52 hasil untuk "Isabela RAMOS"
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Artikel Jurnal Teks lengkap
Silencing of the 20S proteasomal subunit-α6 triggers full oogenesis arrest and increased mRNA levels of the selective autophagy adaptor protein p62/SQSTM1 in the ovary of the vector Rhodnius prolixus
The high reproductive rates of insects contribute significantly to their ability to act as vectors of a variety of vector-borne diseases. Therefore, it is strategically critical to find molecular targets with biotechnological potential through the functional study of genes essential for insect…
Juga tersedia di: DOAJ
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Artikel Jurnal
Manejo das Hemorragias Relacionadas aos Anticoagulantes Orais de Ação Direta
Introdução: Os anticoagulantes orais diretos (direct oral anticoagulant – DOACs) são uma nova classe de anticoagulantes que inibem diretamente a trombina (dabigatran) ou o fator Xa (rivaroxabana, edoxabana e apixabana) na cascata da coagulação. Esses estão sendo cada vez mais utilizados para…
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Artikel Jurnal Teks lengkap
Silencing of RpATG6 impaired the yolk accumulation and the biogenesis of the yolk organelles in the insect vector R. prolixus.
In oviparous animals, the egg yolk is synthesized by the mother in a major metabolic challenge, where the different yolk components are secreted to the hemolymph and delivered to the oocytes mostly by endocytosis. The yolk macromolecules are then stored in a wide range of endocytic-originated…
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Artikel Jurnal
Functional characterization of maternally accumulated hydrolases in the mature oocytes of the vector Rhodnius prolixus reveals a new protein phosphatase essential for the activation of the yolk mobilization and embryo development
Yolk biogenesis and consumption have been well conserved in oviparous animals throughout evolution. Most egg-laying animals store yolk proteins within the oocytes’ yolk granules (Ygs). Following fertilization, the Ygs participate in controlled pathways of yolk breakdown to support the developing…
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Artikel Jurnal Teks lengkap
Acidocalcisomes as Calcium- and Polyphosphate-Storage Compartments during Embryogenesis of the Insect Rhodnius prolixus Stahl
Background: The yolk of insect eggs is a cellular domain specialized in the storage of reserve components for embryo development. The reserve macromolecules are stored in different organelles and their interactions with the embryo cells are mostly unknown. Acidocalcisomes are lysosome-related…
Juga tersedia di: DOAJ
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Knockdown of carnitine palmitoyltransferase I (CPT1) reduces fat body lipid mobilization and resistance to starvation in the insect vector Rhodnius prolixus
The energy stored in fatty acids is essential for several critical activities of insects, such as embryogenesis, oviposition, and flight. Rhodnius prolixus is an obligatory hematophagous hemipteran and vector of Chagas disease, and it feeds infrequently on very large blood meals. As digestion…
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Artikel Jurnal
FATORES ASSOCIADOS A ÓBITO E INCAPACIDADE POR NEURO-CHIKUNGUNYA NA TRÍPLICE EPIDEMIA DE ARBOVIROES NO NORDESTE DO BRASIL: ESTUDO DE COORTE
Introdução e objetivos: O potencial do vírus chikungunya (CHIKV) causar doenças neurológicas, que podem resultar em óbito ou incapacidade, é cada vez mais reconhecido pelos médicos, particularmente em áreas endêmicas. Nós descrevemos os fatores de risco associados a óbito e incapacidade de 71…
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Artikel Jurnal
Deficiency of Acetyl-CoA Carboxylase Impairs Digestion, Lipid Synthesis, and Reproduction in the Kissing Bug Rhodnius prolixus
Rhodnius prolixus is a hematophagous insect, vector of Chagas disease. After feeding, as blood is slowly digested, amino acids are used as substrates to fuel lipid synthesis, and adult females accumulate lipids in the fat body and produce eggs. In order to evaluate the importance of de novo fatty…
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Artikel Jurnal
In the fed state, autophagy plays a crucial role in assisting the insect vector Rhodnius prolixus mobilize TAG reserves under forced flight activity
Autophagy is a cellular degradation pathway mediated by highly conserved autophagy-related genes (Atgs). In our previous work, we showed that inhibiting autophagy under starvation conditions leads to significant physiological changes in the insect vector of Chagas disease Rhodnius prolixus; these…
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Scientific overview of mandibular advancement devices: a bibliometric and altmetric analysis
ABSTRACT Objective: To evaluate publications on mandibular advancement devices through bibliometric and altmetric analysis. Methods: A search was conducted in the Web of Science Core Collection (WoS-CC) initially in August 2024, with an update in December 2025, including all articles on mandibular…
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Artikel Jurnal Teks lengkap
Sports and Functional Training Improve a Subset of Obesity-Related Health Parameters in Adolescents: A Randomized Controlled Trial
To investigate the effects of two different modes of physical activity on body composition, physical fitness, cardiometabolic risk, and psychological responses in female adolescents participating in a multi-disciplinary program. The 12-week randomized intervention included 25-adolescents with…
Juga tersedia di: PubMed Central
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Artikel Jurnal Teks lengkap
Differential Responses of Liver and Hypothalamus to the Nutritional Condition During Lactation and Adult Life
It was previously reported that liver glucose metabolism in rats under caloric restriction differs from that of freely-fed rats. This study hypothesized that these changes (1) were related to the expression of hypothalamic neuropeptides involved in metabolic control, and (2) were not a residual…
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Artikel Jurnal Teks lengkap
Silencing of RpATG8 impairs the biogenesis of maternal autophagosomes in vitellogenic oocytes, but does not interrupt follicular atresia in the insect vector Rhodnius prolixus
Follicular atresia is the mechanism by which the oocyte contents are degraded during oogenesis in response to stress conditions, allowing the energetic resources stored in the developing oocytes to be reallocated to optimize female fitness. Autophagy is a conserved intracellular degradation pathway…
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Artikel Jurnal
ANÁLISE DOS PARÂMETROS DA MARCHA E DO EQUILÍBRIO DOS IDOSOS APÓS EXERCÍCIOS AERÓBICOS E TERAPÊUTICOS
O processo de envelhecimento promove alterações no organismo do idoso, que levam a comprometimentos significativos no equilíbrio corporal, reflexo e capacidade de deambulação. Nesse contexto, a atividade física é uma intervenção que vem demonstrando benefícios significativos na saúde da pessoa…
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Artikel Jurnal
Correlação entre variáveis antropométricas, composição corporal e consumo máximo de oxigênio em adolescentes com sobrepeso ou obesidade
Introdução: A obesidade infantil, têm aumentado drasticamente, mostra-se assim, uma preocupação referente ao tratamento da obesidade na infância e adolescência. Objectivo: Correlacionar variáveis antropométricas, de composição corporal e de consumo máximo de oxigénio (VO2máx) em adolescentes com…