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JHLT Open
Scopus
ISSN 2950-1334 · Elsevier · 611 artikel di indeks
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Artikel Jurnal
Ex vivo lung perfusion in donation after circulatory death lung transplantation: A systematic review and meta-analysis
Background: Lung transplantation is the definitive therapy for end-stage lung disease, but donor shortages contribute to high waiting list mortality. Donation after circulatory death (DCD) expands the donor pool, and ex vivo lung perfusion (EVLP) enables graft assessment and optimization. However…
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Artikel Jurnal
Exercise capacity after mechanical circulatory support compared to heart transplant in advanced heart failure
Background: In patients with advanced heart failure, it is assumed that orthotopic heart transplant (OHTx) results in greater exercise capacity compared to ventricular assist device (VAD), however this has not been formally examined. In this study, we evaluated the exercise capacity of patients…
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Artikel Jurnal
Outcomes and management strategies of pregnancies after heart and lung transplantation across Europe
Background: Literature on pregnancy after heart and/or lung transplantation (heart transplantation (HTx), lung transplantation (LTx), heart lung transplantation (HLTx)) remains sparse. This study assessed short- and long-term outcomes of pregnancies post-thoracic organ transplantation across Europe…
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Artikel Jurnal
Association between genetics variants and clinical outcomes in patients with left ventricular assist device
Background: Left ventricular assist device (LVAD) implantation is a life-saving therapy for end-stage heart failure, but right ventricular failure (RVF) remains a major complication. Current RVF risk models are limited. We hypothesized that pathogenic/likely pathogenic (P/LP) variants increase…
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Artikel Jurnal
Listing patterns at the highest volume heart transplant centers: Multiple roads to transplant
The current heart transplantation (HT) allocation system added additional progressive statuses to differentiate the highest risk patients and decrease waitlist mortality. We analyzed United Network for Organ Sharing thoracic organ data (10/18/2018-6/30/2025) to assess listing practices at the 10…
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Artikel Jurnal
Impact of cardiac resynchronization therapy in patients with left ventricular assist devices: A systematic review and meta-analysis
Background: Many patients with left ventricular assist devices (LVADs) have cardiac resynchronization therapy (CRT). However, the impact of CRT on their clinical and hemodynamic outcomes remains unclear. Methods: We conducted a systematic review and meta-analysis to evaluate CRT's impact on…
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Artikel Jurnal
An international perspective on allocation rules for combined heart-lung transplantation
While the global numbers of lung transplants have increased, the annual numbers of heart-lung transplants have steadily declined over the last decades, combined transplants globally being only about 2% of heart or lung transplant numbers. Although patients eligible for a combined heart-lung…
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Artikel Jurnal
Abnormal spirometry 1 year after lung transplantation may identify patients at risk for chronic lung allograft dysfunction in a multicenter cohort
Background: Baseline lung allograft dysfunction (BLAD) is the failure to achieve predicted pulmonary function after lung transplantation. BLAD, as defined by abnormal spirometry at 12 months post-transplant (Spiro12M), has been associated with increased mortality and chronic lung allograft…
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Artikel Jurnal
The unsung heroes: A scoping review of the experiences of lung transplant informal caregivers
Informal caregivers support patients after lung transplantation (LTx). With growing recognition of the multiple demands placed on caregivers, this scoping review aimed to systematically map the literature surrounding informal caregiving experiences after LTx using JBI guidelines. Multiple databases…
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Artikel Jurnal
Contemporary evidence to inform management of deceased potential thoracic organ donors after brain death
Brain death triggers profound physiologic derangements that threaten organ viability and contribute to the persistent shortage of transplantable thoracic organs. This narrative review synthesizes contemporary evidence informing the management of deceased potential thoracic organ donors after brain…
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Artikel Jurnal
Differences in mortality by donor sex and age in heart transplantation: An individual patient data meta-analysis
Background: Prior studies suggested a recipient sex-dependent association between donor sex and heart transplant survival. We hypothesized that donor age also modifies the association between donor sex and recipient mortality. Methods: Deceased donor heart transplant recipients (1988-2019, n =…
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Artikel Jurnal
Survival improvement with sirolimus plus tacrolimus immunosuppression for treatment of bronchiolitis obliterans syndrome after lung transplantation
Background: Chronic rejection, usually manifesting as bronchiolitis obliterans syndrome (BOS), is the leading cause of death among lung transplant patients. Prior lung transplant studies showed higher overall survival and lower BOS incidence associated with sirolimus (SIR) + tacrolimus (TAC) versus…
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Artikel Jurnal
Medium-term comprehensive outcomes of heart transplantation using donors with hepatitis C viremia to aviremic recipients
Background: Although direct-acting antiviral (DAA) therapy has enabled successful use of organs from donors with hepatitis C (HCV) with favorable initial results, medium-term outcome data remains insufficient. This study aimed to compare 4-year mortality, primary graft dysfunction, and major…
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Artikel Jurnal
Kaposi sarcoma in lung transplant recipients with public health service increased-risk donors: A retrospective cohort study and review of the literature
Purpose: To investigate the relationship between Public Health Service (PHS) increased-risk donors and post-lung transplant (LT) Kaposi sarcoma (KS). Methods: This retrospective cohort study included LT recipients (April 1, 2019-April 1, 2024) who had PHS increased-risk donors at our institution…
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Artikel Jurnal
Safety and efficacy of sodium-glucose cotransporter 2 inhibitors in post-heart transplant patients: A multi-center retrospective cohort study
Background: Despite compelling mechanistic and clinical data supporting the use of sodium glucose cotransporter 2 inhibitors (SGLT2i) in heart failure, chronic kidney disease (CKD), and type 2 diabetes (T2DM), the safety and efficacy of SGLT2i in patients with prior orthotopic heart transplant…
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Artikel Jurnal
Macitentan and phosphodiesterase-5 inhibitor alone or in combination in newly diagnosed pulmonary arterial hypertension: a pooled analysis
INTRODUCTION: Upfront combination therapy with endothelin receptor antagonist (ERA) and phosphodiesterase-5 inhibitor (PDE5i) is guideline-recommended for low- or intermediate-risk pulmonary arterial hypertension (PAH). This study compared time to all-cause mortality for macitentan+PDE5i…
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Artikel Jurnal
Percutaneous management and outcomes of outflow graft obstruction in patients with left ventricular assist device: A single-center experience
Background: Outflow graft obstruction (OGO) is a rare but potentially fatal complication of left ventricular assist device (LVAD) therapy. Timely diagnosis and intervention are critical to prevent hemodynamic compromise and death. Methods: We retrospectively reviewed 191 LVAD patients treated…