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Journal

Comparative Immunology Reports

Scopus

ISSN 2950-3116 · Elsevier · 168 articles in the index

  1. Journal Article

    Interactive effect of dietary formic acid and fenugreek on growth performance, immune response, and disease resistance in Nile tilapia challenged with

    Hussein M.K. Al-Mohammad; Dooha K. Alshamarey; Ahmed J. Obaid et al.

    Comparative Immunology Reports, Vol. 11 · 2026 · English · DOAJ Scopus

    This study investigated the interactive effects of dietary formic acid (FA) and fenugreek (FG) supplementation on growth performance, hematological and biochemical parameters, antioxidant status, innate immune response, and disease resistance in Nile tilapia ( Oreochromis niloticus ) challenged…

  2. Journal Article

    Optimization of immune priming interval using Imuno-FS Plus enhances the efficacy of oral formalin-killed

    Annisa Widya Ananda; Sri Nuryati; Dinamella Wahjuningrum et al.

    Comparative Immunology Reports, Vol. 11 · 2026 · English · DOAJ Scopus

    Acute hepatopancreatic necrosis disease (AHPND), caused by toxigenic Vibrio parahaemolyticus, remains a major constraint in Pacific white shrimp ( Litopenaeus vannamei ) aquaculture. This study evaluated whether the interval between adjuvant-induced immune priming and oral vaccination could be…

  3. Journal Article

    A multi-omics integrated analysis reveals the effects of adding

    Zehui Su; Runze He; Ping Shen et al.

    Comparative Immunology Reports, Vol. 11 · 2026 · English · DOAJ Scopus

    With the widespread adoption of high-density, intensive farming systems, environmental stressors in Parabramis pekinensis farming have become increasingly severe, leading to intestinal dysfunction, reduced digestive and absorptive capacity, and frequent outbreaks of disease. This study aimed to…

  4. Journal Article

    Ancestral roles of the classical complement pathway uncovered through functional analysis of factor D-depleted carp serum

    Akhil Kizhakkumpat; Michiyo Kimura; Takahiro Nagasawa et al.

    Comparative Immunology Reports, Vol. 10 · 2026 · English · DOAJ Scopus

    The complement system of jawed vertebrates comprises three activation routes—classical (CP), lectin (LP), and alternative (AP) pathways—yet the functional architecture of these cascades in early vertebrates remain insufficiently defined. Although the AP is often considered dominant in early…

  5. Journal Article

    Edwardsiella virulence protein P modulates immune response and cell death in Japanese medaka, Oryzias latipes

    Takechiyo Sumiyoshi; Aki Nishihara; Chikara Irishika et al.

    Comparative Immunology Reports, Vol. 10 · 2026 · English · DOAJ Scopus

    Edwardsiellosis, caused by Edwardsiella piscicida, leads to major losses in global aquaculture, and understanding its infection mechanisms is critical for effective disease control. The type VI secretion system (T6SS) effector Edwardsiella virulence protein P (EvpP) is a key virulence factor that…

  6. Journal Article

    A lymphoid organ-enriched C-type lectin, functions as a pattern recognition receptor and inflammatory regulator in Litopenaeus vannamei

    Xiaoyang Huang; Yuan Liu; Yi Li et al.

    Comparative Immunology Reports, Vol. 10 · 2026 · English · DOAJ Scopus

    Crustacean C-type lectins (CTLs) constitute a versatile receptor family that play key roles in innate immune recognition. Here, a C-type lectin LvccCTL, primarily expressed in the lymphoid organs, was identified and characterized from the Pacific white shrimp Litopenaeus vannamei. LvccCTL contained…

  7. Journal Article

    Pseudoalteromonas sp. SRSBD1_22: A potent prophylactic candidate mediating lipopolysaccharide (LPS) based humoral immune response in Penaeus monodon against WSSV infection

    H M Rakibul Islam; Mizanur Rahman Washim; Md. Shoebul Islam et al.

