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Scopus
ISSN 2790-6760 · KeAi Communications Co., Ltd. · 98 artikel di indeks
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Artikel Jurnal
Nanotechnology-enhanced liquid biopsies and genomic biomarkers: Emerging landscapes for early cancer detection
Early detection of cancer is essential for improving patient survival, yet current diagnostic methods such as imaging and tissue biopsy are limited by invasiveness, sampling bias and low sensitivity at early disease stages. Liquid biopsy has emerged as a minimally invasive approach that enables…
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Artikel Jurnal
Next-generation injectable hydrogels: Advanced crosslinking strategies, multi-stimuli responsiveness, and translational advances for precision regenerative medicine
Injectable hydrogels represent a transformative platform in biomaterials, enabling minimally invasive delivery and precise therapeutic localization with biomimetic structural and functional properties. Recent innovations in chemistry and crosslinking ranging from photopolymerization, click…
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Artikel Jurnal
Curcumin poly D-L lactide nanoparticles demonstrate superior antiplasmodial Efficacy and multi-target binding compared with dihydroartemisinin: Integrative in vivo and in silico analyses
Background: The urgent rise of drug-resistant malaria underscores the need for innovative antimalarial agents with multi-targeting capabilities. Curcumin, a polyphenolic compound derived from turmeric, is known for its extensive pharmacological properties; however, its low bioavailability hinders…
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Artikel Jurnal
Synergistic activity of photoactivated curcumin-derived nanocomplexes in combination with antibiotics against planktonic and biofilm bacterial cells
Background: Alternative antimicrobial strategies such as antimicrobial photodynamic therapy (aPDT) and curcumin-derived nanocomplexes were assessed in this study against biofilm cells of Gram-positive and Gram-negative clinical isolates. Methods: Curcumin-derived nanocomplexes (curcumin-chitosan…
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Artikel Jurnal
The anticancer, antioxidant, and antimicrobial properties of zinc oxide nanoparticles: A comprehensive review
This review provides a comprehensive analysis of Zinc Oxide Nanoparticles (ZnO NPs) in biomedical applications, focusing on their anticancer, antioxidant, and antimicrobial properties. ZnO NPs, distinguished by their unique physicochemical attributes, are increasingly recognized in nanomedicine for…
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Artikel Jurnal
Integration of graphene quantum dots with 3D scaffolds for precision medicine and regenerative applications
Integrated onto three-dimensional (3D) scaffolds, graphene quantum dots (GQDs) present a novel method for tissue creation and precision drug delivery. Among its special characteristics are photoluminescence, biocompatibility, and a large surface area fit for functionalizing. Targeting drug…
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Artikel Jurnal
Tumor microenvironment-responsive nanoplatforms for enhanced cancer immunotherapy: Advances and synergistic strategies
Despite remarkable advancements in cancer immunotherapy, its clinical efficacy remains constrained by challenges including insufficient tumor accumulation of immunotherapeutics, limited patient response rates, and immune-related adverse events. Tumor microenvironment (TME)-responsive nanoplatforms…
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Artikel Jurnal
Nanocarrier-based insulin delivery: A leap towards a needle-free future
The burden of diabetes mellitus continues to escalate globally, demanding innovative and patient-centric therapeutic alternatives to conventional insulin injections. Nanocarrier-based drug delivery systems offer transformative potential in diabetes management by enabling needle-free, targeted, and…
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Artikel Jurnal
“Green” gas-generation strategy to combine cancer phototherapy for remarkably enhanced efficacy
Phototherapy, which mainly includes photodynamic therapy (PDT) and photothermal therapy (PTT), has made considerable progress in the field of cancer treatment by generating reactive oxygen species or hyperthermia under photorespiration to selectively damage cancer cells. However, PDT or PTT…
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Artikel Jurnal
In-silico strategies in nano-drug design: Bridging nanomaterials and pharmacological applications
Rapid advancements in nanotechnology have transformed drug design and delivery systems, allowing for precise and efficient therapeutic interventions. This review examines the transformative role of in-silico approaches in nano-drug design, focusing on their ability to predict, optimize, and refine…
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Artikel Jurnal
Mitigating oxidative stress toxicities of environmental pollutants by antioxidant nanoformulations
Oxidative stress arising from reactive oxygen and nitrogen species (RONS) imposes a severe threat to living organisms by causing extensive cellular and subcellular damage. Environmental pollutants (e.g., xenoestrogens, pesticides, heavy metals, and polycyclic aromatic hydrocarbons) further amplify…
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Artikel Jurnal
Plant-based nanotherapeutics: A new frontier in disease management and prevention
Nanotechnology has emerged as a transformative force in the field of medicine, offering innovative solutions for the diagnosis, treatment, and prevention of diseases. Among the myriad sources of nanomaterials, plant-based nanotherapeutics stand out due to their biocompatibility, eco-friendliness…
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Artikel Jurnal
Redox-sensitive camptothecin prodrug: A promising drug delivery strategy with ultrahigh drug loading and tunable drug release
Small molecular drugs play a critical role in cancer therapy but face challenges like poor solubility, severe side effects, and inefficient delivery. Polymeric micellar-based drug delivery systems show promise but struggle with low drug loading, instability, and premature drug release partly due to…
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Artikel Jurnal
Selenium, silver, and gold nanoparticles: Emerging strategies for hepatic oxidative stress and inflammation reduction
Liver failure, primarily driven by oxidative stress and inflammation, remains a significant clinical challenge. Conventional hepatoprotective strategies often fail to provide effective long-term protection, necessitating the exploration of novel therapeutic approaches. This review focuses on the…
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Artikel Jurnal
Liposome-encapsulated therapies: Precision medicine for inflammatory lung disorders
Liposomes have emerged as the preferred choice over other nanocomposites for transporting a wide range of hydrophobic and hydrophilic compounds with therapeutic potential. This is primarily due to their exceptional degradation ability, compatibility within biological systems, and minimal…
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Artikel Jurnal
Liquid biopsy based on EV biomarkers: A new frontier for early diagnosis and prognosis assessment of cancer at ESMO 2024
Extracellular vesicles (EVs) are emerging as powerful biomarkers in liquid biopsy, offering insights into early cancer diagnosis, precision treatment, and prognosis evaluation. EVs, including microvesicles, exosomes, and apoptotic bodies, carry molecular cargo that reflects the physiological or…
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Artikel Jurnal
Nanoparticles for drug delivery: Insight into in vitro and in vivo drug release from nanomedicines
Nanotechnology enables the achievement of the desired outcomes of nano-formulations, and the mode of drug delivery from the nanoparticles can significantly impact the efficacy of the embedded drug. This article reviews the various types of nanoparticles, methods of evaluating the drug release, in…