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Anti-Aging Eastern Europe
ISSN 2786-6521 · Edeme Resort Medical & Spa · 156 articles in the index
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Journal Article
CAN HEALTHY LONGEVITY BE ACHIEVED DESPITE ACCELERATED BIOLOGICAL AGING IN INFLAMMATORY RHEUMATIC DISEASES? A GEROSCIENCE-BASED HYPOTHESIS
Inflammatory rheumatic diseases (IRDs) are increasingly recognized as disorders of accelerated biological aging, characterized by chronic inflammation, immunosenescence, cellular senescence, and progressive loss of physiological resilience. These processes contribute to frailty, multimorbidity…
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Journal Article
IGG4-Related Disease as a Clinical Model of Immune Aging: Linking Immunosenescence and Fibroinflammation
Immunoglobulin G4-related disease (IgG4-RD) is a chronic inflammatory and immune-mediated disorder characterized by progressive fibrosis, primarily affecting glandular tissue. While recognition of the disease has increased significantly in recent years, its underlying immunopathology does not fully…
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Journal Article
BRACHIAL PLEXOPATHY SECONDARY TO CHRONIC UPPER EXTREMITY LYMPHEDEMA FOLLOWING BREAST CANCER TREATMENT: A CASE REPORT
A 75-year-old woman with a history of left breast cancer treated with total mastectomy, axillary lymph node dissection, chemotherapy, and radiotherapy developed progressive left upper extremity lymphedema one year after radiotherapy. She later presented with sudden onset numbness and profound…
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Journal Article
DIGITAL PHENOTYPING AND ARTIFICIAL INTELLIGENCE FOR PREDICTING MUSCULOSKELETAL REHABILITATION OUTCOMES
Rehabilitation outcomes in musculoskeletal disorders vary considerably among patients with similar diagnoses and baseline characteristics. Conventional prognostic assessment relies mainly on measurements obtained during isolated clinical encounters and may therefore overlook fluctuations in…
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Journal Article
PHYSICAL ACTIVITY TO PREVENT MULTIMORBIDITY
PHYSICAL ACTIVITY TO PREVENT MULTIMORBIDITY
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Journal Article
THE ROLE OF THE GUT MICROBIOME IN THE RISK OF CARDIOVASCULAR DISEASE: FROM DYSBIOSIS TO ATHEROTHROMBOSIS
This review article analyses current understanding of the role of the gut microbiome in the development of cardiovascular diseases. The gut microbiome is considered a complex environmental system involved in the regulation of metabolic, immune and inflammatory pathways that are directly relevant to…
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Journal Article
HYPERPIGMENTATION IN PREGNANCY: PATHOPHYSIOLOGY, CLINICAL FEATURES, AND CONTEMPORARY MANAGEMENT STRATEGIES
Pregnancy-associated hyperpigmentation represents one of the most frequent dermatological conditions observed during gestation, with melasma being its most clinically significant form. Its pathogenesis is multifactorial and involves complex interactions between hormonal fluctuations, particularly…
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Journal Article
MEN’S HEALTH IN AUTOIMMUNE RHEUMATIC DISEASES: AGING, IMMUNITY, AND HORMONAL INTERACTIONS
Autoimmune rheumatic diseases (ARDs), such as rheumatoid arthritis, systemic lupus erythematosus, and ankylosing spondylitis, are chronic inflammatory conditions that demonstrate significant sex differences in prevalence, clinical presentation, disease expression, and long-term outcomes. While…
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Journal Article
SEXUAL HEALTH AND INFECTION RISK DURING THE PERIMENOPAUSAL AND POSTMENOPAUSAL TRANSITION
Sexual health in perimenopausal and postmenopausal women is shaped by complex interactions between hormonal fluctuations, physical changes, and psychosocial factors. Declines in estrogen and other sex hormones contribute to reduced sexual desire and arousal, while urogenital discomfort, fatigue…
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Journal Article
BOTULINUM TOXIN FOR THE TREATMENT OF MICROSTOMIA IN SYSTEMIC SCLEROSIS: A LITERATURE REVIEW
Systemic sclerosis (SSc) is a multisystem autoimmune disease characterized by brosis and vasculopathy, commonly leading to microstomia – an abnormally reduced oral aperture that impairs speech, nutrition, and quality of life. Conventional options for managing SSc-related microstomia – for example…
