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Clinical Innovations in Health Research-HJM
ISSN 2938-6586 · Publicaciones Permanyer · 48 artikel di indeks
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Artikel Jurnal
CRISPR/Cas9 in clinical practice: opportunities and challenges for Mexico
CRISPR/Cas9 has moved from a gene-editing platform used in experimental biology to a clinically relevant therapeutic technology with approved and investigational applications in hematologic, hepatic, ophthalmologic, and cardiometabolic diseases. The objective of this brief review is to provide a…
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Artikel Jurnal
Quality assessment of cataract surgery results
Evaluation of quality in cataract surgery requires more than finding any improvement in vision. The first variable to analyze is post-operative corrected visual acuity, which should allow the patient to conduct daily activities. Provided that this visual acuity is good, other factors like…
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Artikel Jurnal
Implementation of an integrated laboratory workflow for pulmonary histoplasmosis diagnosis in a Mexican tertiary-care hospital
Background: Histoplasmosis is a systemic fungal infection caused by the Histoplasma complex, endemic in regions of the Americas, including southern Mexico. Although it is the most common endemic mycosis, it remains underdiagnosed, particularly among patients with human immunodeficiency virus…
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Artikel Jurnal
Wilms tumor in adults. Case report and literature review
Wilms tumor is an extremely rare malignant neoplasm in adults, with approximately 300 cases described in this age group. Clinical outcomes are not as favorable as in children, although with the latest treatment protocols; long-term survival rates of approximately 82% have been reported. A…
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Artikel Jurnal
Garengeot hernia: preperitoneal approach in the context of strangulation, case report
Garengeot’s hernia is a femoral hernia in which the cecal appendix is located within the hernial sac; it is most common in adult or postmenopausal women. Its pathophysiology relates to the narrowness of the femoral ring and the abnormal attachment of the cecum, factors that increase the risk of…
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Artikel Jurnal
Handling of biohazardous infectious waste among university students in schools of chemical and health sciences in Mexico
Biohazardous infectious waste (corresponds to Residuos Peligrosos Biológicos Infecciosos [RPBI], in Spanish) management in university settings is critical for safety and regulatory compliance. This systematic review synthesizes evidence on the level of knowledge regarding RPBI management among…
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Artikel Jurnal
Nutritional and cardiovascular risk in older adults
Background: Malnutrition is highly prevalent, often underrecognized in older adults, and may coexist with cardiovascular risk (CR). Traditional anthropometric indicators may not adequately capture this relationship. Objective: This study aimed to determine the prevalence of nutritional risk and to…
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Artikel Jurnal
Proof-of-concept evidence for lncRNA NRIR downregulation in antiphospholipid syndrome and its obstetric subtype
Background/Objetive: Long non-coding RNAs (lncRNAs) regulate immune signaling pathways, including interferon (IFN)-mediated responses implicated in antiphospholipid syndrome (APS). The IFN-inducible lncRNA NRIR (AC017076.5) exhibits context-dependent regulatory functions and has been associated…
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Artikel Jurnal
Evolution from mild symptoms to severe COVID-19 in vaccinated and unvaccinated outpatients in Acapulco, Mexico: follow-up of a case series
Background: Although Coronavirus disease 2019 (COVID-19) vaccine effectiveness and age-related risk of severe disease are well established, real-world evidence from early vaccination phases remains relevant to understand how health systems operated during periods of rapid epidemiological…
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Artikel Jurnal
Functional prognosis in patients with ischemic stroke undergoing reperfusion therapy in the intensive care unit and neurology ward
Background: Patients with acute stroke who receive reperfusion therapy should continue close monitoring of vital signs and neurological status in a stroke unit or intensive care unit (ICU). However, high patient demand and limited space sometimes lead to their admission to a general hospital ward…
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Artikel Jurnal
Mucormycosis in patients with human immunodeficiency virus: an updated systematic review
Background: Mucormycosis is an invasive fungal infection caused by opportunistic pathogenic fungi that affects immunocompromised patients. Objectives: The current review aims to update and complement the data from 2016, with the new PRISMA guidelines, covering the period from 1989 to October 2023…
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Artikel Jurnal
Association of the deficiency of 25-hydroxyvitamin D and the severity of the lung involvement in patients with COVID-19: a systematic review
Background: Almost 4 years have passed since the start of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) pandemic was declared. At present, it has been observed that having the complete vaccination scheme has achieved a decrease in mortality caused by this virus. Nevertheless, it does…
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Artikel Jurnal
Frequency of bile duct injuries according to the Parkland scale: study at Hospital Juárez de México
Background: Cholelithiasis affects 14.3% in Mexico. Cholecystectomy, mostly laparoscopic due to lower risks and quicker recovery, is the second most common surgery in Mexico. Bile duct injury rates have declined to 0.5-1.2% in the past decade. Objectives: Determine the frequency of bile duct…
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Artikel Jurnal
Coinfection and predominant symptoms of Respiratory Syncytial Virus infection in the COVID-19 era, pediatric report in México City
Background: The respiratory syncytial virus (RSV) is the main viral etiological agent for respiratory infections and, with the measures implemented by the severe acute respiratory syndrome coronavirus 2 pandemic, it had decreased with social distancing, strict hygiene, and the use of masks and all…
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Artikel Jurnal
Altered metabolic parameters and dietary patterns in women with uterine myomatosis
Background: Obesity has been described as a risk factor for uterine myomatosis (UM). This has prompted studies to determine whether alterations in different metabolic parameters, usually associated with obesity, are related to the development of myomatosis. Likewise, it is suggested that dietary…
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Artikel Jurnal
Extracorporeal photopheresis reduces clinical signs of chronic graft versus host disease in pediatric patients: a case series report
Background: Graft versus Host Disease (GVHD) is a frequent pathology that affects around 60% of patients who receive allogeneic hemopoietic stem cell transplantation. The first-line treatment is corticosteroids. However, some of the patients are or become resistant to this therapy. Extracorporeal…
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Artikel Jurnal
A complete type 2 diabetes remission by following a Mexican traditional diet. A case report
Type 2 diabetes (T2D) complete remission is defined as normoglycemia for at least 1 year, in the absence of active pharmacologic or surgical therapy. This report describes a complete remission case, which was achieved through a Mexican traditional diet and last for 4 years. Mexican traditional diet…