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  1. Journal Article Full text

    Identifying driving mechanisms and threshold effects of trade-offs and synergies among ecosystem services: A case study of Henan Province, China

    Doudou Dong; Chunyi Li; Jun Du et al.

    PLOS One, Vol. 21 No. 4 · 2026 · English · PLOS Scopus

    Ecosystem services (ESs) exhibit complex interactions with multiple driving factors, including human activities, climate change, land use, soil erosion, and slope. Henan Province faces ecological challenges such as water scarcity, soil erosion, and biodiversity degradation. Using Henan Province as…

  2. Journal Article Full text

    Emergency department attendance by callers to NHS111 who end the call prior to triage: A time-to-event-analysis

    Richard Pilbery; Jen Lewis; Rebecca Simpson

    PLOS One, Vol. 21 No. 4 · 2026 · English · PLOS Scopus

    Background: The English National Health Service (NHS) 111 telephone service aims to assist members of the public with urgent medical care needs. However, each year nearly 18% of the 20.6 million calls to NHS 111 are abandoned prior to speaking to a health advisor. There are concerns that callers…

  3. Journal Article Full text

    Understanding older adults’ perception, acceptance, and adoption of smart home technologies

    Pireh Pirzada; Adriana Wilde; Gayle H. Doherty et al.

    PLOS One, Vol. 21 No. 4 · 2026 · English · PLOS Scopus

    Smart home technologies have increased in popularity and affordability in recent years, however, there is limited research on their adoption specifically among older adults. This study aims to uncover incentives and barriers to the adoption of smart home components, given the impact of COVID-19 on…

  4. Journal Article Full text

    Nursing students’ readiness and training needs for interprofessional education: A cross-sectional study in South Korea

    Sun-Yi Yang

    PLOS One, Vol. 21 No. 4 · 2026 · English · PLOS Scopus

    The significance of interprofessional education (IPE) in fostering interprofessional collaboration is being increasingly emphasized in healthcare. This study analyzed the training needs of nursing students based on the Interprofessional Education Collaborative Core Competencies using a descriptive…

  5. Journal Article Full text

    Fatty acid and melatonin-enriched warming: A novel approach using vitrified oocytes and early-stage embryos for patients with poor prognosis

    Yoo Ra Ko; Soyoung Kim; Jinkyeong Ha et al.

    PLOS One, Vol. 21 No. 4 · 2026 · English · PLOS Scopus

    Background: Cryopreservation and warming can induce cellular stress that impairs oocyte and embryo competence, particularly in poor-prognosis patients. Although fatty acids and melatonin have been proposed to support cytoskeletal stability and reduce oxidative stress, their combined use during…

  6. Journal Article Full text

    Contamination of medical devices and hospital environments with free-living amoebae: Evidence from hospitals in Northwestern Iran

    Hamed Behniafar; Adel Spotin; Ali Bahadori et al.

    PLOS One, Vol. 21 No. 4 · 2026 · English · PLOS Scopus

    Free-living amoebae (FLAs) are ubiquitous protozoa found in soil, air, and artificial systems, including hospital environments. Some genera of free-living amoebae, such as Acanthamoeba, can cause severe health complications, including Acanthamoeba keratitis and granulomatous amoebic encephalitis…

  7. Journal Article Full text

    Zeolitic imidazolate frameworks (ZIF-8) as a carrier in a topical ocular delivery system for the treatment of ocular diseases

    Phillip A. Harding; James H. Westbay; Ethan Fletcher et al.

    PLOS One, Vol. 21 No. 4 · 2026 · English · PLOS Scopus

    Current systems for topical ocular drug delivery enable non-invasive administration of therapeutics to the eye but suffer from poor permeability and bioavailability, limiting therapeutic efficacy. Metal-organic frameworks are porous, crystalline materials that can serve as drug delivery systems and…

  8. Journal Article Full text

    Sugar, mineral, B-vitamins profiles and radical scavenging activity of Royal jelly collected at different harvesting times

    Eyuel Welelaw; Abera Belay; Tadele Alemu et al.

    PLOS One, Vol. 21 No. 4 · 2026 · English · PLOS Scopus

    Royal jelly is produced by young worker honeybees that support the growth of their larvae. Human beings can harvest and use it as functional food due to its high content of nutrients and beneficial human health effects. This study aims to investigate how harvesting time affects sugar and minerals…

  9. Journal Article Full text

    Rurality representation and changes in rural tourism destination

    Xueting Hong; Zhenfang Huang; Xinyi Li et al.

    PLOS One, Vol. 21 No. 4 · 2026 · English · PLOS Scopus

    Representation of rurality plays a crucial role in developing rural tourism. However, the connotations of rural destinations and how such representations shift across different social contexts remains unclear. This study aims to examine the rurality of, and changes in, rural tourism destinations…

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