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Unveiling bast fiber production in Upper Paleolithic North China: Microfibers and usewear traces on stone tools from Shizitan
Fiber technology—including the making of cordages, mats, baskets, and textiles—holds a crucial place in human history. However, uncovering archaeological evidence of early fiber products proves challenging due to their rapid decay. To address preservation hurdles, we employ a multi-disciplinary…
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Development and validation of the sedentary behavior regulation scale in Korean Adults Population
Sedentary behavior is a well-established independent risk factor for numerous chronic diseases. However, validated tools to assess the psychological and behavioral regulation of sedentary time remain limited. This study aimed to develop and validate a self-report scale for assessing sedentary…
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Effect of different velocity loss thresholds during a resistance training program on jump and sprint performances in trained female athletes
This study aimed to explore the effects of velocity-based resistance training (VBT) using different velocity loss (VL) thresholds on jump and sprint performance in trained female athletes. Fifteen college-level female basketball players completed an 8-week VBT program (2 sessions/week), involving…
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µCT scanning effects on aDNA and a multi-step workflow for archaeological petrous portions
The petrous portion of the temporal bone (often informally referred to as the “petrous bone”) is a key element in human evolutionary studies due to its exceptional preservation of biomolecules and morphological information. Intensive and often redundant sampling raises concerns about sustainability…
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Effective Coverage of Maternal and Newborn Health Services in Sub-Saharan Africa: What distinguishes high from medium and low performers?
Background: Effective coverage (EC) has emerged as a better measure of service coverage, in the past decades, compared to the simple crude coverage measures. It represents the proportion of a population in need of a service that successfully receives it with sufficient quality to achieve the…
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Understanding landowner preferences for traditional and nature-based solutions incentive programs in North Carolina, USA
Financial incentive programs, commonly administered by public institutions, have long supported sustainable land management practices in the United States, including soil conservation, water quality improvement, and biodiversity preservation. Recently, these initiatives have expanded under the…
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Consistent MRI pattern in ADSS1 myopathy with variable clinical presentations: A Korean cohort study
ADSS1 myopathy (previously referred to as ADSSL1 myopathy) is a rare autosomal recessive muscle disease caused by mutations in the ADSS1 gene, which encodes an enzyme critical for purine nucleotide synthesis. First characterized in Korean patients in 2016, the disease exhibits phenotypic…
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“It Feels Like My Spine is About to Break”: Experience and support needs of family caregivers of children with cerebral palsy in Ethiopia
Background: Due to the complex and long-term care needs of children with Cerebral Palsy (CP), caregivers often face an overwhelming caregiving burden, and they experience physical and psychological strain. Few studies in Sub-Saharan Africa have indicated that caregivers face financial difficulties…
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Trend-based quality assurance of binary urinary antigen tests
Objective: Binary diagnostic assays, such as urinary antigen (uAg) tests, provide rapid results but lack quantitative output for conventional quality control. This study evaluated whether long-term monitoring of test positivity patterns can serve as a practical tool for quality assurance (QA) of…
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Use of administrative data for evaluating trends in medically-attended Lyme disease, Manitoba, Canada, 2010–2021
While Lyme disease (LD) is the most common tick-borne disease reported to public health surveillance in North America and is increasingly recognized as a public health threat in Canada, it’s incidence may be underreported. Our study aims to estimate medically-attended LD incidence in Manitoba…
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Research on instrument mix and regional suitability of digital publishing industrial policies: An empirical exploration based on qualitative comparative analysis of fuzzy set
Taking the digital publishing industry as its research object and employs the fuzzy-set qualitative comparative analysis (fsQCA) method to systematically examine the causal relationships among the Instrument Mix, regional conditions, and industrial performance, drawing on policy texts and…
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Genetic, clinical, and biochemical profiling of Gilbert syndrome in a Nepali cohort: High prevalence of the UGT1A1 c.-3279T>G polymorphism and correlation with hematological parameters
Introduction: Gilbert Syndrome (GS) is a common hereditary disorder characterized by intermittent jaundice. The pathogenesis is unconjugated hyperbilirubinemia due to reduced hepatic UDP-glucuronosyltransferase 1A1 (UGT1A1) activity. Its genetic basis relies on c.-3279T > G polymorphism…
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Quality of first antenatal care visits and perinatal outcomes: Evidence from a cohort study in Ethiopia, Kenya, South Africa, and India
Antenatal care (ANC) is crucial for maternal and newborn health. Although ANC coverage has improved globally, ANC quality remains suboptimal. This study assessed the quality of first ANC visits and their association with perinatal outcomes. We used data from the eCohort study that collected…
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Ten simple rules for organising an effective student-led writing retreat
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Modelling associated factors of maternal age at first birth in Ethiopia: Gamma regression approach
Background: Maternal age at first birth (AFB) is a key indicator of reproductive health, influencing maternal and child outcomes, population dynamics, and socio-economic well-being. Early childbearing increases risks of maternal morbidity, poor neonatal outcomes, and intergenerational poverty…
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Impact of SETD8/KMT5A overexpression on hepatocellular carcinoma progression and prognosis
Background: Hepatocellular carcinoma has poor prognosis due to its high recurrence rate, even after curative surgery. Epigenetic regulators are known to play a critical role in cancer progression, and the histone methyltransferase SETD8/KMT5A has been reported to be overexpressed in various…
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Aerobactin is a key driver of hypervirulent Klebsiella pneumoniae translocation and virulence
Hypervirulent Klebsiella pneumoniae (hvKP) is an emerging pathotype capable of causing severe systemic infections. Gastrointestinal (GI) colonization often precedes invasive disease, but the mechanisms driving translocation to extra-intestinal sites are not known. A hallmark of hvKP is a large…
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Altered salience network structure–function integration underlies the decline in cognitive flexibility during aging
Cognitive flexibility supports efficient switching between mental sets and contributes to the preservation of general cognition in aging. It relies on the integration between brain functional dynamics and structural architecture. However, how this structure–function integration changes with age and…
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Action information is integrated into entorhinal representations of conceptual space and is reflected in eye movements
The hippocampal-entorhinal system represents relations between states in spatial and nonspatial cognitive maps. Critical to understanding how these memory representations are used for cognition is to determine whether the actions underlying state transitions are incorporated in entorhinal cognitive…
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One-pot nanoflower-based sensitive colorimetric biosensor for multihost detection of zoonotic clonorchiasis
Clonorchis sinensis, a significant but frequently overlooked foodborne zoonotic helminth, is responsible for infecting approximately 15 million individuals globally, poses an infection risk to nearly 200 million people, and represents a threat to public health while imposing considerable economic…
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