chronic gastrointestinal disorder with extra-intestinal manifestations (EIMs), including joint involvement. However, the relationship between joint symptoms and the natural progression of IBD in the pediatric population remains unclear. Objective…
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Renal Involvement in Rheumatological Disorders: Prevalence and Determinants from a Tertiary Care Center in India
Background: Renal involvement is a common but often overlooked complication of rheumatological disorders, contributing to significant morbidity. Aim: This study aimed to determine the prevalence and spectrum of renal involvement in rheumatological diseases and identify associated clinical and…
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Refractory Lupus Panniculitis Successfully Treated with Anifrolumab: A Case Report
Lupus panniculitis is an uncommon type of chronic cutaneous lupus erythematosus (CCLE). In cases refractory to traditional immunosuppressants, management is challenging. Anifrolumab has shown effectiveness in systemic lupus erythematosus (SLE); however, data on isolated cutaneous lupus are limited…
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Clinical Significance of Positive Antinuclear Antibody Tests in Adults at a Tertiary Care Hospital
Introduction: Antinuclear antibody (ANA) positivity is not limited to autoimmune pathology; it can be present in a variety of non-autoimmune illnesses as well as healthy individuals. The purpose of this study is to elucidate the clinical significance of positive ANA in adults in a hospital setting…
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The Spectrum of Rheumatic Diseases and Associated Comorbidities among Patients Visiting the Rheumatology Clinic in Taif, Saudi Arabia: A Single-center Experience
Background: Autoimmune rheumatic diseases (AIRDs) represent emerging diseases in modern life with a great burden and complications. Objectives: To make a descriptive analysis for a sample of patients came to visit rheumatology clinic in Taif, Saudi Arabia to know the spectrum of rheumatic diseases…
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Beta-Thalassemia Major with Secondary Hemochromatosis and Concomitant Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse clinical manifestations and multiorgan involvement. Beta-thalassemia (β-thalassemia) major is a hereditary hemoglobinopathy characterized by the absence of beta-globin chain synthesis, ineffective erythropoiesis, and…
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Procalcitonin Levels in Patients with Juvenile Idiopathic Inflammatory Myopathies
Background: Patients with juvenile idiopathic inflammatory myopathies (JIIMs) are at an increased risk of infection due to immunosuppression. Serum procalcitonin (PCT) is a biomarker for diagnosing bacterial infections. While no substantial studies have examined PCT in JIIM, it is slightly elevated…
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A Fine Line between Benign and Autoimmune: The Kikuchi–Fujimoto–Lupus Diagnostic Trap—A Case Report
The diagnostic overlap between autoimmune and inflammatory disorders remains a persistent challenge, particularly when rare conditions mimic systemic diseases with established diagnostic criteria. Kikuchi–Fujimoto disease (KFD), a rare form of necrotizing histiocytic lymphadenitis, is a benign and…
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Knowledge and Management Practices of Pediatric Orthopedic Surgeons Regarding Progressive Pseudorheumatoid Dysplasia: A Cross-Sectional Study
Background: Progressive pseudorheumatoid dysplasia (PPD) is a rare genetic skeletal disorder that is frequently missed or misdiagnosed due to overlapping features with juvenile idiopathic arthritis. This study aimed to assess the knowledge, diagnostic capabilities, and management practices of Saudi…
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Clinical Characteristics, Management, and Outcomes of Patients with MDA5-associated Rapidly Progressive Interstitial Lung Disease: A Single-center Observational Study from Qatar
Background: Melanoma differentiation-associated protein 5 (MDA5) dermatomyositis (DM; MDA5-DM) is a distinct subtype of DM often complicated by rapidly progressive interstitial lung disease (RP-ILD) and high mortality. Although the prevalence of anti-MDA5 antibodies among idiopathic inflammatory…
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Macrophage Activation Syndrome and Acute Kidney Injury in Adult-Onset Still’s Disease Despite IL-6 Inhibition: Managed with Intravenous Anakinra
This report describes a rare case of adult-onset Still’s disease (AOSD) complicated by macrophage activation syndrome (MAS) and acute kidney injury (AKI), despite ongoing interleukin-6 (IL-6) inhibition. The case highlights the diagnostic challenges of MAS in patients receiving IL-6 blockade…
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Natural Products in Rheumatoid Arthritis: Mechanistic Insights and Therapeutic Potential
Rheumatoid arthritis (RA) is a long-lasting autoimmune condition that leads to painful joint inflammation, an increase in synovial tissue, and the breakdown of cartilage, all of which can greatly diminish a person’s quality of life. While traditional treatments like disease-modifying antirheumatic…
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Autoimmune Encephalitis: The Rheumatologist’s Perspective
Background: Acute encephalitis is a condition where the brain is inflamed, and it has a wide range of potential causes. Even though autoimmune encephalitis (AE) is a rare disease, the incidence is increasing over the years. This may reflect rising awareness and improvement in diagnostic advances…
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The Uric Acid Dilemma: A Nutritional Odyssey
Gout prevalence continues to rise worldwide, with an estimated 53.9 million cases in 2019, representing a 22% increase in age-standardized prevalence compared to 1990. Although urate-lowering pharmacotherapy remains the cornerstone of management, dietary factors constitute a critical modifiable…