195 hasil
Menampilkan 1–20 · 0,33 detik · RSS
Frontiers in Stroke
Scopus
ISSN 2813-3056 · Frontiers Media S.A. · 195 artikel di indeks
-
Artikel Jurnal
Disconnection syndromes and injury to neural systems after ischemic stroke
BackgroundStroke-related impairments present in wide-ranging combinations, including cognitive and upper extremity (UE) sensorimotor deficits, complicating an understanding of their relationship with the anatomy of injury. Here, we hypothesized that deficits in UE sensorimotor function, mood, and…
-
Artikel Jurnal
Interaction between age and atrial fibrillation on ischemic stroke severity: a cross-sectional analysis
BackgroundWhile atrial fibrillation (AF) and older age are established independent risk factors for greater ischemic stroke severity, their interactive effect remains poorly characterized. This study aimed to evaluate the interaction between age and AF status on stroke severity, as measured by the…
-
Artikel Jurnal
CXCL1: a novel therapeutic target to increase aneurysm healing after coil embolization
ObjectiveCXCL1 is highly expressed in human aneurysms but its role in aneurysm healing is unknown. The objective of this study was to determine whether CXCL1 neutralization increases murine aneurysm healing post-coiling.MethodsCarotid artery aneurysms were created in female and male C57BL/6 mice…
-
Artikel Jurnal
Role of C-reactive protein and fibreoptic endoscopic evaluation of swallowing as early markers of stroke-associated pneumonia
IntroductionStroke may result in dysphagia, which can subsequently lead to stroke-associated pneumonia (SaP). This condition has been shown to exert a significant negative impact on patient outcome. Early diagnosis and prevention are therefore desirable.MethodsThis retrospective study compared…
-
Artikel Jurnal
The APOE paradox: divergent genetic influences on hemorrhagic stroke risk—A meta-analysis
BackgroundApolipoprotein E (APOE) regulates lipid metabolism and neuronal repair, yet its alleles show contrasting effects on hemorrhagic stroke (HS) risk. While some variants increase susceptibility, others appear protective, leading to inconsistent findings. This meta-analysis systematically…
-
Artikel Jurnal
Neighborhood economic and demographic landscape as predictors of 90-day outcomes post-stroke hospitalization
ObjectiveAn in-depth exploration of neighborhood environmental impact on post-discharge stroke outcomes is lacking yet essential for identifying populations at high risk. We assess neighborhood economic and demographic characteristics associated with 90-day death or readmission post-stroke…
-
Artikel Jurnal
Relationships between arm and leg real-life activity and clinical assessments in individuals with disabling spasticity after stroke
BackgroundAccelerometer-based measures can provide valuable and objective information about arm and leg use in daily life. This information can be particularly useful in tailoring treatment and rehabilitation in people with disabling spasticity after stroke. To better understand clinical relevance…
-
Artikel Jurnal
Is early thrombectomy of proximal middle cerebral artery occlusion to salvage internal capsule associated with improved clinical outcomes?
BackgroundEloquence of tissue rather than infarct volume is a better predictor of outcomes following proximal middle cerebral artery (MCA) occlusion. The aim of this study was to determine the impact of white matter tract involvement, specifically the internal capsule (IC), following occlusion of…
-
Artikel Jurnal
Comprehensive immunological profiling of acute ischemic stroke during mechanical thrombectomy: myeloid cell activation and molecular signatures in blood and thrombus
BackgroundAcute ischemic stroke (AIS) induces a complex local and systemic inflammatory response; however, most studies rely solely on peripheral blood, providing an incomplete view of immune activity at the occlusion site and within the thrombus.ObjectiveTo characterize immune activation and…
-
Artikel Jurnal
Sex as a predictor and moderator of psychosocial determinants of cardiometabolic risks for Métis People in Canada
IntroductionMétis People, one Indigenous group in Canada, have distinct culture, identity, and experiences. The determinants of Métis People's health, including stroke risk, may differ from other groups. This study examined relationships between psychosocial and lifestyle factors with…
-
Artikel Jurnal
Sex differences in risk factors, stroke etiology, treatment characteristics, and outcomes after endovascular treatment for anterior circulation ischemic stroke
Background and aimsSex-specific differences in vascular risk factors, stroke etiology, and outcomes after endovascular treatment (EVT) remain uncertain. We investigated these differences in a contemporary single-center cohort.MethodsConsecutive patients with acute anterior circulation ischemic…
-
Artikel Jurnal
Outpatient occupational therapy access for rural stroke survivors: barriers as perceived by therapists
AimIdentify occupational therapist (OTs) perceived barriers to occupational therapy (OT) access for rural stroke survivors as well as barriers in stroke specific training of therapists.MethodsAn electronic gap analysis survey was developed and distributed via email.ResultsTwenty-six OTs responded…
-
Artikel Jurnal
Case Report: Flossing intervention for chronic upper limb spasticity after childhood-onset stroke
BackgroundUpper limb spastic paralysis after stroke often limits functional use of the affected hand and restricts activities of daily living, particularly in cases with long-standing impairment following childhood-onset stroke. Although various interventions for spasticity have been reported, many…
-
Artikel Jurnal
A prospective study evaluating clopidogrel resistance among patients with ischemic cerebrovascular events across different ethnic groups in Israel
IntroductionClopidogrel is commonly used for secondary prevention after ischemic cerebrovascular events, but substantial interindividual variability in pharmacodynamics response has been reported. Individuals demonstrating resistance to clopidogrel face a higher likelihood of recurrent ischemic…
-
Artikel Jurnal
Electrophysiological signature of stroke recovery: investigating EEG biomarkers for prognostic insights
IntroductionStroke is a leading cause of long-term disability, often resulting in persistent motor impairments that reflect disruptions in large-scale brain networks. An integrated framework capturing spatiotemporal EEG dynamics would help clarify how these networks change during recovery.MethodsWe…
-
Artikel Jurnal
Reframing moyamoya vasculopathy within steno-occlusive disease of the circle of Willis
Moyamoya disease (MMD) is classically defined by progressive steno-occlusion of the terminal internal carotid artery (ICA) with associated basal collateral networks. Historically, however, this condition was conceptualized in Japan as part of a broader anatomical category—steno-occlusive disease of…
-
Artikel Jurnal
The Quindío stroke network: impact of an integrated care model on mortality and functional outcomes in a middle-income country
IntroductionStroke is a major cause of death and disability worldwide, with low- and middle-income countries bearing the highest burden of this condition. To address regional shortcomings in access to reperfusion therapies-particularly thrombolysis-the Red ACV-Quindío was established as the first…
-
Artikel Jurnal
Beneficial effects of the novel first-in-class compound DX243 on ischemic outcomes following in vitro and in vivo models of stroke
IntroductionNew therapeutic strategies to mitigate the devastating consequences of stroke are urgently needed, as restoration of blood flow is currently the only and limited available treatment.MethodsIn our study, we employed a comprehensive combination of in vitro and in vivo stroke models to…
-
Artikel Jurnal
Closing the stroke care gap: a collaborative, self-sustainable telemedicine enabled model from rural Nepal
BackgroundStroke is a challenging global public health concern, disproportionately affecting people in rural communities. Stroke care is challenging in low and middle-income countries as it requires a coordinated multidisciplinary approach integrating pre-hospital recognition; acute stroke care…