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Frontiers in Nephrology
Scopus
ISSN 2813-0626 · Frontiers Media S.A. · 297 artikel di indeks
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Artikel Jurnal
Beyond the resistive index: value of color-coded duplex sonography parameters in kidney transplantation
Sonography is a key method in examining kidney transplants. Recent reports on the limited diagnostic value of an elevated resistive index (RI) in detecting rejection have cast doubt on the overall utility of color-coded duplex sonography (CCDS). This study evaluated additional CCDS parameters –…
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Artikel Jurnal
The potential of neutrophil gelatinase-associated lipocalin in management of acute kidney injury and peritoneal dialysis-related peritonitis: a narrative review
Neutrophil gelatinase-associated lipocalin (NGAL) is a biomarker extensively studied in multiple diseases. While its application in chronic kidney disease (CKD) and kidney transplant patients is relatively limited, NGAL has shown significant promise in the early detection and diagnosis of acute…
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Artikel Jurnal
New insights into contrast-associated acute kidney injury: the key role of endothelial dysfunction
BackgroundContrast-Associated Acute Kidney Injury (CA-AKI) is a major cause of acute kidney injury in hospitalized patients, which is triggered by the administration of iodinated contrast agents during computed tomography scans and angiographic procedures. It significantly elevates cardiovascular…
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Artikel Jurnal
The border between progenitor cell recruitment and nephron shaping in the fetal human kidney during late gestation: a basic but understudied region
IntroductionThe last 3 months of pregnancy are formative for the development of the fetal human kidney. Clinical experience with preterm and low birth weight infants indicates particular vulnerability during this period, as different noxae can terminate the development of new nephrons. This leads…
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Artikel Jurnal
Case Report: Kidney injury following non-medical massage
BackgroundDeep tissue massage is widely used for musculoskeletal pain and is generally considered safe. We report a case of acute kidney injury following non-medical deep tissue massage.Case presentationA 50-year-old healthy man presented with acute right lower quadrant abdominal pain 4 h after…
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Artikel Jurnal
Successful use of obinutuzumab in focal segmental glomerulosclerosis with inadequate response to rituximab: a case report
IntroductionPodocytopathies such as minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) remain therapeutic challenges in adults. Although corticosteroids and rituximab (RTX), a chimeric anti-CD20 monoclonal antibody, are effective in most patients, up to 10% show resistance…
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Artikel Jurnal
Treatment practices, characteristics and outcome of immunoglobulin A nephropathy – a Swiss single center experience
IntroductionImmunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis worldwide. Geographic differences in disease course and treatment response are well recognized. The purpose of this analysis was to study clinical and histological characteristics, treatment practices and…
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Artikel Jurnal
Chronic kidney disease in hypertensive patients: the urgent need for targeted interventions in Arab countries: a systematic review
BackgroundChronic kidney disease (CKD) is expected to be the 5th leading cause of years of life lost by 2040. Recently, it emerged as a significant cause of mortality and morbidity, with a high prevalence in Arab countries.ObjectiveAssess CKD among hypertensive (HTN) people in Arab Countries…
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Artikel Jurnal
Primary membranoproliferative glomerulonephritis: natural history, pathogenesis, and treatment
Primary membranoproliferative glomerulonephritis (MPGN) is an ultrarare disease characterized by immunofluorescence microscopy as either immune-complex mediated (IC-MPGN) or C3 glomerulopathy (C3), the latter subdivided by electron microscopy to C3 glomerulonephritis (C3GN) and dense deposit…
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Artikel Jurnal
A behavioral and electrophysiological investigation of conflict monitoring in cystinosis (CTNS gene mutations) using the flanker paradigm
Cystinosis, a rare lysosomal storage disease, is characterized by cystine crystallization and accumulation within tissues and organs, including the kidneys and brain. Its impact on neural function appears mild relative to its effects on other organs, but therapeutic advances have led to…
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Artikel Jurnal
Xeno kidney: revolutionizing kidney disease treatment
The prevalence of end-stage kidney failure has been exponentially increasing, leading to a gross mismatch between the number of patients who may benefit from transplantation and the limited supply of suitable donor organs. As renal transplantation remains a viable and the most effective option for…
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Artikel Jurnal
Complement biomarkers in IgA nephropathy: current insights and clinical relevance
IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide and is a major contributor to the global burden of chronic kidney disease. Strong evidence highlights complement activation as a key driver of the disease pathogenesis and its progression. In this regard, the…
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Artikel Jurnal
Post-transplant ureteral stenosis: donor-related risk factors, graft outcome and surgical management
IntroductionKidney transplantation remains the preferred treatment for end-stage renal disease; however, the increasing use of extended-criteria donors has been associated with a higher incidence of postoperative complications.MethodsWe retrospectively analyzed 471 kidney transplant recipients at…
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Artikel Jurnal
SGLT2 inhibitors as a strategy for volume management in peritoneal dialysis: a case series
Sodium–glucose cotransporter 2 inhibitors (SGLT2i) have demonstrated cardiovascular and renal benefits in chronic kidney disease, yet their role in peritoneal dialysis (PD) remains largely unexplored, and clinical experience is limited. We describe, at the individual-patient level, seven…
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Artikel Jurnal
Anti-GBM disease shortly after clinically presumed ANCA-associated vasculitis in an 85-year-old patient: a case report and literature review
IntroductionSequential emergence of anti-glomerular basement membrane (GBM) disease after anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is rare.Case presentationAn 85-year-old woman presented with fever, edema, elevated myeloperoxidase (MPO)-ANCA, mild urinary…
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Artikel Jurnal
Predictors of renal and patient survival in lupus nephritis: a 28-year single-center cohort study
IntroductionDespite advances in the understanding and treatment of lupus nephritis (LN), long-term renal and patient outcomes remain suboptimal. Identifying reliable predictors of prognosis and early treatment response is essential for improving risk stratification and guiding management.MethodsWe…
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Artikel Jurnal
Gd-IgA1-targeting therapy in IgA nephropathy ~what is pathogenic Gd-IgA1?~
IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis worldwide, and galactose-deficient IgA1 (Gd-IgA1) is widely recognized as the central pathogenic molecule in the current multi-hit model of IgAN. Over the past few decades, advances in our understanding of IgAN…
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Artikel Jurnal
Improvement in peritoneal dialysis exit-site infection rates in an integrated health care system in the United States
IntroductionExit-site infections (ESIs) are a significant complication of peritoneal dialysis (PD) due to their potential to progress to peritonitis, leading to higher rates of morbidity, mortality, and PD dropout. ESI rates and trends have not been generally recorded or reported by established…
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Artikel Jurnal
The lactate dehydrogenase-to-albumin ratio is independently associated with moderate-to-severe tubulointerstitial fibrosis in patients with IgA nephropathy
BackgroundTubulointerstitial fibrosis accelerates the progression of immunoglobulin A nephropathy (IgAN) to end-stage renal disease (ESRD). While renal biopsy is the standard for evaluation, non-invasive biomarkers remain scarce. This study investigated the independent association and diagnostic…