    Comparative Immunology Reports, Vol. 10 · 2026 · English · DOAJ Scopus

    White Spot Disease (WSD), a disease caused by White Spot Syndrome Virus (WSSV), a devastative killer in shrimp farms, causing a severe economic loss to the farmers. This study investigated the immune enhancing activity of lipopolysaccharides (LPS) against WSSV infection, extracted from a newly…

  8. Journal Article

    Bibliometric analysis of vaccine research trends in aquaculture

    Seong Wei Lee; Wendy Wee

    Comparative Immunology Reports, Vol. 10 · 2026 · English · DOAJ Scopus

    Aquatic animal health management remains a major challenge in aquaculture, largely due to the continued reliance on traditional approaches such as antibiotics, which contribute to the emergence of antimicrobial-resistant bacteria in the environment. Vaccination has emerged as a more sustainable and…

  9. Journal Article

    Family-based transcriptomic profiling of Atlantic salmon skin and head kidney in response to Lepeophtheirus salmonis infestation under physiological and elevated temperatures

    Reza Ghanei-Motlagh; Wenlong Cai; Jordan D. Poley et al.

    Comparative Immunology Reports, Vol. 10 · 2026 · English · DOAJ Scopus

    This study explored transcriptomic alterations in the skin and head kidney of Atlantic salmon (Salmo salar) from multiple families in response to infestation with the salmon louse (Lepeophtheirus salmonis) at the chalimus and adult stages, under elevated (20 °C) versus standard (10 °C) temperature…

  10. Journal Article

    The predicted transcription factors of the immune-related genes in Pacific white shrimp (Litopenaeus vannamei) respond to Fusarium solani infection

    Yusuf Jibril Habib; Akram Ismael Shehata; Chengjie Yao et al.

    Comparative Immunology Reports, Vol. 10 · 2026 · English · DOAJ Scopus

    Aquatic organisms need immune-related genes to fight infections. In response to pathogenic challenges, transcription factors activate or repress immune-related genes at the right time and in the right amounts. In this study, we will identify and describe the transcription factors that govern…

  11. Journal Article

    Transcriptomic analysis of shrimp immune modulation by dietary inactivated microbial cells and Sargassum sp. immunostimulants

    M.A. Amatul-Samahah; F.M.I. Natrah; M.N.A. Amal et al.

    Comparative Immunology Reports, Vol. 10 · 2026 · English · DOAJ Scopus

    Research on the shrimp immune system has piqued attention in recent years, as a better understanding of the events that occur in the shrimp immune system could assist to improve shrimp's overall health and, as a result, increase shrimp production output. This study focuses on Litopenaeus vannamei…

  12. Journal Article

    Transcriptome analysis reveals the role of host cell adhesion molecules in Scophthalmus maximus defense against Aeromonas salmonicida infection

    Dong Sheng; Yuxiao Liu; Xu Ren et al.

    Comparative Immunology Reports, Vol. 10 · 2026 · English · DOAJ Scopus

    The primary pathogen responsible for considerable economic losses in the farming of Scophthalmus maximus is Aeromonas salmonicida. To explore the initial immune response to an A. salmonicida infection in turbot, researchers utilized Illumina NovaSeq 6000 technology. In total, 2636 genes with…

  13. Journal Article

    Effects of the amino acid mixture on growth performance, non-specific immunity and intestinal health in Pacific white shrimp (Litopenaeus vannamei)

    Chengjie Lv; Jiali Wu; Yongliang Liu et al.

    Comparative Immunology Reports, Vol. 10 · 2026 · English · DOAJ Scopus

    In the present study, a mixture of amino acids (NutriMix, composed of 42% arginine, 39% lysine, and 19% methionine) was used to evaluate its effects on growth performance, non-specific immunity and intestinal health in Pacific white shrimp (Litopenaeus vannamei). In a 42-day feeding trial, shrimp…

  14. Journal Article

    A histone deacetylase CgHDAC11 regulates CgIL17 expression in the immune response of Pacific oyster (Crassostrea gigas)

    Luyi Lun; Xingye Lian; Weilin Wang et al.

