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Biomedical Analysis
Scopus
ISSN 2950-435X · KeAi Communications Co., Ltd. · 57 artikel di indeks
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Artikel Jurnal
Precision design and translational progress of lipid-based soft nanomaterials for targeted breast cancer chemotherapy
Systemic toxicity and the development of drug resistance limit conventional chemotherapy, and breast cancer remains a major global health problem. As the materials community pushes towards precision engineering at the nanoscale, lipid nanoparticles have emerged as novel soft matter platforms that…
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Artikel Jurnal
Superstructured nanomaterials for disease biomarker detection: Design principles and analytical modalities
Superstructured nanomaterials are hierarchical architectures assembled from functional building blocks through tailored physicochemical interactions or spatial confinement strategies. This review presents the structure-performance relationships of superstructured nanomaterials and their…
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Artikel Jurnal
Portable detection of vitamin B12 using fluorescence quenching method of boron and nitrogen co-doped carbon dots
A portable sensing method for vitamin B12 (VB12) was constructed based on B and N co-doped carbon dots (B, N-CDs). B, N-CDs were synthesized by a one-step hydrothermal method with 3-aminophenylboronic acid (3-APBA) and p-hydroxybenzaldehyde as precursors. B, N-CDs exhibited good water…
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Artikel Jurnal
Label-free enrichment and identification of circulating tumor cells integrating inertial microfluidics and deep learning
Circulating tumor cells (CTCs) hold great promise as liquid biopsy biomarkers for cancer diagnosis and treatment monitoring. However, their efficient enrichment and accurate identification from blood remain challenging due to their extreme rarity and the complex background of blood cells. Herein…
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Artikel Jurnal
Preparation and evaluation of bovine serum albumin-protected copper sulfide nanoparticles
This study aimed to prepare bovine serum albumin (BSA)-protected copper sulfide nanoparticles (CuS@BSA), systematically characterize their physicochemical properties, and preliminarily evaluate their in vitro antitumor activity, providing an experimental basis for the development of…
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Artikel Jurnal
Microfluidic flow cytometry toward point-of-care testing: advances in fluid driving, cell focusing, signal detection, and data analysis
Microfluidic technologies, with advantages in low sample consumption, controllable fluid manipulation, structural integration, and system miniaturization, provide a promising route for adapting flow cytometry to point-of-care testing (POCT). Nevertheless, the practical adaptation of microfluidic…
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Artikel Jurnal
Development of a certified reference material for Angiotensin Ⅱ with the mass balance method and isotope dilution mass spectrometry method
Angiotensin Ⅱ, the primary effector of the renin-angiotensin-aldosterone system, plays a significant role in blood pressure regulation and fluid-electrolyte homeostasis. It also serves as a crucial biomarker for vascular diseases. To ensure the metrological traceability and international…
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Artikel Jurnal
Progress in non-endocytic dependent transmembrane delivery of biological macromolecules
Biomacromolecules—including proteins, nucleic acids, and gene-editing tools—have demonstrated immense potential for therapeutic applications. However, their intracellular bioavailability is severely constrained by the cell membrane, which acts as a natural barrier to macromolecular entry…
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Artikel Jurnal
Ameliorative effects of silver nanoparticles on hyperglycemia-induced cellular stress in gangrene
Diabetes-induced hyperglycemia leads to oxidative stress, inflammation, and impaired wound healing, particularly in gangrene. In this study, silver nanoparticles (AgNPs) were synthesized using flower extracts of Ixora coccinea and Rhododendron arboreum (IR-AgNPs) through a microwave-assisted green…
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Artikel Jurnal
Machine learning driven multi omics and probiotic integration for precision colorectal cancer management
Colorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide, driven by tumor heterogeneity, late-stage detection, and variable therapeutic response. The integration of machine learning (ML) with multi-omics and probiotic research offers a transformative pathway toward…
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Artikel Jurnal
Direct mass spectrometry for traditional Chinese medicine analysis: Analytical strategies, applications, and future perspectives
Direct mass spectrometry has become an important analytical approach in traditional Chinese medicine (TCM) because it enables rapid, direct, and minimally destructive characterization with little or no chromatographic pretreatment. In current TCM research, Direct mass spectrometry has shown clear…
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Artikel Jurnal
Preparation and evaluation of iRGD-modified PLGA-PEG nanoparticles encapsulating TPEN
This study developed an iRGD-modified PLGA-PEG nanoparticle for targeted delivery of the metal chelator N,N,N′,N′-tetrakis(2-pyridylmethyl)ethylenediamine (TPEN). Different from conventional nanoplatforms that rely on exogenous copper delivery to induce cuproptosis, this work focuses on…
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Artikel Jurnal
The application advances of highly efficient signal amplification methods in the detection of active DNA demethylation products
DNA methylation and active demethylation are key epigenetic mechanisms that dynamically regulate gene expression in multicellular organisms. Intermediates of active DNA demethylation—5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC)—are essential for genomic…
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Artikel Jurnal
pH-responsive antibacterial biomedical platform based on SH@ZIF-8/AgNPs promotes healing of infected wounds
Infected wounds feature an acidic microenvironment, providing an endogenous stimulus for targeted therapy. Taking advantage of the acid-triggered decomposition of zeolitic imidazolate framework-8 (ZIF-8), we constructed a pH-responsive theranostic composite (denoted as SH@ZIF-8/AgNPs, with shikonin…
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Artikel Jurnal
Development of nanogold immunochromatographic assay strip based on novel nanobody for rapid detection of imazalil in food and environmental water samples
The misuse of the broad-spectrum fungicide imazalil (IMZ) poses significant challenges to food safety and environmental safety, which requires rapid and accurate methods for detecting IMZ in complex food matrix and environmental samples. Herein, a novel anti-IMZ nanobodies (Nbs) with excellent…
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Artikel Jurnal
Preparation and characterization of phenylboronic acid cross-linked hydrogel
Hydrogels demonstrate significant value in the biomedical field, particularly in wound management and tissue engineering, owing to their unique three-dimensional network structure, excellent biocompatibility, and functional design flexibility. This study successfully developed a multifunctional…
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Artikel Jurnal
Unsupervised classification based on m7G-related lncRNAs reveals molecular subtypes of patients with hepatocellular carcinoma
The m7G methylation has been demonstrated to play a crucial role in the progression of various tumors. Therefore, we performed molecular subtyping of hepatocellular carcinoma (HCC) patients based on m7G-related lncRNAs. We obtained transcriptomic data of HCC patients from the TCGA database and…
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Artikel Jurnal
A review of extraction, synthesis, and pharmacological activities of naringenin and its derivatives
Naringenin, a polyphenolic flavanone, exhibits diverse pharmacological and biological activities, including anti-inflammatory, antioxidant, anti-obesity, anticancer, antidiabetic, and antimicrobial effects. This review provides a comprehensive overview of the structural characteristics, extraction…