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Exploration of Asthma & Allergy
ISSN 2837-5076 · Open Exploration Publishing Inc. · 135 artikel di indeks
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Climate-driven changes in pollen dynamics: increased loads and earlier, longer exposure
There is unequivocal evidence that the climate is changing, and it is generally accepted that the trend will continue. Climate change is relevant to public health, as it can lead to alterations in the distribution and flowering phenology of plants and to changes in pollen exposure, with subsequent…
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Prevalence and factors associated with work-related asthma among carpenters in Parakou, northern Benin
Aim: Woodworking exposes carpenters to a higher risk of developing asthma or worsening pre-existing asthma. The objective of this study was to determine the prevalence of and factors associated with work-related asthma (WRA) among carpenters in Parakou in 2024. Methods: This was a cross-sectional…
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Allergic conjunctivitis: phenotype, pathophysiology, innate immune pathways, and treatment
Allergic conjunctivitis (AC) is an inflammatory disorder of the ocular surface caused by allergic reactions to environmental substances. It presents with symptoms such as itching, redness of the eye, excessive tearing, and swelling/irritation in the eyes and eyelids. While many AC episodes occur on…
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Is Paris breathing? A scrutiny of the Paris thunderstorm asthma episode of June 2023
Aim: To describe the first major epidemic thunderstorm asthma (ETSA) event detected in France in June 2023. Methods: Data on local meteorology, visits to the emergency room (ER) for asthma and hospitalization after a visit, aerobiological composition of the atmosphere (pollens and spores)…
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Asthma in Italy according to patients and physicians: comments on data collected in the multi-country study APPaRENT2
APPaRENT2 was a multi-country, cross-sectional, online survey of patients with asthma and physicians conducted in five countries (Argentina, Brazil, France, Mexico, and Italy), aimed at assessing physicians’ and patients’ preferred treatment strategies and goals. Education level, age, and place of…
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Biopsychosocial factors, prevention, and treatment strategies in the mental health difficulties of adolescents with asthma
Background: Adolescence is a vulnerable and constantly changing stage of life. Experiencing chronic illnesses such as bronchial asthma during this period can lead to heightened physical, psychological, and social problems in addition to the wide scope of challenges that coincide with the stage. The…
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UpToDate on eosinophils
This review describes the eosinophil journey through the various physiological and pathophysiological phases, from production, maturation, and activation by chemokines and cytokines [especially eotaxin, interleukin (IL)-5, IL-3, and granulocyte-macrophage colony-stimulating factor (GM-CSF)], to…
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Severe scombroid syndrome with biphasic evolution and suspected cardiac involvement in a young woman, a case report
Scombroid syndrome is a frequent cause of fish poisoning and typically presents with mild, self-limiting symptoms. Severe anaphylaxis-like reactions are uncommon, and a biphasic clinical course has not previously been reported. We describe the case of a 19-year-old woman who developed flushing…
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Peanut allergy among schoolchildren in Mexico: findings from a national survey
Peanut allergy (PA) is a significant public health problem in Western countries; however, while some previous work has been conducted in Mexico among specific subgroups, the national prevalence of PA in the Mexican population remains unknown. This ENRADAL-MEX study aimed to estimate the prevalence…
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Pediatric eosinophilic esophagitis
Eosinophilic esophagitis (EoE) is a chronic, immune-mediated inflammatory disease of the esophagus that has emerged as a major cause of esophageal dysfunction in all ages. Over the past two decades, its frequency has increased worldwide, reflecting both heightened recognition and a rise in…
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An expert position paper on environment, occupation and climate change effects on allergic respiratory diseases in Italy
This expert position paper was developed by experts from nine Italian scientific societies with the aim of addressing in an integrated and multidisciplinary way the complex interactions between environmental and occupational exposures, climate change, and the onset of respiratory allergic diseases…
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Using pharmacy electronic communication to identify patients at high risk of asthma exacerbation: a community-based study in Australia and New Zealand
Aim: Asthma exacerbations are associated with significant morbidity and mortality, yet identifying individuals at high risk of an exacerbation remains challenging in community settings. Pharmacists, with access to pharmacy dispensing systems, are well positioned to address this gap. This study…
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Biosimilars in chronic spontaneous urticaria: current evidence, clinical implications and future perspectives
Chronic spontaneous urticaria (CSU) is a debilitating condition characterized by recurrent wheals and/or angioedema lasting more than six weeks without identifiable triggers. The global prevalence is increasing, and patients with resistance to antihistamine therapies experience a significantly…
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Allergy to non-steroidal anti-inflammatories in children: a narrative review of the current models of care
Drug allergies are reported in 10% of children, with non-steroidal anti-inflammatory drugs (NSAIDs) and β-lactam antibiotics being the most frequently implicated; while antibiotic allergy is more commonly reported in early childhood, NSAIDs are the leading cause of confirmed drug hypersensitivity…
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Aeroallergen sensitization patterns and their impact on lung function in adult asthma from a tertiary care centre in Chhattisgarh, India
Aim: This study aimed to assess the prevalence and patterns of aeroallergen sensitisation in steroid-naïve, newly diagnosed adult patients with bronchial asthma using skin prick test (SPT), and to examine its association with lung function parameters measured by oscillometry and spirometry…
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Immunological and epithelial barrier dysfunction in EGPA: the possible role of new biomarkers
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare systemic vasculitis with heterogeneous clinical manifestations. Identifying reliable biomarkers is crucial to predicting disease evolution and guiding therapy. We analyzed clinical, biological, and functional data from 33 patients with…
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Severe cutaneous adverse reactions and their association with autoimmune disease: an update
Severe cutaneous adverse reactions (SCARs), including Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN), drug reaction with eosinophilia and systemic symptoms (DRESS), and acute generalized exanthematous pustulosis (AGEP), are T-cell-mediated hypersensitivity reactions. Although their…
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Lessons from rheumatoid arthritis and inflammatory bowel disease: The importance of patient-centred outcomes in severe asthma
Biologic therapies have transformed care for people with severe asthma, yet treatment response has traditionally been assessed using clinician-derived measures, including lung function, exacerbation rates, and oral corticosteroid use. These metrics, while clinically important, frequently fail to…
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Indoor air pollutant exposure and respiratory health risk assessment in urban healthcare facilities: a comparative study of public and private sectors
Aim: Indoor air quality (IAQ) is a critical component of occupational health in hospitals, where healthcare workers face exposure to particulates and clinical chemical vapours. Prolonged exposure to these environments is linked to an increased incidence of chronic respiratory conditions. This study…
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Climate change as a catalyst: rethinking allergen immunotherapy in a changing world
Climate change is reshaping the epidemiology and severity of allergic disease through mechanisms that extend beyond increased pollen exposure. Pollen seasons are lengthening, annual allergen loads are rising, and tropospheric ozone is chemically modifying pollen proteins in ways that enhance their…