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Journal of Clinical & Translational Ophthalmology
ISSN 2813-1053 · MDPI AG · 32 artikel di indeks
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Combination Treatments for Myopia Progression in Children: A Narrative Review
Despite a growing range of effective monotherapies for childhood myopia control, a subset of children continues to show suboptimal control, prompting interest in combination therapy. This narrative mini-review summarises recent evidence on combining pharmacological, optical, and device-based…
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Multimodal Imaging of Choroidal Tumors: What Ultrasonography Still Uniquely Provides
Choroidal tumors encompass a heterogeneous group of lesions ranging from benign melanocytic nevi and vascular tumors to malignant melanomas and metastatic lesions. Their evaluation increasingly relies on multimodal imaging combining techniques that interrogate different physical and biological…
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Comparing Patient Experiences in Ophthalmic Workflows with Virtual Reality Versus In-Office Standard Testing: A Preliminary Survey Study
Background/Aims: This study set out to compare patient experiences and attitudes toward virtual reality (VR) versus in-office ophthalmic functional testing, as well as their eye exam visit preferences. Methods: A total of 64 patients undergoing a comparative clinical trial including VR and…
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Peripheral Exudative Hemorrhagic Chorioretinopathy: Current Concepts, Multimodal Imaging, Differential Diagnosis and Emerging Therapeutic Perspectives
Peripheral exudative hemorrhagic chorioretinopathy (PEHCR) is an uncommon but likely underrecognized degenerative retinal disorder characterized by peripheral subretinal and sub-retinal pigment epithelium hemorrhagic and exudative lesions, predominantly affecting elderly individuals. The condition…
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Boston Type I Keratoprosthesis with Pars Plana Vitrectomy and Silicone Oil Tamponade for Prephthisical Eyes: A Case Series
Background: Potential vision rehabilitation in patients with hypotony and pre-phthisis remains one of the most challenging issues of ophthalmology. Boston type I keratoprosthesis (KPro) combined with pars plana vitrectomy (PPV) and silicone oil injection (SOI) represents a potential approach to…
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Early Versus Delayed Introduction of Faricimab for Initially Treatment-Naïve Diabetic Macular Edema: A Real-World Pilot Study
Background: Faricimab is one of the most potent anti-vascular endothelial growth factors used in the management of diabetic macular edema (DME). However, real-world benefits regarding its timing and efficacy are still being explored. Methods: This retrospective non-randomized pilot study aimed to…
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Giving the Side-Eye: Asymmetrical Response of the Tear Film Margins to Lateral Gaze Changes
Background: Lateral eye movements are part of natural ocular motility, and their effect on tear film behavior is largely unknown because they are usually not evaluated during tear film examinations, where patients are required to look straight ahead. This study aimed to determine what happens to…
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Clinical Profile of Conjunctival and Eyelid Lesions in Patients Referred to the Ophthalmology Service of the Brazilian Public Health System (SUS)
Introduction: Conjunctival and eyelid lesions encompass a broad spectrum of conditions, ranging from benign entities to malignant neoplasms, and may significantly impact ocular health and quality of life. Their occurrence is influenced by environmental exposure, demographic characteristics, and…
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Predictors of Receiving Surgical Treatment for Neovascular Glaucoma in the California Medicare Population
Background: Population-level predictors of intraocular pressure (IOP)-lowering surgery for neovascular glaucoma (NVG) are understudied. This study examines factors associated with IOP-lowering surgery in California (CA) Medicare beneficiaries with NVG. Methods: The study population included all…
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Strategies for Conformer and Prosthetic Therapy in Children with Acquired Eye Loss and Congenital Microphthalmia or Anophthalmia
Early eye loss, congenital microphthalmia, and anophthalmia can significantly disrupt facial and psychological development in children. Timely intervention with conformers and ocular prostheses is essential for stimulating orbital growth and supporting healthy psychosocial development. This review…
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Structural and Computational Validation of a Novel Titanium Scleral Buckle Implant for Posterior Pole Retinal Detachment
Background: A novel titanium scleral buckle implant (TSBI) was developed for the treatment of posterior pole retinal detachments, analytically modeled and structurally tested as part of preclinical approval studies. The strength and stiffness requirements to apply pressure for retinal reattachment…
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Ophthalmic Effects of Recreational (“Party”) Drugs: Clinical and Translational Perspectives
Recreational (“party”) drug use is prevalent in social environments and is increasingly relevant in ophthalmic care. While the neurological and cardiovascular consequences of these subokstances are well documented, their ocular and visual effects may not be fully recognized or consistently reported…
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Outcome of Unilateral Lateral Rectus Resection in Patients with Age-Related Distance Esotropia
Purpose: We sought to evaluate the surgical outcomes of unilateral lateral rectus (LR) resection among patients with age-related distance esotropia (ARDE). Methods: We conducted a retrospective review of 39 patients who underwent unilateral LR resection for ARDE between January 2019 and November…
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Chronic Posterior Segment Involvement with Retinal Nerve Fiber Layer and Ganglion Cell Loss in Graft-Versus-Host Disease: A Case Report
Background: Graft-versus-host disease is the most common complication after allogeneic hematopoietic stem cell transplantation. While ocular graft-versus-host disease typically manifests as dry eye syndrome and anterior segment involvement, posterior segment complications are rare. Previously…
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Enhancing Ophthalmologists’ Accuracy in Detecting Convergence Insufficiency Using AI-Derived Graphical Outputs
Background: Accurate evaluation of the Near Point of Convergence (NPC) is essential for diagnosing and managing convergence insufficiency (CI). Conventional assessment relies on the patient’s verbal feedback and the examiner’s visual observation, making it subjective and examiner-dependent. The…
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Virtual Reality Enables Rapid and Multi-Faceted Vision Screening in a Pilot Study
Background: Given global population growth and aging, it is imperative to prioritize early eye disease detection and treatment. However, as patient volume increases, providers are facing a shortage of workforce capacity, particularly in areas where eye doctors are already scarce, making it…
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Anterior Segment Variations After Cataract Surgery in Subjects with Primary Open-Angle Glaucoma
Background: The impact of cataract surgery on anterior segment structures in subjects affected by primary open-angle glaucoma (POAG) remains incompletely understood. The aim of this study was to characterize changes in anterior segment parameters after cataract surgery in POAG subjects compared…
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Inaugural Sixth Nerve Palsy in a Patient with Neuroborreliosis: A Case Report
Background: We report an uncommon presentation of Lyme disease and highlight the importance of a detailed history in a patient with new-onset sixth nerve palsy. Methods: Case report and literature review. Results: A 46-year-old man receiving infliximab presented to the ophthalmology emergency…
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Comparison of Visual Acuity and Strabismus Pre- and Post-Baerveldt 350 Glaucoma Drainage Device Placement in Refractory Childhood Glaucomas
Objective: Assess visual acuity (VA) and strabismus changes in children after Baerveldt 350 (BV350) device placement. Methods and Analysis: Retrospective cohort study of children (6-month follow-up. Ocular diagnoses, surgical details, and preoperative and final follow-up exam findings were…
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Impact of Attending Surgeon Experience on Resident-Performed Cataract Surgery Outcomes
Purpose: This study evaluates the association between supervising attending surgeons’ post-residency experience and complication rates during resident-performed phacoemulsification (cataract extraction) surgeries, and to determine whether this relationship changes as the academic year progresses…