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Journal Article
UNDER-RECOGNITION OF MENOPAUSE-RELATED SYMPTOMS AND TREATMENT PATTERNS: A CROSS-SECTIONAL SURVEY OF WOMEN
Background: Women in perimenopause and menopause often have physical and psychological symptoms, which are frequently overlooked or misattributed. Although treatments like hormone replacement therapy (HRT) exist and management approaches vary, antidepressants are frequently prescribed. Objective…
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Journal Article
CLINICAL RELEVANCE OF SARCOPENIA: ETIOLOGY, PREVALENCE, PATHOPHYSIOLOGY, ASSESSMENT
The rapid global aging of the population has heightened the clinical importance of sarcopenia, an interdisciplinary condition characterized by the progressive and widespread decline in skeletal muscle mass, strength, and function. Now formally recognized as a distinct muscle disease, sarcopenia is…
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Journal Article
INDIVIDUALIZED TREATMENT OF POLYCYSTIC OVARY SYNDROME: A MANIFESTATION-GUIDED PRACTICAL APPROACH
Polycystic ovary syndrome (PCOS) is a highly heterogeneous endocrine-metabolic disorder with reproductive, metabolic, dermatologic, and psychological manifestations that vary substantially across affected women. This marked phenotypic diversity limits the usefulness of a uniform treatment model and…
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Journal Article
REHABILITATION-BASED DEPRESCRIBING OF MULTIPLE CENTRAL NERVOUS SYSTEM-ACTIVE MEDICATIONS IN CHRONIC PAIN: A CASE REPORT
Polypharmacy involving central nervous system (CNS)-active medications is common in patients with chronic pain and may contribute to adverse effects, functional decline, and prescribing cascades. Rehabilitation-based deprescribing addresses pain through non-pharmacological strategies. Herein, we…
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Journal Article
GERIATRIC PHOTOGRAPHY IN CLINICAL PRACTICE
GERIATRIC PHOTOGRAPHY IN CLINICAL PRACTICE
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Journal Article
LATE-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS: CLINICAL FEATURES, COMORBIDITIES, AND MORTALITY IN A SINGLE-CENTER COHORT
Background: Late-onset systemic lupus erythematosus (Lo-SLE) is a rare subgroup of SLE characterized by disease onset at ≥50 years of age and a distinct clinical phenotype. This study aims to evaluate the clinical and laboratory characteristics, comorbidities, and mortality rates of Lo-SLE patients…
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Journal Article
LIGHTING FOR HEALTHY LONGEVITY AT HOME: A NARRATIVE REVIEW
Modern humans spend most of their lives indoors; as a result, the domestic light environment has become a pervasive determinant of physiology and well-being. Light entrains circadian rhythms via intrinsically photosensitive retinal ganglion cells (ipRGCs), modulates endocrine activity such as…
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Journal Article
TOPHACEOUS GOUT MANAGEMENT IN A 78-YEAR-OLD FEMALE PATIENT: A CASE REPORT
Gout is a prevalent form of inflammatory arthritis that primarily affects the older population. Treatment of gout in the older is more complex and difficult than in younger patients. The therapeutic agents remain consistent; nevertheless, effective treatment is hindered by the increase of…
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Journal Article
IDIOPATHIC COMPLEX REGIONAL PAIN SYNDROME (CRPS): A CASE SERIES
Complex regional pain syndrome (CRPS) is a rare disorder that presents with motor, sensory, sudomotor, and vasomotor symptoms and favors females in a 2:1-4:1 ratio. This syndrome can be idiopathic without identifiable nerve damage, classified as CRPS I, or occur following trauma or surgery with…
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Journal Article
THE AGE FACTOR IN NAILFOLD VIDEOCAPILLAROSCOPY IN SYSTEMIC SCLEROSIS: A HYPOTHESIS
Systemic sclerosis (SSc) is characterized by immune-mediated microangiopathy and fibrosis, and nailfold videocapillaroscopy (NVC) is central to diagnosis, risk stratification, and follow-up. Capillary density increases until approximately the age of 10, after which the trend diminishes in older…