    Comparative Immunology Reports, Vol. 10 · 2026 · English · DOAJ Scopus

    As an important enzyme catalyzing histone deacetylation, histone deacetylase 11 (HDAC11) can modulate chromatin accessibility and play important roles in the transcriptional regulation, which further regulates many physiological processes including immune memory and embryo development in…

  15. Journal Article

    Strategic integration of SOPs, harmonizing pond management, water quality, and disease resilience in semi-intensive shrimp farming: A Bangladeshi perspective

    Md. Mer Mosharraf Hossain; Ritu Rani Ghosh; Bipul Kumar Sen et al.

    Comparative Immunology Reports, Vol. 10 · 2026 · English · DOAJ Scopus

    To address chronic low productivity, recurrent disease outbreaks including White Spot Syndrome Virus and Vibrio infections, and persistent water quality instability in Bangladesh’s semi intensive Penaeus monodon farming systems, this study develops and field validates regionally customized Standard…

  16. Journal Article

    Characterization of MACPF domain containing proteins in oyster Crassostrea gigas and their expression profile in response to immune stimulation

    Si Liu; Weilin Wang; Luyi Lun et al.

    Comparative Immunology Reports, Vol. 10 · 2026 · English · DOAJ Scopus

    Membrane attack complex/perforin (MACPF) domain containing proteins play crucial roles in the immune systems of various organisms, but their identification, classification and functions in oysters remain largely unknown. This study screened the MACPF domain containing proteins in the genome of…

  17. Journal Article

    Effective immunostimulant for rainbow trout after short term usage: Lepidium sativum and its by-product

    Mabrokah Adrees Rafallah Saed; Soner Bilen; Osman Nezih Kenanoğlu et al.

    Comparative Immunology Reports, Vol. 10 · 2026 · English · DOAJ Scopus

    In the present study, garden cress (Lepidium sativum) cold-pressed seed oil and its pulp ethanolic extract, obtained as a by-product, were evaluated as dietary immunostimulants in rainbow trout (Oncorhynchus mykiss). Fish were fed an unsupplemented control diet or diets containing garden cress seed…

  18. Journal Article

    QuantStudio™ 12K flex OpenArray™ chip as a tool for high-throughput immunogene expression analysis in chinook salmon Oncorhynchus tshawytscha

    Xiaoqing Dang; Yubing Chen; Shahinur S. Islam et al.

    Comparative Immunology Reports, Vol. 10 · 2026 · English · DOAJ Scopus

    Salmon aquaculture is the fastest growing food production system globally, increasing the need for efficient disease management strategies. In this study, a high-throughput OpenArray™ TaqMan® RT-qPCR platform for quantifying inflammatory gene expression in Oncorhynchus tshawytscha (Chinook salmon)…

  19. Journal Article

    Thermal modulation of genetic resistance to infectious salmon anemia virus: Transcriptome analyses of Atlantic salmon families (Salmo salar) at 10 °C and 20 °C

    E Misk; SK Whyte; SL Purcell et al.

    Comparative Immunology Reports, Vol. 10 · 2026 · English · DOAJ Scopus

    Understanding the interaction between genetic resistance and environmental temperature is critical for managing infectious salmon anemia virus (ISAv) in Atlantic salmon aquaculture. Building upon an experimental infection trial of 20 families with ISAv HPR4 at 10 °C and 20 °C, we conducted RNA…

  20. Journal Article

    Oral vaccines for rainbow trout: Promising solutions to combat bacterial and viral pathogens in aquaculture

    Mahboobeh Nazari; Mahmood Jeddi-Tehrani

    Comparative Immunology Reports, Vol. 10 · 2026 · English · DOAJ Scopus

    Oral vaccination represents a transformative approach for disease prevention in rainbow trout aquaculture, offering the promise of mass immunization with minimal handling stress and improved welfare. As rainbow trout remain a cornerstone species in global aquaculture, infectious diseases such as…